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Infantgrowthandhealthoutcomesassociatedwith3comparedwith6moofexclusivebreastfeeding
...dBiostatistics(MSK,TG,RWP,J-PC,SS,andTD),McGillUniversityFacultyofMedicine,Montreal;theCentreforResearchinWomensHealth(BC),SunnybrookWomensCollegeHealthSciencesCentre(BC),andFacultyofNursing(EH),UniversityofToronto;theDepartmentsofMaternalandChildHealth(ZS)andForeignRelations(IM),Belarus...
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DownregulationofrenalvasopressinV2receptorandaquaporin-2expressionparallelsage-associateddefectsinurineconcentration
...】Renalconcentratingabilityisknowntobeimpairedwithaging.TheantidiuretichormoneAVPplaysanimportantroleinrenalwaterexcretionbyregulatingthemembraneinsertionandabundanceofthewaterchannelaquaporin-2(AQP2);thiseffectisprimarilymediatedviatheV2subtypeoftheAVPreceptor(V2R).Thisstudyevaluatedthehypothesist...
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EarlyinfantfeedingandgrowthstatusofUS-borninfantsandchildrenaged471mo:analysesfromthethirdNationalHealthandNutritionExaminationSu
...ctiveofthisstudywastodeterminewhetherinfantswhoareexclusivelybreast-fedfor4modifferinaveragesizefrominfantswhoarefedinotherwaysandwhethersuchdifferencespersistthroughage5y.Design:DatafromthethirdNationalHealthandNutritionExaminationSurvey(NHANESIII)werelinkedtobirthcertificatesofUS-borninfantsandchi...
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LongitudinalmeasuresofcirculatingleptinandghrelinconcentrationsareassociatedwiththegrowthofyoungPeruvianchildrenbutarenotaffectedbyzinc
...tyofCalifornia,Davis,Davis,CA;InstitutodeInvestigaciónNutricional,LaMolina,Lima,Perú(DLdRandMEP);andtheUSDepartmentofAgriculture,AgriculturalResearchCenter,WesternHumanNutritionResearchCenter,Davis,CA(MDVL)2SupportedbytheBillandMelindaGatesFoundation.3Reprintsnotavailable.Addresscorres...
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Lactationalamenorrheaisassociatedwithchildageatthetimeofintroductionofcomplementaryfood:aprospectivecohortstudyinruralSenegal,WestAfric
KirstenBSimondon,ValérieDelaunay,AldioumaDiallo,EricElgueroandFrançoisSimondon1FromtheDepartmentsofEpidemiologyandPrevention(KBS,AD,EE,andFS)andReproductiveHealth,FertilityandDevelopment(VD),InstitutdeRecherchepourleDéveloppement,Montpellier,France,andPopulationandHealthResearch...
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LackofhemoglobinresponsetoironsupplementationinanemicMexicanpreschoolerswithmultiplemicronutrientdeficiencies
...andtherelationofthisresponsetoothermicronutrientdeficiencies,anthropometry,morbidity,andusualdietaryintake.Design:RuralMexicanchildrenaged1836mo(n=219)weresupplementedfor12mowitheither20mgFe,20mgZn,bothironandzinc,orplacebo.Childrenwerecategorizedasiron-unsupplemented(IUS;n=109)orironsupplemen...
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CR乳腺鉬靶X線檢查的臨牀應用
...評價CR乳腺鉬靶X線檢查與普通鉬靶X線檢查(以下簡稱CR與MO)在臨牀應用情況的比較。方法隨機選擇110例先後來我科做乳腺檢查患者的MO檢查片和CR檢查片進行對照。結果MO片乳頭、乳暈、皮膚顯示率爲86%,腫塊顯示率爲5%,鈣化...
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Alterationofchoroidalcirculationinthefovealregioninpatientswithtype2diabetes
DepartmentofOphthalmology,AsahikawaMedicalCollege,Asahikawa,JapanABSTRACTAim:Toinvestigatechangesinchoroidalbloodflow(CBF)inthefovealregioninpatientswithtype2diabetes.Methods:LaserDopplerflowmetrywasusedtodeterminetheCBFinthefovealregionin70patientswithtype2diabetesand36ageandsexmatchedhealthysubjec...
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Irondeficiencyininfancy:applyingaphysiologicframeworkforprediction
...09-0406.E-mail:blozoff{at}umich.edu.ABSTRACTBackground:Infantsaged624moareathighriskofirondeficiency.Numerousstudiesworldwidehavesoughttoidentifypredictorsofirondeficiencyinthisagegroup.Objective:Theobjectivesofthestudyweretoapplyaphysiologicmodeltoidentifyriskfactorsforirondeficiencyandtocons...
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Randomizedcomparisonof3typesofmicronutrientsupplementsforhomefortificationofcomplementaryfoodsinGhana:effectsongrowthandmotordevelopment
...,NT,orNBcontaining6,16,and19vitaminsandminerals,respectively,dailyfrom6to12moofage.Weassessedanthropometricstatusat6,9,and12mo;micronutrientstatusat6and12mo;motordevelopmentat12mo;andmorbidityweekly.Infants(n=96)notrandomlyselectedfortheintervention(nonintervention;NI)wereassessedat12mo.Results:Theg...
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Long-termweightlossesassociatedwithprescriptionofhigherphysicalactivitygoals.Arehigherlevelsofphysicalactivityprotectiveagainstweightregai
...ectivedesignwhetherencouraging2500kcalphysicalactivity/wkproducedgreater30-moweightlossesthandidthestandard1000kcalphysicalactivity/wkprescription.Design:Overweightadults(n=202)wererandomlyassignedtoeither18moofstandardbehavioraltreatment(SBT)withanexercisegoalof1000kcal/wkorahighphysicalactivity(HP...
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VitaminAsupplementationselectivelyimprovesthelineargrowthofIndonesianpreschoolchildren:resultsfromarandomizedcontrolledtrial
HamamHadi,RebeccaJStoltzfus,MichaelJDibley,LawrenceHMoulton,KeithPWest,Jr,ChrisLKjolhedeandTonnySadjimin1FromtheDivisionofHumanNutrition,theDepartmentofPublicHealth,theFacultyofMedicine,theUniversityofGadjahMada,Yogyakarta,Indonesia;theDivisionofHumanNutrition,theDepartmentsofInternationalHealthandB...
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Earlyproteinintakeandlaterobesityrisk:whichproteinsourcesatwhichtimepointsthroughoutinfancyandchildhoodareimportantforbodymassindexand
...stphalia,Germany,andbyaresearchgrantfromtheInternationalFoundationforthePromotionofNutritionResearchandNutritionEducation(toALBG).3Reprintsnotavailable.AddresscorrespondencetoALBGünther,NutritionandHealthUnit,ResearchInstituteofChildNutrition,Heinstueck11,44225Dortmund,Germany.E-mail:guenther{a...
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全血法與稀釋法測血中WBC、RBC、Hb、PLT、GR、LY、MO
...PLT、LY無明顯變化,全血法中的WBC、RBC、Hb、PLT、GR、LY、MO也不隨檢測時間延長而改變。結論稀釋法檢測血常規應在25min前檢測完。【關鍵詞】血常規稀釋法;檢驗結果;放置時間實驗結果的誤差可以來自分析前、分析中,隨着儀...
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Zincsupplementationdoesnotaffectgrowth,morbidity,ormotordevelopmentofUStermbreastfedinfantsat410moofage
...:Theobjectiveofthisstudywastoexaminetheeffectofzincsupplementationongrowth,morbidity,andmotordevelopmentinhealthy,term,breastfedinfants.Design:Weconductedarandomizeddouble-blindinterventioncomparingzincsupplementation(5mg/daszincsulfate)withplaceboinbreastfedinfantsaged410mo.Growthandindexesof...
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生化與細胞所揭示STE20家族激酶MST4的激活機制
...趙允研究組的最新研究成果——StructureoftheMST4inComplexwithMO25ProvidesInsightsintoItsActivationMechanism。該研究闡述了支架蛋白MO25對STE20家族激酶MST4的激活機制。MST4屬於STE20激酶GCKIII亞家族,在細胞極性、增值、轉化與遷移等過程中發揮重...
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VitaminAsupplementationinchildrenwithpoorvitaminAandironstatusincreaseserythropoietinandhemoglobinconcentrationswithoutchangingtotalbodyi
...,Zürich,Switzerland(MBZ,RB,FR,CZ,andRFH),andTheMinistryofHealth,Rabat,Morocco(ADandNC).2SupportedbytheThrasherResearchFund(SaltLakeCity,UT),theFoundationforMicronutrientsinMedicine(Rapperswil,Switzerland),andtheSwissFederalInstituteofTechnology(Zürich,Switzerland).VitaminAsupplementswerepr...
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Effectsofchroniccopperexposureduringearlylifeinrhesusmonkeys
...astoassesscopperretention,livercoppercontent,andliverfunctionininfantrhesusmonkeysfedinfantformulacontaining6.6mgCu/L.Design:Frombirthto5moofage,infantrhesusmonkeyswerefedformulathatwassupplementedwithcopper(0.6mgCu/L;n=5)ornotsupplemented(n=4).Inallanimals,weightandcrown-rumplength(byanthropometry)...
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Optimaldurationofexclusivebreastfeeding:whatistheevidencetosupportcurrentrecommendations?
MarySFewtrell,JaneBMorgan,ChristopherDuggan,GeirGunnlaugsson,PatriciaLHibberd,AlanLucasandRonaldEKleinman1FromtheMRCChildhoodNutritionResearchCentre,InstituteofChildHealth,London,UnitedKingdom(MSFandAL);theSchoolofBiomedicalandMolecularSciences,UniversityofSurrey,Guildford,UnitedKingdom(JBM);theClin...
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Lowerantioxidantcapacityandelevatedp53andp21maybealinkbetweengenderdisparityinrenaltelomereshortening,albuminuria,andlongevity
...ge,UnitedKingdomABSTRACTItiswelldocumentedthatfemaleslivelongerthanmalesandmorerenaldamageoccursinmales.However,theunderlyingmechanismsarenotfullyunderstood.Theaimofthisstudywastodefineagingeffectsonalbuminuriaandkidneytelomerelengthfrommaleandfemaleratsandtodeterminemechanisms,whichmayexplainanyobs...
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過氟-N-辛烷在視網膜巨大裂孔手術中的應用
...的46例巨大視網膜裂孔患者的臨牀資料.結果:術後隨訪6mo~36mo(平均15.6mo),視網膜最終復位38例(83%),視力改善者40例(87%).結論:採用PFnO液治療可明顯提高視網膜巨大裂孔手術的成功率. 0 引言 視網膜巨大裂孔是...
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Adult-onsetcalorierestrictiondelaystheaccumulationofmitochondrialenzymeabnormalitiesinagingratkidneytubularepithelialcells
【摘要】Adult-onsetcalorierestriction(A-CR)isanexperimentalmodeloflifeextensionandhealthyaginglessexplored,comparedwithcalorierestrictionbegunatearlyages,butonemorerealisticforhumanapplication.WeexaminedtheeffectofA-CRontheagingratkidneywithrespecttocommonstructuralage-dependentchangesandtheaccu...
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Predictorsofserumferritinandserumsolubletransferrinreceptorinnewbornsandtheirassociationswithironstatusduringthefirst2yoflife
...n,theNorwegianWomen‘sPublicHealthAssociation,AndersJahre‘sFundforthePromotionofScience,TheEckboFoundation,SCAHygieneProductsAS,andAstraZenecaAS.3Reprintsnotavailable.AddresscorrespondencetoGHay,DepartmentofNutrition,UniversityofOslo,POBox1046Blindern,N-0316Oslo,Norway.E-mail:gry.hay{at}medisin.u...
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Physicalactivityandweightloss:doesprescribinghigherphysicalactivitygoalsimproveoutcome?
...exercisepartnersintothestudy,personalcounselingfromanexercisecoach,andsmallmonetaryincentives.Results:TheHPAtreatmentgroupreportedachievinghighermean(±SD)physicalactivitylevelsthandidtheSBTgroupat6mo(EEof2399±1571kcal/wkcomparedwith1837±1431kcal/wk),12mo(EEof2249±1751kcal/wkcompa...
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Extentofthermalprocessingofinfantformulaaffectscopperstatusininfantrhesusmonkeys
...5616-8669.E-mail:bllonnerdal{at}ucdavis.edu.ABSTRACTBackground:Infantrhesusmonkeysareexcellentmodelsinwhichtostudytheeffectofinfantformulasontraceelementabsorptionandstatus.Infantsfedpowderedformulafrombirthexhibitnormalgrowthandhavebloodvariablessimilartothoseofbreast-fedinfants.Objectives:Theobjec...
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Docolonicshort-chainfattyacidscontributetothelong-termadaptationofbloodlipidsinsubjectswithtype2diabetesconsumingahigh-fiberdiet?
...,UniversityofToronto(TMSW,KBS,JAV,andEBT);theClinicalNutritionandRiskFactorModificationCentreandtheDivisionofEndocrinologyandMetabolism,StMichael‘sHospital,Toronto(TMSW);andKelloggCompany,BattleCreek,MI(MIM).2SupportedbygrantsfromtheKelloggCompanyandtheMedicalResearchCouncilofCanada(no.UI-13990).3...
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Breastfeeding,introductionofcomplementaryfoods,andadiposityat5yofage
...STRACTBackground:Althoughdual-energyX-rayabsorptiometry(DXA)isconsideredthemostaccuratemeasureofadiposityinchildren,ithasrarelybeenusedtoexaminetherelationbetweeninfantfeedingandadiposityduringchildhood.Objective:Theobjectivewastoascertainwhetheradiposityatage5ywasrelatedtobreastfeeding,tothetimingo...
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Ironabsorptioninbreast-fedinfants:effectsofage,ironstatus,ironsupplements,andcomplementaryfoods
...mlyassignedtoreceiveeither1)ironsupplements(1mg·kg-1·d-1)from4to9moofage,2)placebofrom4to6moandironsupplementsfrom6to9mo,or3)placebofrom4to9mo.Infantswereexclusivelybreast-fedto6moandpartiallybreast-fedto9moofage.Ironabsorptionwasassessedbygiving58Fewithmother‘smilkat6and9mo.Bloodsamples...
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Complementaryfeeding:clinicallyrelevantfactorsaffectingtimingandcomposition
....E-mail:nancy.krebs{at}uchsc.edu.ABSTRACTExclusivebreastfeedingforthefirst6mooflifefollowedbyoptimalcomplementaryfeedingarecriticalpublichealthmeasuresforreducingandpreventingmorbidityandmortalityinyoungchildren.Clinicalfactors,suchasbirthweight,prematurity,andillness,thataffecttheironandzincrequire...
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Catch-upgrowthinsmall-for-gestational-ageterminfants:arandomizedtrial
MarySFewtrell,RuthMorley,RebeccaAAbbott,AtulSinghal,TerenceStephenson,UnaMMacFadyen,HelenaClementsandAlanLucas1FromtheMRCChildhoodNutritionResearchCentre,InstituteofChildHealth,London;theMenziesCentreforPopulationResearch,Tasmania,Australia;theClinicalEpidemiologyBiostatisticsUnit,theDepartmentofPae...