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超聲莫非氏徵對診斷急性膽囊炎的臨牀價值
【摘要】目的本文旨在探討超聲莫非氏徵(SMS)在評價急性膽囊炎的臨牀價值。方法本組105例臨牀診斷急性膽囊炎患者經手術病理組織學證實爲急性膽囊炎33例、72例是由非急性膽囊炎引起的上腹部疼痛。結果SMS的總準確度是87%...
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RoleofmembranesphingomyelinandceramideinplatformformationforFas-mediatedapoptosis
...,astheresponsiblegeneshavenotbeenidentified.AftercloningageneresponsibleforSMsynthesis,SMS1,weestablishedSMsynthase–defectiveWR19LcellstransfectedwiththehumanFasgene(WR/Fas-SM(–)),andcellsthathavebeenfunctionallyrestoredbytransfectionwithSMS1(WR/Fas-SMS1).WeshowthatexpressionofmembraneSMenhances...
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奧曲肽對人卵巢癌細胞增殖影響的實驗研究
...的發生、發展以及防治具有重要的意義[2]。奧曲肽(SMS-201995,OCT)爲生長抑素8肽類似物,是第一個用於臨牀的生長抑素類似物,目前其主要用於肝癌、胃癌、胰腺癌的輔助治療。目前國內外關於奧曲肽對卵巢癌作用的研究報道較...
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短信平臺在無償獻血管理中的應用
...短信發送平臺,軟件將在計算機上建立短信發送默認站點SMSWEB。需使用短信發佈系統的工作站需在系統註冊表裏註冊動態鏈接庫文件iSMSClient2000.dll(在Windows“開始”菜單中運行“regsvr32D:\iSMSClient2000.dll”)[4]。 4.3程序的...
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中科院“愛因斯坦講席教授”JulianDavies訪問南海海洋所
...的視野與角度闡述了微生物產生的豐富小分子天然產物(SMs),在抗菌、抗腫瘤、抗病毒和其他疾病治療中所具有的應用潛力;指出SMs的存在在一定程度上是出於保護其生物體的繁殖優勢,但主要還是進行細胞間的信號傳遞。戴維...
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神經酰胺誘導的細胞凋亡在抗腫瘤研究中的應用
...sphingomyelinase,SMase),鞘磷脂合成酶(sphingomyelin-synthase,SMS)、糖苷神經酰胺合成酶(glucosylceramidesynthase,GCS)、神經酰胺合成酶(Cer-synthase)、神經酰胺激酶(CK)、神經酰胺水解酶(ceramidase)及絲氨酸棕櫚油酸轉移酶(serinepal...
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應用生長抑素類似物治療消化道類癌臨牀分析(附6例報告)
...ctonendocrinetherapyonalimen-tarycarcinoidwithSandostatinandsomatostatin(SMS).Methods6patientswithalimentarycarcinoidinourhospitalwereanalyzedretrospectivelyaccordingtodomesticandoverseasdocumentations.AllcasesweretreatedwithSando-statinandSMS.Thetumorswereresectedin5of6cases.ResultsTheclinicals...
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Cell:大型疾病信息新資源
...型中的基因,深入探討了這些疾病的潛在生物學。例如,SMS基因變異可引起一種稱作爲Snyder-Robinson綜合徵的罕見遺傳疾病。研究小組在小鼠體內關閉了同一基因,複製出了人類疾病中看到的結果。他們還發現了,在SMS突變人類中...
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RoleoftheBloodstreamImpactingForceandtheLocalPressureElevationintheRuptureofCerebralAneurysms
...ationattheaneurysmmayhavealargecontributiontothedevelopmentofcerebralaneurysms.Thegoalofthepresentstudyistoevaluatehowthebloodstreamimpactingforceandthelocalpressureelevationattheaneurysminfluencestheruptureofcerebralaneurysms.Methods—Atotalof29aneurysmswerecreatedin26patient-specificvesselmodels,...
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掌上醫院的建設:醫院患者服務的新途徑
...種應用2.1信息查詢患者可以方便地通過“掌上醫院”,以SMS(手機短信)、WAP、Internet(互聯網)查詢醫院介紹、醫生簡歷、專家排班、醫院物價(藥品費、耗材費、手術費、住院每日費用等)、檢查報告(檢驗、放射、B超、病...
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橋腦基底部梗死11例臨牀分析
...其中表現爲單純運動型輕偏癱(PMH)17例,感覺運動型卒中(SMS)3例,共濟失調輕偏癱(AH)4例,構音障礙手笨拙(DA-CH)6例,其他7例臨牀表現不典型。筆者通過對照提出,累及中下部橋腦基底旁正中部位的較大病竈可造成嚴重的肢體運動...
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IncidenceofRecurrentSubarachnoidHemorrhageAfterClippingforRupturedIntracranialAneurysms
...cht,TheNetherlands.AbstractBackgroundandPurpose—Becauseintracranialaneurysmsdevelopduringlife,patientswithsubarachnoidhemorrhage(SAH)andsuccessfullyoccludedaneurysmsareatriskforarecurrence.WestudiedtheincidenceofandriskfactorsforrecurrentSAHinpatientswhoregainedindependenceafterSAHandinwhomallaneu...
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腔隙性腦梗死診斷
...並動眼神經癱的交叉小腦共濟失調;(14)感覺運動性卒中(SMS,丘腦內囊綜合徵);(15)半身投擲動作;(16)基底動脈下部分支綜合徵;(17)延髓外側綜合徵;(18)橋延外側綜合徵;(19)記憶喪失綜合徵;(20)閉鎖綜合徵(雙側PMH);(21)其它...
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ReplytoALucas
...0{at}cornell.eduDearSir:WearepleasedthatLucasfoundthelistofpotentialmechanismsofmetabolicimprintinginourrecentreview(1)torepresentausefuladvancetoresearchers.However,wedonotagreewiththesuggestionthatthetermimprintingshouldberejected.Ourprincipalobjectiveinproposingaworkingdefinitionofmetabolicimprin...
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德國慕尼黑中醫教授與佛山中醫院試水合作培訓
...期一年的臨牀學習。返德後,他創建Hempen中醫診所,以及SMS醫生協會,對全歐洲的醫生進行中醫理論的教育推廣。2年前他受聘爲慕尼黑工業大學運動健康系教授,去年開設中醫專業課程,包括三年期的中醫理論課程。Hempen熱愛...
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Inthequesttostymietime,willlaboratorydatastandupinman?
...eedthatmultiple,seeminglystochasticprocessesdriveaging,theunderlyingmechanismsarevague.Therearesomanytheoriesonagingthatit’shardtokeeptrack.DidLeonardHayflickhitthenailofsenescenceontheheadwhenheproposedthatourcellscandividealimitednumberoftimes,afterwhichtheydie?Orischronicinflammationtheanswerto...
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NatureMethods:無需擴增的數字基因表達譜
...FatihOzsolak和哈佛醫學院的DavidTTing等擴展了單分子測序(SMS)技術,開發出少量數字基因表達譜(low-quantitydigitalgeneexpression,LQ-DGE)的應用。此成果發表在最新一期的《NatureMethods》上。利用LQ-DGE,Ozsolak等在無擴增步驟的情況下繪...
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Theendofthebeginning
...ularlywithingenes.InthecaseofF7,thereare48commonsingle-nucleotidepolymorphisms(SNPs)thatbehavestatisticallylike39independentvariantswithrespecttolinkagedisequilibrium(3).WhatthismeansfromapracticalstandpointisthatidentificationofthestateofoneoftheseSNPsdoesnotofferanyinformationaboutthestateoftheoth...
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Rai1duplicationcausesphysicalandbehavioralphenotypesinamousemodelofdup(17)(p11.2p11.2)
...ns,duplications,andinversionsarebeingrecognizedasimportantmutationalmechanismsinvolvedinseveralaspectsofgenomeevolution,susceptibilitytotraits,andhumangenomicdisorders(1–6).Althoughthesegmentalaneuploidyusuallyinvolvesseveralgenes,onlyasmallsubsetofthesegenesconveyphenotypesasafunctionofcopynumber...
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IdentificationofEmbolicStrokePatternsbyDiffusion-WeightedMRIinClinicallyDefinedLacunarStrokeSyndromes
...drome(DCHS),puremotorstroke(PMS),puresensorystroke(PSS),sensorimotorstroke(SMS),ataxichemiparesis(AH),homolateralataxia,andcruralparesis(HACP).2Theunderlyingmechanismisthoughttobelocalthrombosiscausedbymicroatheromaandlipohyalinosis.2–6Becauseoftheclearclinicaldefinitionoflacunarstrokesandthepresu...
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IntravenousAdministrationofAcetylsalicylicAcidDuringEndovascularTreatmentofCerebralAneurysmsReducestheRateofThromboembolicEvents
...endovascularcoilembolization.Methods—Twohundredandsixty-onecerebralaneurysmsweretreatedin247patientsbyendovascularcoilembolizationfromJanuary2001toSeptember2004.Additionalintravenousadministrationof250mgASAwasappliedsinceJanuary2003.Patientstreatedbefore(–ASA;n=102aneurysms)andafterthatdate(+ASA...
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生長抑素與腫瘤血管關係的研究
...、7肽、8肽和14肽等多個系列。具有代表性的有ovctreotide(SMS201-995,奧曲肽)、vapreotide(RC-160,伐普肽)、lanreotide(BIM23014,蘭瑞肽)及seglitide(MK-678,司格列肽)等。近年來,這些多肽較多地應用於腫瘤學研究中[4]。 1.2生長抑素受體(S...
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改變醫療保健產業的8家初創公司
...時獲取反饋和醫療支持(如通過語音支持系統IVR或短消息SMS)。(點評:ContextMedia公司,ShradhaAgarwal)作者:
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G-ProteineCcoupledReceptorPolymorphismsAreAssociatedwithAsthmainaLargeGermanPopulation
...bjective:Inalarge,nestedcase-controlstudy,associationsbetweenGPRApolymorphisms,asthma,andserumIgElevelswereanalyzed.Methods:Usingmatrix-assistedlaserdesorption/ionizationtime-of-flight(MALDI-TOF)technology,1,872Germanchildrenaged9to11years(including624childrenwithasthmaand/orbronchialhyperresponsive...
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Methylenetetrahydrofolatereductase:alinkbetweenfolateandriboflavin?
...fdailyrequirementsforthegeneralpopulation.Withtheidentificationofpolymorphisms,orcommonmutations,invitaminmetabolism,largepercentagesofthepopulationmayhavehigherrequirementsforspecificvitamins.Anadditionalcomplicationwithrespecttovitaminsinvolvedinhomocysteinemetabolismistheuncertaintyregardingthebe...
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善得定治療急性胰腺炎42例臨牀觀察
...tricacidsecretionintheZallinge-Ellisonsyadromebylongactionsoˉmatostatiu(SMS201-995).ScandJGastroenterol,1997,119:206. 3Tulassayz.KisfalvikPappM.Theeffectofthelong-actingsomatostatinaualogueocteolideoncaenileiu-iuoducedpancreacticsinrats.JGasˉtroeneral,1995,33(2):99. 4許...
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MolecularPhenotypesofAtherosclerosis
...einheritanceofmultiplegenevariantsasacollectionofsinglenucleotidepolymorphisms(SNPs)thatmaypredictboththesusceptibilitytoenvironmentalriskfactorsandthecharacteristicsoflesionprogression.However,thedevelopmentofmolecularsignaturesthatdefinelesionpredisposition,stageofprogression,treatmentindications,...
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Delayedprogressivevisuallossfollowingwrappingofbilateralclinoidalaneurysms:recoveryofvisionandimprovementinneuroimagingduringcorticosteroid
...inglue,orsomeothermaterialisanalternativetoclippinginsomeintracranialaneurysms1;thesurgeonmustbalancetheneedtocreatelocalinflammation(toreinforcethearterialwall)withtheriskthattheinflammationwillspreadanddamageadjacentstructures.Wrappingofclinoidalaneurysms,inparticular,rarelymayproducedelayedandsev...
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DifferentmodesofweightlossinAlzheimerdisease:aprospectivestudyof395patients
...tmentsofGerontology(OG,MM,RB,andPB)andGastroenterologyandClinicalNutrition(SMS),UniversityHospital,Nice,France,andtheDepartmentsofPublicHealth(SA)andInternalMedicineandClinicalGerontology(OGandBV),UniversityHospital,InstitutNationaldelaSanteetdelaRechercheMedicale(INSERM)U558,Toulouse,France2Support...
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Detection,Management,andProspectsfortheMedicalTreatmentofSmallAbdominalAorticAneurysms
...l@uhcw.nhs.ukSeriesEditor::RobertW.ThompsonATVBInFocusAbdominalAorticAneurysms:PathophysiologicalMechanismsandClinicalImplicationsAbstractSmallabdominalaorticaneurysms,upto5.5cmindiameter,areverycommon.Ultrasonographyisthemostcost-effectivemethodofdetectingtheseaneurysmsandkeepingthemundersurveillan...