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Ratioofoleictopalmiticacidisadietarydeterminantofthrombogenicandfibrinolyticfactorsduringthepostprandialstateinmen
...ioofoleictopalmiticacid[andthatofmonounsaturatedtosaturatedfattyacids(MUFA:SFA)]inthedietaffectspostprandialconcentrationsoftriacylglycerols,tissuefactor(TF),fibrinogen,tissue-typeplasminogenactivator(t-PA),andplasminogenactivatorinhibitor1(PAI-1).Design:Westudiedtheeffectsofdietsenrichedinoliveoil(...
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不同糖耐量人羣血漿脂肪酸譜與胰島素抵抗
...NGT、IGT和DM組依次升高,差異有顯著性;血漿飽和脂肪酸(SFA)從NGT、IGT、DM亞組依次升高;NGT組的多不飽和脂肪酸(PUFA)與SFA的比率高於IGT組和DM組;血漿軟脂酸、花生四烯酸、二十二烷酸、SFA與IAI呈負相關;PUFA/SFA與IAI呈正相關。...
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不同糖耐量人羣血漿脂肪酸譜與胰島素抵抗
...NGT、IGT和DM組依次升高,差異有顯著性;血漿飽和脂肪酸(SFA)從NGT、IGT、DM亞組依次升高;NGT組的多不飽和脂肪酸(PUFA)與SFA的比率高於IGT組和DM組;血漿軟脂酸、花生四烯酸、二十二烷酸、SFA與IAI呈負相關;PUFA/SFA與IAI呈正相關。...
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OSAHS的脂肪積聚,瘦素及高碳酸血癥
...在論證脂肪堆積的部位如內臟脂肪積聚和皮下脂肪積聚(SFA)是否會引起肺換氣不足,循環瘦素水平是否參與了OSAHS中常見的肺換氣不足的發病機理。他們對106名血碳酸正常,79名高碳酸血癥的OSAHS患者用腹部CT測量了VFA和SFA,同...
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Macronutrientintakeandglycemiccontrolinapopulation-basedsampleofAmericanIndianswithdiabetes:theStrongHeartStudy
...ely).Nosignificantassociationwasfoundbetweenpolyunsaturatedfattyacidsortransfattyacidsandglycemiccontrolinthispopulation.Conclusions:ThesedatasuggestthatahigherconsumptionoftotalfatandsaturatedandmonounsaturatedfattyacidsandalowerintakeofcarbohydratesareassociatedwithpoorglycemiccontrolindiabeticAme...
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外周動脈病的目前治療方法---導管介入(2)
...者中,閉塞比狹窄更常見。二大技術進展方便了股淺動脈(SFA)閉塞的治療,甚至(10cm)長段或慢性閉塞也有可能再通。第1是使用了親水性導絲。第二是使用溶栓治療,這一方法已證明有效,甚至用於一些慢性完全閉塞的患者,因爲下肢動...
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Polymorphismexon1variantatthelocusofthescavengerreceptorclassBtypeIgene:influenceonplasmaLDLcholesterolinhealthysubjectsduringthecon
.../2)].Bothgroupsconsumed3dietslasting4wkeach.Thefirstwasasaturatedfattyacid(SFA)richdiet(38%fat,20%SFA),whichwasfollowedbyacarbohydrate(Cho)richdiet(30%fat,10%SFA,55%carbohydrate)oramonounsaturatedfattyacid(MUFA),oliveoilrichdiet(38%fat,22%MUFA)accordingtoarandomizedcrossoverdesign....
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TCT2006試驗薈萃(三)
...架柱的藥物濃度最高,而此處的癒合也是最重要的問題。SFA:支架斷裂?SIROCCO(熱風)?非植入性的局部藥物分佈不需要持續性釋放。因此,我們不禁要問:是否需要持續的藥物釋放?第一個研究:IopromidePaclitaxe,(JACC,2003;42:1415-...
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外周動脈病經皮介入治療進展
...或閉塞在經血管造影考慮血運重建的患者中,股淺動脈(SFA)與膕動脈閉塞比狹窄更常見。下肢動脈閉塞典型特徵爲長段凝膠樣血栓附及在高度粥樣硬化的病變上。由於介入技術的進展方便了股淺動脈(SFA)閉塞的治療,甚至長段(...
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鐵蛋白可以提示全身脂肪含量
...查了248名日本受試者的內臟脂肪區(VFA)和皮下脂肪區(SFA),其中140人患有2型糖尿病,其他人健康狀況良好。爲了排除結果受脂肪肝影響的可能性,研究沒有招募既往有大量飲酒史的受試者。根據研究結果,科學家們發現血...
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糖調節異常患者血中游離脂肪酸水平與動脈粥樣硬化的關係
...率。結果(1)與NGT組比較,IGR和T2DM組血清FFA和飽和脂肪酸(SFA)水平明顯升高(P<0.05);(2)多不飽和脂肪酸(PUSFA)水平降低(P<0.01);IMT增厚,動脈斑塊的發病率增高(P<0.05);(3)IMT厚度與血清SFA水平呈正相關,與PUSFA水平呈負相關。可見...
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Differencesinglucose-dependentinsulinotrophicpolypeptidehormoneandhepaticlipaseinsubjectsofsouthernandnorthernEurope:implicationsforpostpran
...testmealsofidenticalmacronutrientcompositionbutdifferentsaturatedfattyacid(SFA)andmonounsaturatedfattyacid(MUFA)contentsonpostprandialGIP,insulin,theratioofincrementaltriacylglyceroltoapolipoproteinB-48(amarkerofchylomicronsize),andtheactivityofpostheparinlipases.Results:FastingandpostprandialGIPcon...
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Contributionofpostprandiallipemiatothedietaryfat-mediatedchangesinendogenouslipoprotein-cholesterolconcentrationsinhumans
...l-richlipoproteins(TRLs).Objective:Wehypothesizedthatthesaturatedfattyacid(SFA)mediatedincreaseandthepolyunsaturatedfattyacid(PUFA)mediateddecreaseinendogenouslipoproteincholesterolarepromotedbypostprandialTRLs.Design:Weperformeda16-dcrossoverdietstudytoexaminetheeffectofPUFA-rich[ratioo...
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MacrophagecholesteroleffluxelicitedbyhumantotalplasmaandbyHDLsubfractionsisnotaffectedbydifferenttypesofdietaryfattyacids
...calorieintakebeintheformoffat,wecomparedtheresultsoftheintakeof30%ofenergyasfatindietsenrichedwithtrans,polyunsaturated,orsaturatedFAs.ThesedietaryeffectsonthecompositionandabilityofHDL2,HDL3,andtotalplasmatoeffluxcholesterolfrommouseperitonealmacrophagesthatpreviouslywereloadedwithLDL-acetylated14C...
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ApolipoproteinEgenepromoter219GTpolymorphismincreasesLDL-cholesterolconcentrationsandsusceptibilitytooxidationinresponsetoadietrichin
...0TT)completed3dietaryperiods,eachlasting4wk.Thefirstwasasaturatedfattyacid(SFA)-richdiet[38%fat20%SFAand12%monounsaturatedfattyacid(MUFA)and47%carbohydrates(CHO)],whichwasfollowedbyaCHO-richdiet(30%fat10%SFAand12%MUFAand55%CHO)oraMUFA-richdiet(38%fat10%SFAand22%MUFA...
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ExtendedVirulenceGenotypesandPhylogeneticBackgroundofEscherichiacoliIsolatesfromPatientswithCystitis,Pyelonephritis,orProstatitis
...rofuniqueVFsdetected,withadjustmentformultipledetectionofthepap(Pfimbriae),sfa/foc(S/F1Cfimbriae),andkpsII(group2capsule)operons.TheE.coliphylogeneticgroupoforigin(A,B1,B2,orD),asinitiallydefinedonthebasisofmultilocusenzymeelectrophoresis[15],wasdeterminedbyuseofa3-locusPCR-basedmethod[12].Eachisola...
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Flow-MediatedDilatationIsImpairedbyaHigh–SaturatedFatDietbutNotbyaHigh-CarbohydrateDiet
...drate(CARB)dietimpairedendothelialvasodilationcomparedwithhighsaturatedfat(SFA),monounsaturatedfat(MUFA),orpolyunsaturatedfat(PUFA)diets.MethodsandResults—Fortyhealthysubjectswererandomlycrossedoverto4,3-weekisocaloricdietshighinPUFA,MUFA,orSFA,containingatleast25goftherelevantfatoralow-fat,CARB,h...
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四、近交系動物在免疫研究中的應用
...途徑。 Katz過去證明在小鼠中有變態反應抑制因子(SFA)可抑制小鼠IgE的應答。在此次討論中它以大量的實驗證據證實了人SFA的存在。SFA能選擇性地抑制IgE抗體合成。人SFA來自雙向混合淋巴細胞培養(MLR)的上清液。測定系...
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Plasmafattyacidcompositionisassociatedwiththemetabolicsyndromeandlow-gradeinflammationinoverweightadolescents
...aredwithoverweightadolescents,normal-weightadolescentshadlowersaturatedFAs(SFAs)inbothphospholipids(P0.001)andCEs(P0.01)andhigherdocosahexaenoicacidinphospholipids(P0.001).Inoverweightsubjects,FAcompositionwasassociatedwithMSfeaturesindependentofbodyfat.TheoddsratiosofMSfora0.1increaseintheratioofpo...
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Carbohydraterestrictioniseffectiveinimprovingatherogenicdyslipidemiaevenintheabsenceofweightloss
...thesubjectsreceivingagreaterpercentage(15%)ofenergyfromsaturatedfattyacids(SFA).Thenegativeconclusionstandsinstarkcontrasttothedatainthepaperthatshowthatcarbohydraterestrictioniseffectiveforimprovingatherogenicdyslipidemiaevenintheabsenceofweightloss.Thereasonmostmarkerswerelessresponsivetoweightlos...
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候鳥在葡萄酒釀造中起着重要的作用
...349只候鳥,然後將他們分類標記,並測量了皮下脂肪量(SFA)。然後採用基因方法分析酵母種類。 結果 在32.66%的候鳥身上發現了野生酵母。在鶲科、鶇科、雀科這三種鳥類身上的酵母量最大。 通過基因分析共找到了125...
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DietarycholesteroldoesnotincreasebiomarkersforchronicdiseaseinapediatricpopulationfromnorthernMexico
...(20).Viewthistable:TABLE2.Intakesofcarbohydrate;protein;totalfat;saturated(SFA),polyunsaturated(PUFA),andmonounsaturated(MUFA)fattyacids;dietarycholesterol;dietaryfiber;andvitaminEofhyper-andhyporespondersduringtheEGGandSUBperiods1Inregardtoresponseclassification,theamountoftotalcaloriesconsumedwasn...
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Fattyacidcompositionofskeletalmusclereflectsdietaryfatcompositioninhumans
...andomlyassignedtodietscontainingahighproportionofeithersaturatedfattyacids(SFAs)[totalfat,36%ofenergy;SFAs,18%ofenergy;monounsaturatedfattyacids(MUFAs),10%ofenergy]orMUFAs(totalfat,35%ofenergy;SFAs,9%ofenergy;MUFAs,19%ofenergy)for3mo.Withineachdietgroup,therewasasecondrandomassignmenttosupplementati...
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Dietarycis-monounsaturatedfattyacidsandmetaboliccontrolintype2diabetes
...ctiveoffattyacidcomposition.LimitedexperimentalevidencesuggeststhatMUFAdietsfavorablyinfluencebloodpressure,coagulation,endothelialactivation,inflammation,andthermogeniccapacity.Energy-controlledhigh-MUFAdietsdonotpromoteweightgainandaremoreacceptablethanlow-fatdietsforweightlossinobesesubjects.Thus...
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ReplytoPMarckmann
...;5.Kris-EthertonPM,fortheDELTAinvestigators.Effectsofreplacingsaturatedfat(SFA)withmonounsaturatedfat(MUFA)orcarbohydrate(CHO)onplasmalipidsandlipoproteinsinindividualswithmarkersforinsulinresistance.FASEBJ1996;10:2666.Yu-PothS,ZhaoG,EthertonT,NaglakM,JonnalagaddaS,Kris-EthertonPM.EffectsoftheNation...
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Dietaryandplasmalipid,lipoprotein,andapolipoproteinprofilesamongelderlyHispanicsandnon-Hispanicsandtheirassociationwithdiabetes
...nergyintakefromtotalcarbohydrates,totalfat[monounsaturated(MUFA),saturated(SFA),andpolyunsaturated(PUFA)fattyacids],andalcohol.Cholesterol(mg)intakewasalsoevaluated.Aphysicalactivityscorewascalculatedbymultiplyingthetimespentindifferentactivitiesbycorrespondingweightingfactorsthatparalleltheincrease...
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Fattyacidsaturationofthedietandplasmalipidconcentrations,lipoproteinparticleconcentrations,andcholesteroleffluxcapacity
...teenwomenand24menfollowedinthesamesequence4dietscontaining35%oftotalenergyasfat.Thesaturatedfatdietcontained17%palmoil;themonounsaturatedfatdiet,20.9%oliveoil;then-6polyunsaturatedfatdiet,12.5%sunfloweroil;andthen-3polyunsaturatedfatdiet,sunfloweroilsupplementedwith44.5gfishoil/d.Eachphaselast...
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遊離脂肪酸在高血壓伴代謝綜合徵的發病機制中的作用探討
...的能源物質之一。FFA又可分爲飽和脂肪酸(saturatedfattyacid,SFA)、單不飽和脂肪酸(monounsaturatedfattyacid,MuFA)和多不飽和脂肪酸(polyunsaturatedfattyacid,PuFA)。TangY[1]等的研究發現,磷酸二酯酶3B基因(phosphodiesterase3B,PDE3B)在脂肪組織表...
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Dietaryfatandplasmatotalhomocysteineconcentrationsin2adultagegroups:theHordalandHomocysteineStudy
...esandmeasurementofplasmatHcyconcentrations.Results:TheintakeofsaturatedFAs(SFAs)waspositivelyandsignificantly(Pfortrend0.001)associatedwithtHcyconcentrations;thedifferenceinplasmatHcyconcentrationsbetweenthehighestandlowestquartilesofSFAswas8.8%.Theintakeofmarinevery-long-chainn3FAswasinversel...
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TheAla54Thrpolymorphismofthefattyacidbindingprotein2geneisassociatedwithachangeininsulinsensitivityafterachangeinthetypeofdieta
...4wk.Thefirstdiet,whichallsubjectsconsumed,wasahighsaturatedfattyacid(SFA)diet(38%ofenergyasfatand20%ofenergyasSFAs).Thesecondandthirddietswereadministeredaccordingtoarandomizedcrossoverdesign,andtheyconsistedofalow-fatandhigh-carbohydratediet(CHOdiet;28%ofenergyfromfatand10%ofenergyfromSFAs)an...