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IntragenicSuppressionofTrafficking-DefectiveKCNH2ChannelsAssociatedwithLongQTSyndrome
...genicsuppressionoftheclass2LQT2V612LandF640VphenotypesbutnottheLQT2N470DorF805Cphenotypes.ThesearethefirstfindingstodemonstratethatasingleaminoacidsubstitutionintheputativeKCNH2drugbindingdomaincancauseintragenicsuppressionofseveralLQT2mutations.TheKCNH2orthehumanether-a-go-gorelatedgene(hERG)encode...
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Applicationoffemtosecondultrashortpulselasertophotodynamictherapymediatedbyindocyaninegreen
...eforuseasaphotosensitiserwithminimaladverseeffects.ICGhasanabsorptionpeakat805nm,whichissimilartothewavelengthofthetitaniumsapphirelaseratthenearinfraredlevel.Wecombinedhighpeakpowerpulseenergy,whichcauseslesscollateraldamagebythetitaniumsapphirelaser,withPDTmediatedbyICG.Toevaluatethiscombination,c...
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他唑巴坦及其製劑注射用哌拉西林鈉/他唑巴坦鈉的HPLC含量測定方法的建立
...5mol.L-1的磷酸二氫鉀水溶液-2.5mmol.L-1四丁基氫氧化銨(180∶805∶15),檢測波長爲230nm,流速:1mL.min-1;注射用哌拉西林鈉/他唑巴坦鈉的HPLC含量測定色譜條件:C18柱,流動相爲pH3.5的甲醇-水-2.5mmol.L-1四丁基氫氧化銨(450∶535∶15),檢...
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尿液標本805份細菌培養結果與病原菌的耐藥性檢測
【摘要】對我院2001年1月~2003年11月805份臨牀診斷爲泌尿系感染病人的尿液標本進行了細菌培養及藥敏試驗,其中陽性標本(細胞計數高於104~5CFU/ml)289份,陽性率分別爲2001年的28%、2002年的34.9%、2003年的43.6%,呈逐年上升趨勢...
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RepetitiveTranscranialMagneticStimulationofContralesionalPrimaryMotorCortexImprovesHandFunctionAfterStroke
...yrepetitivetranscranialmagneticstimulation.ClinNeurophysiol.2000;111:800–805.KapurN.Paradoxicalfunctionalfacilitationinbrain-behaviourresearch.Acriticalreview.Brain.1996;119:1775–1790.KobayashiM,HutchinsonS,TheoretH,SchlaugG,Pascual-LeoneA.RepetitiveTMSofthemotorcorteximprovesipsilateralsequenti...
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第三節 單向免疫擴散法
... 劑抗 血 清 RID 法效 價20253040608024.0g/L瓊脂(ml)5.805.805.805.805.805.80硫柳汞鹽水(ml)5.225.345.415.515.615.65抗血清(ml)0.580.460.390.290.190.15 將稀釋的抗血清傾入已融化的瓊脂糖中,顛倒混勻1~2次,避免產生氣泡,迅速澆注預置水...
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武進醫院綜合性ICU細菌耐藥監測
...情況,現將ICU在2004年全年細菌耐藥情況進行分析。 表1805株細菌分佈及構成比(略) 1資料與方法 1.1菌株收集我院ICU2004年1—12月分離出的細菌805株。採用標準方法獲得標本。標本來源主要來自下呼吸道、泌尿道及靜脈...
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腎癌組織中IGFⅠ和IGFⅠR表達及其臨牀意義
...amongwomenwithclearcellrenalcellcarcinoma\[J\].HumPathol,2002,33(8):801-805. \[9\]ParkerAS,ChevilleJC,LohseC,etal.ExpressionofinsulinlikegrowthfactorⅠreceptorandsurvivalinpatientswithclearcellrenalcellcarcinoma\[J\].JUrol,2003,170(2pt1):420-424. \[10\]BurtrumD,ZhuZ,LuD,etal.Aful...
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羅格列酮對大鼠氣道黏液高分泌的影響
...白、MUCSAC表達分別呈正相關(r分別爲0.827,0.795,0.924,0.805,0.812和0.917,P<0.01或P<0.05)。給予低、中、高劑量羅格列酮治療後,D組、E組和F組BALF中TNF-α和IL-8濃度,以及氣道黏蛋白和MUC5AC表達均逐漸降低,其中E、F組與C、D組比較...
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大鼠缺血再灌流腦區半胱氨酸蛋白酶-3活化與神經元凋亡的關係
...神經元的密度(細胞數/0.1mm2)的變化彼此間均呈正相關(r=0.805~0.942,P<0.01);除6h與12h組間PARP含量的差異及6h與12h組間和12h與24h組間PARP陽性神經元密度的差異無統計學意義外,上述6種指標的其餘組間差異均有統計學意義。可見再灌...
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IschemicThresholdsforGrayandWhiteMatter
...quartilerange0.94to1.53;P0.0001),ADC(GM:918x10–6mm2/s;868to975x10–6;WM:805x10–6;747to870x10–6;P0.001),andtherewasatrendtowardashorterMTTinGM(GM4.94s,4.44to5.38;WM5.15,4.11to5.68;P=0.11).Conclusions—GMhasahigherinfarctionthresholdforCBF,CBV,andADCthanWMinpatientswithin24hoursofischemicstrok...
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ClinicalSignificanceandEpidemiologicAnalysesofMycobacteriumaviumandMycobacteriumintracellulareamongPatientswithoutAIDS
...dratewasalsosignificantlyhigherthanthatamongmenandwomenofothergroups(35of2,805versus27of4,667,2=9.54,P=0.002).Therefore,hematologictumorspredisposedtoM.aviumcolonizationorcontaminationbutnotinfection(seebelow).Moreculturesinthesepatients(mean,2.31/patient)thanthoseinothergroups(mean,1.55)werealsoaco...
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EffectofInoculumSizeonDetectionofCandidaGrowthbytheBACTEC9240AutomatedBloodCultureSystemUsingAerobicandAnaerobicMedia
...odculturesinpatientswithcandidaemia.Eur.J.Clin.Microbiol.Infect.Dis.19:803-805.Bourbeau,P.P.,andJ.K.Pohlman.2001.ThreedaysofincubationmaybesufficientforroutinebloodcultureswithBactT/AlertFANbloodculturebottles.J.Clin.Microbiol.39:2079-2082.Edmond,M.B.,S.E.Wallace,D.K.McClish,M.A.Pfaller,R.N.Jones,an...
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中國研究者探討多發性硬化患者糖皮質激素受體蛋白和mRNA表達與激素療效的相關性
...者GRαmRNA的表達水平(0.792±0.177)與健康對照組(0.805±0.158)差異無統計學意義,而SPMS患者的表達水平(0.315±0.129)明顯低於健康對照(P〈0.05)。(3)RRMS和SPMS患者PBMC中均有GRβmRNA的表達,健康對照組未檢出GRβmRNA表...
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NosocomialSpreadofaStaphylococcushominissubsp.novobiosepticusStrainCausingSepsisinaNeonatalIntensiveCareUnit
...thahighprevalenceofoxacillinandfluoroquinoloneresistance.Res.Microbiol.152:805-810.Geha,D.J.,J.R.Uhl,C.A.Gustaferro,andD.H.Persing.1994.MultiplexPCRforidentificationofmethicillin-resistantstaphylococciintheclinicallaboratory.J.Clin.Microbiol.32:1768-1772.Hall,S.L.1991.Coagulase-negativestaphylococca...
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高效液相色譜法測定葡萄糖和甘露醇
...-Ⅲ泵;851-AS型智能取樣器;PC-9801ns/T型筆記本電腦(安裝805數據站)。水:重蒸水;葡萄糖(分析純);甘露醇(分析純);D-山梨醇(分析純);輸血用紅細胞保存液(MAP液)。2.2 色譜條件 色譜柱:磺化聚苯乙烯類凝膠填...
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糖尿病患者血清超敏C反應蛋白變化的研究
...葉任高.內科學[M].第5版,北京:人民衛生出版社,2002,805~806. [2]RossR.Atherosclerosis-aninflammatorydisease[J].NEnglJ,1999,115~126. [3]TonariY,ChidaM,KoyamaT,etal.EstblishmentofareferenceintervalforhighlysensitiveCRPbyexclusinonofindividuals...
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Effectoftrabeculectomyonocularbloodflow
...aucomaandsystemicmedicationsonocularbloodflow.ProgRetinEyeRes2003;22:769–805.作者:FBerisha1,KSchmetterer2,CVass2,SDallinger1,
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近紅外脈衝光用於乳腺疾病檢測的動態特性研究
...譜區域,去氧血紅蛋白的吸收係數比含氧血紅蛋白小;在805nm左右爲等吸收點,去氧血紅蛋白與含氧血紅蛋白具有相同的吸收係數。本實驗所用的波長選擇在805這個等吸收點的左右,760nm代表着去氧血紅蛋白的吸收情況,850nm代表...
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高效液相色譜法測定百癬夏塔熱膠囊中沒食子酸的含量
...藥苦蔘鹼對照品由中國藥品生物製品檢定所提供(批號:805-200206),乙腈爲色譜純,其餘試劑均爲分析純,水爲雙蒸水,複方苦蔘洗劑樣品爲自制。2方法與結果2.1色譜條件與系統適用性色譜柱KromosilODSC18(5μm,4.6mm×200mm),乙腈...
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TheUseofEmbolicSignalDetectioninMulticenterTrialstoEvaluateAntiplateletEfficacy
...iningprocedure.Agreementbetweenpost-trialvalidatorandcentralreaderwasps+=0.805,indicatingverygoodagreement.Correlationbetweenonlineevaluationandoff-lineevaluationofDATswasverygoodoverall(cumulative=0.84;P0.001).Conclusion—MulticenterstudiesusingMESasoutcomeparameterarefeasible.However,primaryandse...
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GenomicRelatednessoftheNewMatlabVariantsofVibriocholeraeO1totheClassicalandElTorBiotypesasDeterminedbyPulsed-FieldGelElectrophoresis
...uque.1983.ClassicalVibriocholeraebiotypedisplacesElTorinBangladesh.Lanceti:805-807.Siddique,A.K.,A.H.Baqui,A.Eusof,K.Haider,M.A.Hossain,I.Bashir,andK.Zaman.1991.SurvivalofclassiccholerainBangladesh.Lancet337:1125-1127.Talukder,K.A.,Z.Islam,M.A.Islam,D.K.Dutta,A.Safa,M.Ansaruzzaman,A.S.G.Faruque,S.N....
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TowardimprovedimmunocompetenceofadoptivelytransferredCD8+Tcells
...cchia,A.2001..ExploringpathwaysformemoryTcellgeneration.J.Clin.Invest.108::805-806.doi:10.1172/JCI200114005.Kaech,S.M.,Wherry,E.J.,andAhmed,R.2002..EffectorandmemoryT-celldifferentiation:implicationsforvaccinedevelopment.Nat.Rev.Immunol.2::251-262.Masopust,D.,andLefrancois,L.2003..CD8T-cellmemory:th...
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GeneticDiversityofMultidrug-ResistantMycobacteriumtuberculosisIsolatesandIdentificationof11NovelrpoBAllelesinTaiwan
....1994.TherpoBgeneofMycobacteriumtuberculosis.Antimicrob.AgentsChemother.38:805-811.Moss,A.R.,D.Alland,E.Telzak,D.Hewlett,Jr.,V.Sharp,P.Chiliade,V.LaBombardi,D.Kabus,B.Hanna,L.Palumbo,K.Brudney,A.Weltman,K.Stoeckle,K.Chirgwin,M.Simberkoff,S.Moghazeh,W.Eisner,M.Lutfey,andB.Kreiswirth.1997.Acity-wideou...
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人臍帶血幹細胞移植可影響急性心肌梗死後心室重構
...對照組非梗死區心肌中AngⅡ含量與OPNmRNA表達呈正相關(r=0.805,P<0.05)圖6實驗組非梗死區心肌中AngⅡ含量與OPNmRNA表達呈正相關(r=0.892,P<0.05)【參考文獻】 [1]ZhangRC,DongNG,HouJF,etal.Influenceoftransplantationofallogenicbonemarrowmononuclearcellsontheleftve...
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精神病患者院內感染的預防和控制對策
...護理技術操作常規,第4版.北京:人民軍醫出版社,1998,809;805-807;831. 作者單位:618200四川綿竹,綿竹市精神病專科醫院 (編輯:鄧鋒) 【中圖分類號】R473.74 隨着社會的發展變革,社會競爭日趨激烈,精神病患者逐漸...
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手足口病與全身炎症反應綜合徵的臨牀研究
...亞美.實用兒科學,第6版.北京:人民衛生出版社,1997,805. 作者單位:066000河北秦皇島,秦皇島市第一醫院兒科 (編輯:喬曉)作者:王桂蘭
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DifferentialIntracellularSignalingthroughPAC1IsoformsasaResultofAlternativeSplicingintheFirstExtracellularDomainandtheThirdIntracellularL
...ngtheregionscodingfortheEC1domainandtheIC3loopweredetectedassinglebands.The805-,791-,767-,and753-bpamplificationproductscorrespondtotheN/HOP1,S/HOP1,N/R,andS/Risoforms,respectively.c,thelinearrangeofamplificationsofthefourPAC1isoformswereverifiedbyvaryingthenumberofPCRcycles(25,30,and35)inbrain,hear...
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薄層掃描法測定心安顆粒中苦蔘鹼的含量
...參鹼對照品(中國藥品生物製品檢定所,供含量測定用,805-200005),心安顆粒(瀘州醫學院新藥中試中心)。 2、試驗條件 2.1薄層色譜條件展開劑爲苯-丙酮-醋酸乙酯-濃氨試液(2:3:4:0.2),顯色方法:噴以碘化鉍鉀試液,...
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複方替硝唑霜
...單甘脂4g,白凡士林5.0g,液體石蠟油2.0g,甘油10g,吐溫-805g,蒸餾水加至100g。1.2製法取硬脂酸、單甘脂、白凡士林、液體石蠟油(油相),另取替硝唑、硫酸鋅、蒸餾水(水相),將兩相分別置於適當容器中加熱至熔化或溶解...