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RecurrenceofThiel-Behnkecornealdystrophy:anelectronmicroscopicstudy
...-Behnkecornealdystrophy,firstdescribedin1967,1isfrequentlyconfusedwithReis-Bucklersdystrophy.BothconditionsaffectBowman’slayerandcanbedifficulttodifferentiatebothclinicallyandhistopathologically.Previously,electronmicroscopicstudiesofcornealdystrophiesaffectingBowman’slayeridentifiedcharacterist...
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基底細胞樣乳癌臨牀病理分析
...細胞化生。提示BLBC部分具有髓樣癌和化生性癌的特點。REIS-FILHO等[8]的研究顯示,化生性癌常常具有肌上皮表型,並推測BLBC可能是各種帶有肌上皮表型腫瘤的最終進展結果。該觀點值得商榷,因爲梭形細胞或鱗狀細胞化生是化生...
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ReliabilityoftheE-TestMethodforDetectionofColistinResistanceinClinicalIsolatesofAcinetobacterbaumannii
...lsurveillanceprogram,1997and1998.Clin.Infect.Dis.30:454-460.Gales,A.C.,A.O.Reis,andR.N.Jones.2001.ContemporaryassessmentofantimicrobialsusceptibilitytestingmethodsforpolymyxinBandcolistin:reviewofavailableinterpretativecriteriaandqualitycontrolguidelines.J.Clin.Microbiol.39:183-190.Garnacho-Montero,...
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腸梗阻患者圍手術期的處理
...而減少細菌移位率。這一結論尚待臨牀實踐證實。 4營養支持治療 圍手術期營養支持,一般來說是指腸梗阻特別是慢性腸梗阻術前有中度以上營養不良,或術後較長時期(約10天以上)不能正常進食的患者,給予適當營養補...
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原發性高血壓患者生活質量及其影響因素的研究現狀
...明顯,性活動減少,睡眠障礙,娛樂活動減少,自我感覺不良方面均顯著高於非神經質個體。Eysenck[13]認爲神經質可能與交感神經和副交感神經的功能以及邊緣系統對情緒和控制能力有關,神經質個體容易產生焦慮、抑鬱以及...
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成人股骨頭缺血性壞死的治療進展
...死。股骨頭壞死也是由於多種原因導致的股骨頭局部血運不良,從而進一步缺血、壞死、骨小梁斷裂、股骨頭塌陷的一種病變。這種疾病可發生於任何年齡,但以31~60歲最多,無性別差異。開始多表現爲髖關節或其關節周圍的...
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QualityControlGuidelinesforTestingGram-NegativeControlStrainswithPolymyxinBandColistin(PolymyxinE)byStandardizedMethods
...iresistantgram-negativebacteria.Ann.Pharmacother.33:960-967.Gales,A.C.,A.O.Reis,andR.N.Jones.2001.ContemporaryassessmentofantimicrobialsusceptibilitytestingmethodsforpolymyxinBandcolistin:reviewofavailableinterpretativecriteriaandqualitycontrolguidelines.J.Clin.Microbiol.39:183-190.Levin,A.S.,A.A.Ba...
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125I粒子組織間植入對小鼠Lewis肺癌細胞VEGFC和COX2表達影響
...在淋巴結轉移的發生中起着重要的作用,是一獨立的預後不良因素,其表達強度與淋巴結轉移和預後有密切的關係。這在頭頸部腫瘤、乳癌、胃癌、結直腸癌、前列腺癌、宮頸癌等惡性腫瘤的淋巴道轉移中有相關報道,但是目前...
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輕中度高血壓患者早期腎損害與脈壓的關係
...2-MG)andtheurineβ2-microglobulin、albumininpatientswithwhosepulsepressureis60mmHgarehigherthanwhosepulsepressureis60mmHg.ConclusionTherenalinjuryismoresevereinhyper-tensionpatientswithwhosepulsepressureishigher. 【Keywords】pulsepressure;renalinjury;hypertension 高血壓是最常見...
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胃癌癌前病變多基因改變研究進展
...弱表達,而在腸化生粘膜的過增生區域及胃小凹表面分化不良的細胞中均可檢測到bcl-2,這些分化不良的細胞正是胃癌癌前病變的一個重要特徵。因此推測,胃粘膜受損傷後增生加快,導致一些分化不良的細胞出現,這些分不良...
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DirectDetectionofNocardiaspp.inClinicalSamplesbyaRapidMolecularMethod
...luidindicatepneumococcaletiologyinacuteotitismediaJ.Infect.Dis.189:775-784.Reis,M.A.,R.S.Costa,andA.S.Ferraz.1995.Causesofdeathinrenaltransplantrecipients:astudyof102autopsiesfrom1968to1991.J.R.Soc.Med.88:24-27.Scarparo,C.,P.Piccoli,A.Rigon,G.Ruggiero,M.Scagnelli,andC.Piersimoni.2000.Comparisonofenh...
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PenicillinSusceptibilityandEpidemiologicalTypingofInvasivePneumococcalIsolatesintheRepublicofIreland
...types(Fig.2).Amongthe144isolatesstudied,24PFGEtypes,eachrepresentingtwoormoreisolateswereobserved(Table2).Afurther10PFGEtypesdifferingbyatleast23%fromotherswerealsoobserved,eachofwhichwererepresentedbyasingleisolateonly.fig.ommittedFIG.2.Geneticrelatednessof144isolatesofS.pneumoniaeandtheATCC49619st...
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FirstIsolationofMetallo--Lactamase-ProducingMultiresistantKlebsiellapneumoniaefromaPatientinBrazil
...o--lactamase.J.Antimicrob.Chemother.52:699-702.Gales,A.C.,M.C.B.Tognim,A.O.Reis,R.N.Jones,andH.S.Sader.2003.EmergenceofanIMP-likemetallo-enzymeinanAcinetobacterbaumanniiclinicalstrainfromaBrazilianteachinghospital.Diagn.Microbiol.Infect.Dis.45:77-79.Giakkoupi,P.,A.Xanthaki,M.Kanelopoulou,A.Vlahaki,V...
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EpidemiologyofHumanSporotrichosisInvestigatedbyAmplifiedFragmentLengthPolymorphism
...nofmedicalfungi(http://www.belspo.be/bccm/ihem.htm).AllthePeruvianstrainswereisolatedandidentifiedintheMycologyLaboratoryoftheInstitutodeMedicinaTropical“AlexandervonHumboldt,“UniversidadPeruanaCayetanoHeredia,inLima,Peru.AllMexicanstrainswerekindlyprovidedbyH.Torres-Guerrero(UniversidadNacional...
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經尿道前列腺汽化電切術後併發症的防治體會
...pectsofthedominantoperationI,AmericanUrologyJUrol.1989,141:248. 2TeAE,Reis,R,KaplanSA.TVP:anewmodificationofTURP.ContempUrol,1995,7:74-79. 3TeAK,KaplanSA.Transurethralelectrovaporizationoftheprostate,theyearinreview.CurrentopinioninUrology,1997,7:25-31. 4秦曉濤,盧一平.尿道...
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Ironneedsduringpregnancy:doweneedtorethinkourtargets?
...directironsupplementationduringpregnancyisneededunlessthepreexistingironstoreis500mg,indicatesclearlythatthe1988FAO/WHOcommittee(3)wasresignedtotheapparentneedforroutineironsupplementationinpregnancy.AlthoughIchairedbothoftheabovecommittees,Iadmittobeingveryconcernedthatepidemiologicevidence,evenjus...
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地震災害傷員的擠壓傷早期處理
...壓力升高,壓迫血管、神經和肌肉細胞,由於缺氧和沒有營養,神經和肌細胞在數小時後死亡。2.2筋膜間室綜合徵的原因筋膜間室綜合徵的原因有創傷(血腫、咬傷、擠壓傷),導致腫脹的疾病(凍傷、燒傷、過勞),凝血障礙(遺傳...
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BreakpointsforPredictingPseudomonasaeruginosaSusceptibilitytoInhaledTobramycininCysticFibrosisPatients:UseofHigh-RangeEtestStrips
...incysticfibrosis:aEuropeanconsensus.J.CysticFibrosis3:67-91.Gales,A.C.,A.O.Reis,andR.N.Jones.2001.ContemporaryassessmentofantimicrobialsusceptibilitytestingmethodsforpolymyxinBandcolistin:reviewofavailableinterpretativecriteriaandqualitycontrolguidelines.J.Clin.Microbiol.39:183-190.Geller,D.E.,W.H.P...
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IdentificationofVariable-NumberTandem-RepeatLociinLeptospirainterrogansSensuStricto
...ae,E.G.Lemos,M.V.Lemos,C.L.Marino,L.R.Nunes,R.C.deOliveira,G.G.Pereira,M.S.Reis,A.Schriefer,W.J.Siqueira,P.Sommer,S.M.Tsai,A.J.Simpson,J.A.Ferro,L.E.Camargo,J.P.Kitajima,J.C.Setubal,andM.A.VanSluys.2004.ComparativegenomicsoftwoLeptospirainterrogansserovarsrevealsnovelinsightsintophysiologyandpathoge...
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CharacterizationofBorrelialusitaniaeIsolatesCollectedinTunisiaandMorocco
...icrobiol.42:1316-1318.DeMichelis,S.,H.S.Sewell,M.Collares-Pereira,M.Santos-Reis,L.M.Schouls,V.Benes,E.C.Holmes,andK.Kurtenbach.2000.GeneticdiversityofBorreliaburgdorferisensulatointicksfrommainlandPortugal.J.Clin.Microbiol.38:2128-2133.Dykhuizen,D.E.,andG.Baranton.2001.Borreliaburgdorferi,a(somewhat...
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IsolationofCandidafamatafromaPatientwithAcuteZonalOccultOuterRetinopathy
...itissimulatingPropionibacteriumacnessyndrome.Arch.Ophthalmol.109:1718-1721.Reis,A.,R.Sundmacher,K.Tintelnot,H.Agostini,H.E.Jensen,andC.Althaus.2000.Successfultreatmentofocularinvasivemouldinfection(fusariosis)withthenewantifungalagentvoriconazole.Br.J.Ophthalmol.84:932-933.RubioCalvo,M.C.,J.Gil,I.Ra...
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InvivoanalysisoftheroleofaberranthistonedeacetylaserecruitmentandRARblockadeinthepathogenesisofacutepromyelocyticleukemia
....Proc.Natl.Acad.Sci.USA.96:6318–6323.Sukhai,M.A.,X.Wu,Y.Xuan,T.Zhang,P.P.Reis,K.Dube,E.M.Rego,M.Bhaumik,D.J.Bailey,R.A.Wells,etal.2004.MyeloidleukemiawithpromyelocyticfeaturesintransgenicmiceexpressinghCG-NuMA-RAR.Oncogene.23:665–678.Rountree,M.R.,K.E.Bachman,J.G.Herman,andS.B.Baylin.2001.DNAmet...
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RNA-associatedautoantigensactivateBcellsbycombinedBcellantigenreceptor/Toll-likereceptor7engagement
...matosus.J.Clin.Invest.94:184–192.Diebold,S.S.,T.Kaisho,H.Hemmi,S.Akira,C.Reis,andE.Sousa.2004.InnateantiviralresponsesbymeansofTLR7-mediatedrecognitionofsingle-strandedRNA.Science.303:1529–1531.Heil,F.,H.Hemmi,H.Hochrein,F.Ampenberger,C.Kirschning,S.Akira,G.Lipford,H.Wagner,andS.Bauer.2004.Speci...
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Thermolabilemethylenetetrahydrofolatereductase,homocysteine,andcardiovasculardiseaserisk:theEuropeanConcertedActionProject
...Vitamins,ArmauerHansensHus,UniversityofBergen,Bergen,Norway),RobertoJPalma-Reis(ServicodeMedicina,HospitaldeSFranciscoXavier,Lisbon),GodfriedHJBoers(DepartmentofMedicine,UniversityHospital,Nijmegen,Netherlands),RichardGSheahan(DivisionofCardiology,UniversityofNorthCarolinaSchoolofMedicine),BoIsraels...
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RapidDevelopmentofSalivaryGlandCarcinomasuponConditionalExpressionofK-rasDrivenbytheCytokeratinPromoter
...roundingglandularstructures.InE,thecarcinomatousareaontheleftsideofthepictureisnegative(arrows),whereasthehyperplasticglandsontherightsideshowpositiveperiglandularmyoepithelialcells.FandG:Scatteredimmunoreactivityforp63innormalsubmaxillaryandsublingualglandsrespectively(emptyarrows:ductalcells;arrow...
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ComparisonofBorreliaburgdorferiSensuLatoStrainsIsolatedfromSpecimensObtainedSimultaneouslyfromTwoDifferentSitesofInfectioninIndividualPati
...heassessmentofthepresenceandmolecularmassesofseparatedproteins.Thestrainswereisolatedfromtwodistinctskinlesions(12patients),skinandblood(28patients),skinandcerebrospinalfluid(8patients),andbloodandcerebrospinalfluid(2patients).Outof100isolates,63weretypedasB.afzeliiand37asB.garinii.Fromeachindividua...
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PreclinicalandClinicalPerformanceoftheEfooraTest,aRapidTestforDetectionofHumanImmunodeficiencyVirus-SpecificAntibodies
...apidtestisaunidirectional,lateral-flowimmunochromatographicdevicetowhichthereisbindingandconcentrationofanti-HIVantibodiestoHIVantigenslocatedatthetestlineonthedevice,followedbydetectionofboundantibodieswithcolloidalgold-labeledconjugate(Fig.1).Theplastichousingholdsareagentpadcontaininganantibody-b...
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AlterationsofGeneExpressionintheDevelopmentofEarlyHyperplasticPrecursorsofBreastCancer
...hyperplasticprecursorsMaterialsandMethodsTissueSamples95%)epithelialcellswereisolatedfromtheTDLUsandHELUsineachbiopsy(25,000cellspersample)bylasercapturemicrodissection(Veritas;Arcturus,MountainView,CA)(Figure1).TenadditionalpairedsamplesofTDLUsandHELUsfromindependentFFPETbiopsieswerepreparedinasimi...
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DetectionofPseudomonasaeruginosaProducingMetallo--LactamasesinaLargeCentralizedLaboratory
...albacterialstrains.Ofthe241IPM-nonsusceptibleP.aeruginosastrains,103(43%)wereisolatedfromurine,17(7%)fromblood,50(21%)fromwounds(purulent),48(20%)fromrespiratorytractspecimens,andtheremaining23(9%)fromvariousotherspecimens.TheisolatesproducingMBLsweremoreprevalentinbloodcultures(13%versus3%)andlessp...
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Plasmacytoidpredendriticcellsinitiatepsoriasisthroughinterferon-production
...Nat.Rev.Immunol.4:211–222.Diebold,S.S.,T.Kaisho,H.Hemmi,S.Akira,andE.S.C.Reis.2004.InnateantiviralresponsesbymeansofTLR7-mediatedrecognitionofsingle-strandedRNA.Science.303:1529–1531.Lang,K.S.,M.Recher,T.Junt,A.A.Navarini,N.L.Harris,S.Freigang,B.Odermatt,C.Conrad,L.M.Ittner,S.Bauer,etal.2005.Tol...