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植物酶類源自非酶物質
...都是從蛋白質進化而來。來自薩克生物研究學院的JosephP.Noel及同伴將注意力集中在尋找一種新陳代謝酶類的進化過程上,這種酶的前身僅是一類無任何活性的蛋白質。這種酶被稱爲查爾酮異構酶(chalconeisomerase,CHI),它對一類...
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MolecularCloningExpressionSelf-Assembly,Antigenicity,andSeroepidemiologyofaGenogroupIINorovirusIsolatedinFrance
...andECOS-Nord(no.CF99S01). REFERENCESTopAbstractTextReferencesAndo,T.,J.S.Noel,andR.L.Fankhauser.2000.GeneticclassificationofNorwalk-likeviruses.J.Infect.Dis.181(Suppl.2):S336-S348.Belliot,G.,J.S.Noel,J.F.Li,Y.Seto,C.D.Humphrey,T.Ando,R.I.Glass,andS.S.Monroe.2001.Characterizationofcapsidgenes,expre...
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MultiprefecturalSpreadofGastroenteritisOutbreaksAttributabletoaSingleGenogroupIINorovirusStrainfromaTouristRestaurantinNagasaki,Japan
...edbyNVsintouriststravelingbybusbetweentheUnitedStatesandCanada.Furthermore,Noeletal.(25)reportedthatNVoutbreaksduetoasinglevirusoccurredinsevencountriesonfivecontinentsduringthe1995-1996season,suggestingthatthecirculationofthestrainsmightinvolvepatternsoftransmissionnotpreviouslyconsidered.Food-born...
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MolecularEpidemiologyofCalicivirusesDetectedinSporadicandOutbreakCasesofGastroenteritisinFrancefromDecember1998toFebruary2004
...cription-PCRandSouthernhybridization.J.Clin.Microbiol.33:64-71.Ando,T.,J.S.Noel,andR.L.Fankhauser.2000.Geneticclassificationof“Norwalk-likeviruses.“J.Infect.Dis.181(Suppl.2):S336-S348.Bon,F.,K.Balay,L.LeCoustumier,P.Megraud,P.LeCann,A.Gallay,P.Pothier,andE.Kohli.Waterborneoutbreakofacutegastroen...
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匹維溴胺治療腸易激綜合徵的臨牀觀察
...腸易激綜合徵有關的腹痛、排便紊亂、腸道不適等症狀。Noel[11]報道了一個大規模、公開的多中心臨牀觀察,評估了匹維溴胺對IBS的治療效果。1537例IBS患者應用匹維溴胺治療,結果表明匹維溴胺能顯著改善IBS患者的胃腸功能...
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植物生產脂肪酸的機制
...包括ω-3脂肪酸等。ω-3脂肪酸是重要的植物和人類福祉。Noel和同事們的研究表明查耳酮異構酶編碼基因的變化會對植物生殖有變化。由於查爾酮異構酶的基本研究已過了十年,現在正出效益的時候,研究人員認爲查爾酮異構酶蛋...
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BroadlyReactiveNestedReverseTranscription-PCRUsinganInternalRNAStandardControlforDetectionofNorovirusesinStoolSamples
...echniqueandrequiresexpertiseinrecognizingthesmallviralparticles(12),andimmunoelectronmicroscopy,whichneedsantiseraormonoclonalantibodiesavailableonlyinreferencelaboratories(2).Onlyinthepastdecadehastheknowledgeofthenucleotidesequenceandthegenomicorganizationofseveralstrainsofnorovirusesledtothedevel...
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GeneticAnalysisofNorovirusesinChibaPrefecture,Japan,between1999and2004
...seasesfromtheMinistryofHealth,LaborandWelfareofJapan.REFERENCESAndo,T.,J.S.Noel,andR.L.Fankhauser.2000.Geneticclassificationof“Norwalk-likeviruses.“J.Infect.Dis.181(Suppl.2):S336-S348.Berke,T.,B.Golding,X.Jiang,D.W.Cubitt,M.Wolfaardt,A.W.Smith,andD.O.Matson.1997.Phylogeneticanalysisofthecalicivi...
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Adose-dependentrequirementfortheprolinemotifofCD28incellularandhumoralimmunityrevealedbyatargetedknockinmutant
...atoryrequirementsinCD28-deficientmice.Science.261:609–612.Green,J.M.,P.J.Noel,A.I.Sperling,T.L.Walunas,G.S.Gray,J.A.Bluestone,andC.B.Thompson.1994.AbsenceofB7-dependentresponsesinCD28-deficientmice.Immunity.1:501–508.Noel,P.J.,L.H.Boise,J.M.Green,andC.B.Thompson.1996.CD28costimulationpreventscel...
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CharacterizationofNewRecombinantNoroviruses
...virusamongsnowmobilers—Wyoming,2001.J.Infect.Dis.187:303-306.Ando,T.,J.S.Noel,andR.L.Fankhauser.2000.Geneticclassificationof“Norwalk-likeviruses.“J.Infect.Dis.181(Suppl.2):S336-S338.Bon,F.,H.Giraudon,C.Sancey,C.Barranger,M.Joannes,P.Pothier,andE.Kohli.2004.Developmentandevaluationofanewcommerc...
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MolecularEpidemiologyofNorovirusInfectionsinStockholm,Sweden,duringtheYears2000to2003:AssociationoftheGGIIbGeneticClusterwithInfectionin
...esbysolid-phaseimmuneelectronmicroscopy.Arch.Virol.135:217-226.Ando,T.,J.S.Noel,andR.L.Fankhauser.2000.Geneticclassificationof“Norwalk-likeviruses.“J.Infect.Dis.181(Suppl.2):S336-S348.Büchen-Osmond,C.(ed.).2003.Caliciviridae.InICTVdB—theuniversalvirusdatabase,version3.ColumbiaUniversity,Oracl...
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UseofaHeminestedReverseTranscriptasePCRAssayforDetectionofAstrovirusinEnvironmentalSwabsfromanOutbreakofGastroenteritisinaPediatricPrim
...dbyreversetranscriptase-polymerasechainreaction.J.Infect.Dis.172:1437-1444.Noel,J.,andD.Cubitt.1994.IdentificationofastrovirusserotypesfromchildrentreatedattheHospitalsforSickChildren,London1981-93.Epidemiol.Infect.113:153-159.Noel,J.S.,T.W.Lee,J.B.Kurtz,R.I.Glass,andS.S.Monroe.1995.Typingofhumanast...
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ComparisonofaNewCommercialTest,GLABRATARTT,withaDipstickTestforRapidIdentificationofCandidaglabrata
...laboratory:phenotypicalmethods.Med.Mycol.39:9-33.Freydiere,A.M.,F.Parant,F.Noel-Baron,M.Crepy,A.Treny,H.Raberin,A.Davidson,andF.C.Odds.2002.IdentificationofCandidaglabratabya30-secondtrehalasetest.J.Clin.Microbiol.40:3602-3605.Freydiere,A.M.,R.Robert,C.Ploton,A.Marot-Leblond,F.Monerau,andF.Vandenesc...
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PrevalenceofNorovirusamongVisitorsfromtheUnitedStatestoMexicoandGuatemalaWhoExperienceTraveler‘sDiarrhea
...eler‘sdiarrhea.N.Engl.J.Med.328:1821-1827.Fankhauser,R.L.,S.S.Monroe,J.S.Noel,C.D.Humphrey,J.S.Bresee,U.D.Parashar,T.Ando,andR.I.Glass.2002.Epidemiologicandmoleculartrendsof“Norwalk-likeviruses“associatedwithoutbreaksofgastroenteritisintheUnitedStates.J.Infect.Dis.186:1-7.Fankhauser,R.L.,J.S.N...
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左心衰竭右室壓力訓練動物實驗的病理學觀察
...練,是爲了解右心室是否可以適應高壓環境。本研究採用Noel應用的肺動脈環縮法來實現右心室壓力超負荷[5],有文獻報道,在肺動脈環縮後96h右心室就能夠肥厚[6],肺動脈環縮6天后右心室心肌細胞直徑增大,右心室壁厚...
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質子放射治療與顱底脊索瘤
...與光子束的混合照射,可進一步改善顱底脊索瘤的預後。Noel報道34例顱底脊索瘤採用光子束照射,剩餘1/3劑量採用質子束縮野加量照射,總劑量60~70cGE。GTV平均總劑量限制在67cGE。中位隨訪30.5個月(2~56個月),脊索瘤的3年局部...
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OutbreaksofGastroenteritisThatOccurredduringSchoolExcursionsinKoreaWereAssociatedwithSeveralWaterborneStrainsofNorovirus
...M.A.Drebot,S.A.Jenkerson,E.Funk,M.D.Sobsey,O.D.Simmons,S.S.Monroe,T.Ando,J.Noel,M.Petric,J.P.Middaugh,andJ.S.Spika.1997.Outbreakofviralgastroenteritisduetoacontaminatedwell.JAMA278:563-568.Boccia,D.,A.E.Tozzi,B.Cotter,C.Rizzo,T.Russo,G.Buttinelli,A.Caprioli,M.L.Marziano,andF.M.Ruggeri.2002.Water-bor...
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AroleforIgGimmunecomplexesduringinfectionwiththeintracellularpathogenLeishmania
...facesofmacrophageactivation.J.Leukoc.Biol.73:209–212.Sutterwala,F.S.,G.J.Noel,R.Clynes,andD.M.Mosser.1997.Selectivesuppressionofinterleukin-12inductionaftermacrophagereceptorligation.J.Exp.Med.185:1977–1985.Sutterwala,F.S.,G.J.Noel,P.Salgame,andD.M.Mosser.1998.Reversalofproinflammatoryresponsesb...
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StructuralbasisforthefunctionandregulationofthereceptorproteintyrosinephosphataseCD45
...sphatase.Biochemistry.38:914–922.Bilwes,A.M.,J.denHertog,T.Hunter,andJ.P.Noel.1996.Structuralbasisforinhibitionofreceptorprotein-tyrosinephosphatase-alphabydimerization.Nature.382:555–559.Desai,D.M.,J.Sap,J.Schlessinger,andA.Weiss.1993.Ligand-mediatednegativeregulationofachimerictransmembranerec...
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ApplicationofaMolecularPanelToDemonstrateEnterotropicVirusSheddingbyHealthyandHumanImmunodeficiencyVirus-InfectedPatients
...nreactionforrapiddiagnosisofenterovirusinfection.J.Virol.Methods48:155-166.Noel,J.S.,T.W.Lee,J.B.Kurtz,R.I.Glass,andS.S.Monroe.1995.Typingofhumanastrovirusesfromclinicalisolatesbyenzymeimmunoassayandnucleotidesequencing.J.Clin.Microbiol.33:797-801.Okitsu-Negishi,S.,T.A.Nguyen,T.G.Phan,andH.Ushijima....
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MulticenterEvaluationofaCandidaalbicansPeptideNucleicAcidFluorescentInSituHybridizationProbeforCharacterizationofYeastIsolatesfromBloodCu
...laboratory:phenotypicalmethods.Med.Mycol.39:9-33.Freydiere,A.M.,F.Parant,F.Noel-Baron,M.Crepy,A.Treny,H.Raberin,A.Davidson,andF.C.Odds.2002.IdentificationofCandidaglabratabya30-secondtrehalasetest.J.Clin.Microbiol.40:3602-3605.Gutierrez,J.,P.Morales,M.A.Gonzalez,andG.Quindos.2002.Candidadubliniensis...
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NorovirusesasaCauseofTraveler‘sDiarrheaamongStudentsfromtheUnitedStatesVisitingMexico
...,randomizedtrial.Ann.Intern.Med.106:216-220.Fankhauser,R.L.,S.S.Monroe,J.S.Noel,C.D.Humphrey,J.S.Bresee,U.D.Parashar,T.Ando,andR.I.Glass.2002.Epidemiologicandmoleculartrendsof“Norwalk-likeviruses“associatedwithoutbreaksofgastroenteritisintheUnitedStates.J.Infect.Dis.186:1-7.Gorbach,S.L.,B.H.Kean...
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RapidIdentificationofCandidaglabratawithaNewCommercialTestGLABRATARTT
...boratory:phenotypicalmethods.Med.Mycol.39:9-33.Freydière,A.-M.,F.Parant,F.Noel-Baron,M.Crepy,A.Treny,H.Raberin,A.Davidson,andF.C.Odds.2002.IdentificationofCandidaglabratabya30-secondtrehalasetest.J.Clin.Microbiol.40:3602-3605.Fricker-Hidalgo,H.,S.Orenga,B.Lebeau,H.Pelloux,M.P.Brenier-Pinchart,P.Amb...
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ComparisonoftheCOBASAMPLICORMTBandBDProbeTecETAssaysforDetectionofMycobacteriumtuberculosisinRespiratorySpecimens
...bacteriumtuberculosiscomplex.Mol.Cell.Probes7:395-404.Thierry,D.,A.Brisson-Noel,V.Vincent-Levy-Frebault,S.Nguyen,J.-L.Guesdon,andB.Gicquel.1990.CharacterizationofaMycobacteriumtuberculosisinsertionsequence,IS6110,anditsapplicationindiagnosis.J.Clin.Microbiol.28:2668-2673.Thomsen,V.O.,A.Kok-Jensen,M....
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Self-AssemblyoftheRecombinantCapsidProteinofaBovineNorovirus(BoNV)intoVirus-LikeParticlesandEvaluationofCross-ReactivityofBoNVwithHumanN
...a/269/93/US,andHu/Noro/II/MD145/87/US,didnotreactwiththeBoNVGIII/2reagents.Noeletal.(41)reportedhomologousimmuneresponsestoNorwalkvirusinpatientsinfectedwithothernorovirusGIstrainswithasmuchas38.5%aminoaciddivergenceintheN-terminalsequenceofthecapsidgene.However,homologousimmuneresponsestotheToronto...
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TestingforInductionofClindamycinResistanceinErythromycin-ResistantIsolatesofStaphylococcusaureus
...HealthServiceortheU.S.DepartmentofHealthandHumanServices.REFERENCESBrisson-Noel,A.,P.Delrieu,D.Samain,andP.Courvalin.1988.InactivationoflincosaminideantibioticsinStaphylococcus.IdentificationoflincosaminideO-nucleotidyltransferasesandcomparisonofthecorrespondingresistancegenes.J.Biol.Chem.263:15880-...
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Eotaxin-3andauniquelyconservedgene-expressionprofileineosinophilicesophagitis
...sinophiliainchildrenwithdysphagia.J.Pediatr.Gastroenterol.Nutr.37::498-503.Noel,R.J.,Putnam,P.E.,andRothenberg,M.E.2004..Eosinophilicesophagitis.N.Engl.J.Med.351::940-941.Kelly,K.J.etal.1995..Eosinophilicesophagitisattributedtogastroesophagealreflux:improvementwithanaminoacid-basedformula.Gastroente...
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GelsolinSecretioninInterleukin-4–treatedBronchialEpitheliaandinAsthmaticAirways
...nbronchialepithelialcells.AmJPhysiolLungCellMolPhysiol2002;282:L226–L236.Noel-GeorisI,BernardA,FalmagneP,WattiezR.Databaseofbronchoalveolarlavagefluidproteins.JChromatogrBAnalytTechnolBiomedLifeSci2002;771:221–236.MagiB,BiniL,PerariMG,FossiA,SanchezJC,HochstrasserD,PaesanoS,RaggiaschiR,SantucciA...
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第一節 免疫細胞化學技術在腎臟疾病中的應用範圍
...樣方法亦可測定腎小球中沉積的免疫複合物內的IgG亞類。Noel報道,不同腎炎時腎小球內沉積之IgG亞類有所不同。原發性膜性腎炎之沉積物爲Igg1和IgG4,狼瘡性腎炎之沉積物爲IgG1、IgG2和IgG3。 3.血清中Tamm-Horsfall糖蛋白(THP)...
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EtiologyofDiarrheainYoungChildreninDenmark:aCase-ControlStudy
...rotypes.Curr.Microbiol.3:95-99.Dennehy,P.H.,S.M.Nelson,S.Spangenberger,J.S.Noel,S.S.Monroe,andR.I.Glass.2001.Aprospectivecase-controlstudyoftheroleofastrovirusinacutediarrheaamonghospitalizedyoungchildren.J.Infect.Dis.184:10-15.deWit,M.A.,M.P.Koopmans,L.M.Kortbeek,W.J.Wannet,J.Vinje,F.vanLeusden,A.I...