MitochondrialNADP+-DependentIsocitrateDehydrogenaseProtectsCadmium-InducedApoptosis
...mationofoxidizedglutathione(GSSG)andregenerationofGSHbycouplingwithNADPHandGSSGreductase,termedtheGSH-regeneratingsystem(GanandWells,1986).ThesecharacteristicinteractionsofGrxwithGSHdistinguishitfromTrx,whichfavorsintramoleculardisulfidesubstratesandisturnedoverbyNADPHandthioredoxinreductaseindepend...