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產前診斷誤診帶來5000萬美金的罰款,震撼業界!
2000年,Rhea和Brock結爲夫婦,並在2002年生育了一個可愛的兒子。Brock的表妹在接受基因檢測後被診斷出患有2號和9號染色體非平衡易位,這位表妹患有嚴重的癲癇病,具有反社會傾向,身材肥胖並且只能坐在輪椅上。得知表妹的情...
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科學家研製“愛情香水”可通過體味吸引異性
...侶的。劍橋大學的動物學家蒂姆?克拉頓?布羅克(TimClutton-Brock)和哈佛大學的研究者凱瑟琳?麥考利夫(KatherineMcAuliffe)發現,嗅覺線索在雌性尋找配偶的過程中十分關鍵。 雖然和鳥類一樣,人類也會精心打扮、高視闊步,有時也...
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AssessingtheSerodiagnosticPotentialof35MycobacteriumtuberculosisProteinsandIdentificationofFourNovelSerologicalAntigens
...ecimenbankforprovidingtheserumsamplescollectedinUganda.AxelKok-Jensen,IngerBrock,andPernilleRavnarethankedfortheireffortswiththecollectionofserumsamplesinDenmark,andPatriciaGrenesandJetteFljborgarethankedfortheirvaluabletechnicalassistance.M.Singhisthankedforprovidingthe38-kDaantigenforthisstudy.Kar...
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MultiplexPCR-IdentifiedCutaneousTuberculosisEvokedbyMycobacteriumbovisBCGVaccinationinaHealthyBaby
...berculosiscomplex.J.Clin.Microbiol.36:2471-2476.Murphy,P.D.,D.L.Mayers,N.F.Brock,andK.F.Wagner.1989CureofbacilleCalmette-Guerinvaccinationabscesswitherythromycin.Rev.Infect.Dis.11:335-337.Singh,G.,andM.Singh.1984.ErythromycinforBCGcoldabscess.Lancetii:979.Talbot,E.A.,M.D.Perkins,S.F.Silva,andR.Froth...
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主動脈瓣膜部狹窄
...病變瓣膜,作人工主動脈瓣膜替換術。1952年Bailey和1954年Brock經左心室心尖部小切口,放入特製的主動脈瓣膜擴張器擴張分離融合的主動脈瓣葉交界。但因瓣膜擴張不徹底,又易引致關閉不全,療效欠滿意,乃逐漸被直視手術所...
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PeritonitisDuetoCurvulariainaequalisinanElderlyPatientUndergoingPeritonealDialysisandaReviewofSixCasesofPeritonitisAssociatedwithOtherC
...s.Clin.Infect.Dis.36:927-931.Brackett,R.W.,A.N.Shenouda,S.S.Hawkins,andW.B.Brock.1988.Curvulariainfectioncomplicatingperitonealdialysis.South.Med.J.81:943-944.Canon,H.L.,S.C.Buckingham,R.J.Wyatt,andD.P.Jones.2001.FungalperitonitiscausedbyCurvulariaspeciesinachildundergoingperitonealdialysis.Pediatr....
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顱腦外傷致精神障礙機制研究
...所致,其機制較爲複雜,特別是腦外傷後併發的許多延遲的綜合徵(post-traumaticbrainsyndrome)。隨着影像學技術的不斷髮展以及對於計算機體層攝影(CT)和磁共振成像(MRI)檢查有關內容的解釋,極大地提高了我們處理頭外傷及其併發...
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UtilityoftheAustralianNationalSubacuteandNonacutePatientCasemixClassification
...showedthegreatestimprovementbecausetheyhavethegreatestpotentialtorecover.12Brock13arguesthatpatientswithhigherinitialfunctionmightactuallyshowmoreimprovementonatoolliketheFIMbecausetheimprovementismoredifficulttoachieveandtheFIMscorelevelsarenotinterval.However,whenconsideredintermsofburdenofcare,th...
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GenomicApproachtoIdentificationofMycobacteriumbovisDiagnosticAntigensinCattle
...icrobialpathogens.Mol.Microbiol.33:1103-1117.Krebs,J.,R.Anderson,T.Clutton-Brock,I.Morrison,D.Young,andC.Donnely.1997.Bovinetuberculosisincattleandbadgers:reporttotheRt.Hon.Dr.JackCunninghamMP.MAFFPublications,London,UK.Lewin,H.A.,G.C.Russell,andE.J.Glass.1999.Comparativeorganizationandfunctionofthe...
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ReproducibilityofLowGalactomannanEnzymeImmunoassayIndexValuesTestedinMultipleLaboratories
...trecipients.Br.J.Haematol.126:852-860.Maertens,J.,J.Verhaegen,H.Demuynck,P.Brock,G.Verhoff,P.Vandenberghe,J.V.Eldere,L.Verbist,andM.Boogaerts.1999.Autopsy-controlledprospectiveevaluationofserialscreeningforcirculatinggalactomannanbyasandwichenzyme-linkedimmunosorbentassayforhematologicalpatientsatri...
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轉化生長因子-α、血管內皮生長因子與皮膚腫瘤
...血管內皮細胞膜上的兩種亞型酪氨酸激酶受體Flt-1和KDR。Brock等研究發現[11],VEGF與受體結合後細胞內短暫Ca2+濃度升高,微摩爾濃度的VEGF在幾秒內就可使Ca2+升高數倍。VEGF對內皮細胞的作用類似內皮細胞激動劑如凝血酶和組織...
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UseofReal-TimePCRToProcesstheFirstGalactomannan-PositiveSerumSampleinDiagnosingInvasiveAspergillosis
...recipients.J.Infect.Dis.186:1297-1306.Maertens,J.,J.Verhaegen,H.Demuynck,P.Brock,G.Verhoef,P.Vandenberghe,J.VanEldere,L.Verbist,andM.Boogaerts.1999.Autopsy-controlledprospectiveevaluationofserialscreeningforcirculatinggalactomannanbyasandwichenzyme-linkedimmunosorbentassayforhematologicalpatientsatr...
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Adoptivetransferofcytomegalovirus-specificCTLtostemcelltransplantpatientsafterselectionbyHLA–peptidetetramers
...allogeneicstemcelltransplantation.Blood.97:1232–1240.Kern,F.,I.P.Surel,C.Brock,B.Freistedt,H.Radtke,A.Scheffold,R.Blasczyk,P.Reinke,J.Schneider-Mergener,A.Radbruch,P.WaldenandH.D.Volk.1998.T-cellepitopemappingbyflowcytometry.Nat.Med.4:975–978.Szmania,S.,A.Galloway,M.Bruorton,P.Musk,G.Aubert,A.Ar...
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第四節 影響PCR的主要因素
...溫菌(Thermusaquatics)YT1蓖株中分離而得。此菌於1969年由Brock分離自美國黃石公園溫泉,作爲棲熱桿菌的標準菌株,其生長溫度爲70~75℃。最初從中分離到分子量60~68KDa,比活性爲2000~8000U/mg的DNA聚合酶。後來Cetus公司的KaryMullis...
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SystemToAssessGenomeSequencingNeedsforViralProteinDiagnosticsandTherapeutics
...evelopmentofaHIV-1gp41-directedvaccine.Curr.HIVRes.2:193-204.Okkels,L.M.,I.Brock,F.Follmann,E.M.Agger,S.M.Arend,T.H.Ottenhoff,F.Oftung,I.Rosenkrands,andP.Andersen.2003.PPEprotein(Rv3873)fromDNAsegmentRD1ofMycobacteriumtuberculosis:strongrecognitionofbothspecificT-cellepitopesandepitopesconservedwith...
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Disruptionofrenalperitubularbloodflowinlipopolysaccharide-inducedrenalfailure:roleofnitricoxideandcaspases
...nthepathogenesisofacuterenalfailure.CurrOpinNephrolHypertens11:301308,2002.BrockRW,CarsonMW,HarrisKA,andPotterRF.Microcirculatoryperfusiondeficitsarenotessentialforremoteparenchymalinjurywithintheliver.AmJPhysiolGastrointestLiverPhysiol277:G55G60,1999.BrownGCandBorutaiteV.Nitricoxideinhibitionofmito...
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UseofanElectronicNoseToDiagnoseMycobacteriumbovisInfectioninBadgersandCattle
...softuberculosisinbadgers.Vet.Rec.153:403-404.Krebs,J.,R.Anderson,T.Clutton-Brock,I.Morrison,D.Young,andC.Donnelly.1997.Bovinetuberculosisincattleandbadgers—reportbytheIndependentScientificReviewGroup.MinistryofAgriculture,FisheriesandFood,London,UnitedKingdom.Lai,S.Y.,O.F.Deffenderfer,W.Hanson,M.P...
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低溫停循環與神經元凋亡
...循環會帶來不可避免的腦損傷,NO在其中有重要的作用。Brock等使用L-[14C]-精氨酸作爲NO生成的指標對狗進行實驗,證明低溫停循環導致nNOS早期、明顯的表達,使腦內NO廣泛增多;用細胞免疫化學方法標記NOS特異的單克隆抗...
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Contributionof(13)--D-GlucanChromogenicAssaytoDiagnosisandTherapeuticMonitoringofInvasiveAspergillosisinNeutropenicAdultPatients:aComparison
...recipients.J.Infect.Dis.186:1297-1306.Maertens,J.,J.Verhaegen,H.Demuynck,P.Brock,G.Verhoef,P.Vandenberghe,J.VanEldere,L.Verbist,andM.Boogaerts.1999.Autopsy-controlledprospectiveevaluationofserialscreeningforcirculatinggalactomannanbyasandwichenzyme-linkedimmunosorbentassayforhematologicalpatientsatr...
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DetectionofAspergillusGalactomannanAntigenemiaToDetermineBiologicalandClinicalImplicationsofBeta-LactamTreatments
...pectivevalidation.Blood97:1604-1610.Maertens,J.J.,J.Verhaegan,H.Demuynck,P.Brock,G.Verhoef,P.Vandenberghe,J.VanEldere,L.Verbist,andM.Boogaerts.1999.Autopsy-controlledprospectiveevaluationofserialscreeningforcirculatinggalactomannanbyasandwichenzyme-linkedimmunosorbentassayforhematologicalpatientsatr...
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RecurrentColonizationofSuccessivelyImplantedTracheoesophagealVocalProsthesesbyaMemberoftheFusariumsolaniSpeciesComplex
...therDNA-ITSregion.Mycol.Res.104:1175-1183.Sugiura,Y.,J.R.Barr,D.B.Barr,J.W.Brock,C.M.Elie,Y.Ueno,D.G.Patterson,M.E.Potter,andE.Reiss.1999.PhysiologicalcharacteristicsandmycotoxinsofhumanclinicalisolatesofFusariumspecies.Mycol.Res.103:1462-1468.Summerbell,R.C.2003.Aspergillus,Fusarium,Sporothrix,Pied...
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法樂四聯症
...早期可能發生的併發症有出血、房室傳導阻滯、低心排血綜合徵、心力衰竭、肺間質及肺泡水腫引致呼吸衰竭等。【病因學】1970年VanPraagh等認爲四聯症的胚胎髮育障礙是由於肺動脈圓錐遠段或右心室漏斗部發育不全,未發生反...
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風溼性二尖瓣狹窄
...徑用手指分離擴大二尖瓣瓣口。1947~1948年Harken,Bailey,BroCk等先後經左心耳行閉式二尖瓣交界擴張分離術,療效良好。1954年Neptune和Bailey又報道經右胸房間溝切口施行二尖瓣交界分離術。這個手術途徑可避免術中手指觸動左心耳...
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IdentificationofDifferentialProteinExpressionAssociatedwithDevelopmentofUnstableHumanCarotidPlaques
...riosclerThrombVascBiol2003,23:2165-2171DelMaschioA,DeLuigiA,Martin-PaduraI,Brock-hausM,BartfaiT,FruscellaP,AdoriniL,MartinoG,FurlanR,DeSimoniMG,DejanaE:Leukocyterecruitmentinthecerebrospinalfluidofmicewithexperimentalmeningitisisinhibitedbyanantibodytojunctionaladhesionmolecule(JAM).JExpMed1999,190:...
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UseofrMPB70ProteinandESAT-6PeptideasAntigensforComparisonoftheEnzyme-LinkedImmunosorbent,Immunochromatographic,andLatexBeadAgglutinationAs
...J.Vet.Microbiol.78:111-117.Skjot,R.L.V.,T.Oettinger,I.Rosenkrands,P.Ravn,I.Brock,S.Jacobsen,andP.Andersen.2000.Comparativeevaluationoflow-molecular-massproteinsfromMycobacteriumtuberculosisidentifiesmembersoftheESAT-6familyasimmunodominantT-cellantigens.Infect.Immun.68:214-220.Sorensen,A.L.,S.Nagai,...
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常見綜合徵外治獨特新療法——內病外治·外病外治獨特新療法叢書
...外治·外病外治獨特新療法叢書》之分冊。主要闡述常見綜合徵外治獨特新療法。共分上、中、下篇。上篇爲總論;中篇爲各論;下篇爲常見綜合徵外治藥物高效驗方選萃。本書有較強地實用性,可供中醫、中西醫結合臨牀醫生...
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顱腦綜合徵的CT、MRI診斷
...0版次:1a內容提要:本書收集臨牀罕見的涉及顱腦的167個綜合徵,分別介紹其病因、病理、臨牀表現、CT和MRI診斷,旨在使放射科醫師熟悉掌握各綜合徵的臨牀特徵、CT和MRI表現及其病理基礎,拓寬診斷思路,提高影像診斷水平...
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南方沿海地區圍產兒胎兒水腫綜合徵篩查分析
【摘要】的瞭解欽州市48738例圍產兒胎兒水腫綜合徵相關因素。方法對欽州市12家出生缺陷監測醫院48738例住院分娩的孕滿28周至產後7d內的圍產兒進行監測。結果胎兒水腫綜合徵359例,胎兒水腫綜合徵發生率73.66/萬;每年的胎兒...
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HELLP綜合徵13例臨牀分析
【摘要】目的分析13例HELLP綜合徵臨牀特點,探討該病的診斷和治療方法。方法對雲南省昆明市及雲南省宣威市部分醫院2007年1月-2009年1月發生的13例HELLP綜合徵患者的臨牀資料進行回顧性分析。結果13例HELLP綜合徵發病孕周爲28~39...
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Brugada綜合徵及其相關疾病研究進展
...圖特點。基於此,他們概括了一種新的、後被稱爲Brugada綜合徵的“獨特的臨牀和心電圖綜合徵”。 據估計,在一些國家的所有特發性心室顫動(VF)病例中,與這種心電圖特徵相聯繫的VF高達40%~60%。現已明確,“心臟組織...