InductionofTauPathologybyIntracerebralInfusionofAmyloid-??-ContainingBrainExtractandbyAmyloid-??DepositioninAPPxTauTransgenicMice
【摘要】Alzheimer??sdiseasepresentsmorphologicallywithsenileplaques,primarilymadeofextracellularamyloid-??(A??)deposits,andneurofibrillarylesions,whichconsistofintracellularaggregatesofhyperphosphorylatedtauprotein.Tostudytheinvivoinductionoftaupathology,dilutebrainextractsfromagedA??-depositing...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第12期Bvitamins,homocysteine,andneurocognitivefunctionintheelderly
...arlinskyH.Folate,vitaminB12andcognitiveimpairmentinpatientswithAlzheimer‘sdisease.ActaPsychiatrScand1992;86:3015.KristensenMO,GulmannNC,ChristensenJEJ,OstergaardK,RasmussenK.SerumcobalaminandmethylmalonicacidinAlzheimerdementia.ActaNeurolScand1993;87:47581.CrystalHA,OrtofE,FrishmanWH,G...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2000年71卷第2期EvolutionofCognitiveImpairmentAfterStrokeandRiskFactorsforDelayedProgression
...988;45:719–721.JobstKA,HindleyNJ,KingE,SmithAD.ThediagnosisofAlzheimer’sdisease:aquestionofimageJClinPsychiatry.1994;55(Suppl):22–31.MoscickiEK,LockeB,RaeDS.DepressivesymptomsamongMexicans:TheHispanicHealthandNutritionExaminationSurvey.AmJEpidemiol.1989;130:348–360.HughesCP,BergL,DanzingerWL...
醫源資料庫;在線期刊;中風學雜誌;2005年第36卷第12期人蔘皁苷Rg1對阿爾茨海默病模型大鼠學習記憶的影響
...病 基底神經節 喹啉酸 EffectofginsenosideRg1onAlzheimer‘sdiseaseofmodelrats LINaWANGLimin FunctionalLaboratory,BinzhouMedicalUniversity,Binzhou256603;DepartmentofAnatomy,BinzhouMedicalUniversity 【Abstract】ObjectiveToobservetheeffectofginsenosideRg1onratofAlz...
醫源資料庫;在線期刊;濱州醫學院學報;2007年第30卷第5期老年性癡呆症的病因與藥物治療現狀分析
...十分龐大的,老年人的多發病-老年癡呆症(AIzheimer’sdisease,AD)成爲困擾老年人身心健康的重要因素之一。因此,探討AD的病因和藥物治療已越來越成爲醫學界備受關注的問題。AD可分爲散發性AD(sporadicAD,SAD)和家族性AD(...
醫源資料庫;在線期刊;中華醫藥雜誌;2007年第7卷第5期Alzheimer病的T淋巴細胞功能活性檢測
...eimmune-associatedfunctionandactivityofTlymphocyteandseverityofAlzheimer′sdiseasestage.MethodsThepatientsweredividedintotwogroups-mildandmoderatelysevere-accordingtoseverityofdiseasestage,andtheirlymphocyteswerecompatedtothoseofelderlycontrols.MonoclonalantibodieslabeledbyFITCwereusedtolymphocytes...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學MAO-B抑制劑靛紅在神經科的研究進展
...in-hibitor,improvesbradykinesiaanddopaminelevelsinaratmodelofParkinson‘sdiseaseinducedbyJapaneseencephalitisvirus.JNeurolSci,2003,206(1):79-83. 20HomasT,MclendonC,ThomasG.L-deprenyl:nitricoxideproductionanddilationofcerebralbloodvessels.Neruoreport,1998,9(11):2595-2600....
資料庫;在線期刊;中華現代內科學雜誌;2005年第2卷第4期Homocysteine,Bvitamins,andcognitivedeficitintheelderly
...renotconductedinthegroupatgreatestrisk,thoseovertheageof70y.TheAlzheimer‘sDiseaseCo-operativeStudyisplanningamulticentertrialintheUnitedStatestoseewhetherBvitaminswillslowtheprogressionofdiseaseinpatientswithAlzheimerdisease.Alsoneededisatrialofhomocysteine-loweringvitaminsinthoseelderlywhohavedev...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2002年75卷第5期調心方有效部位對類AD大鼠大腦神經生長因子及其受體p75的影響
...abstractedfrom‘Heart-RegulatingFormula’intreatmentofratwithAlzheimer’sdisease(AD).MethodsTheratmodelofADwereinducedbyAβ25-35injectedintothebilateralamygdala.Toobservethespatiallearningandmemoryability,andbymeansofRT-PCRandimmunohistochemistryanalysismethods,inthebrainofthemodelanimal,th...
醫源資料庫;在線期刊;中華現代中西醫雜誌;2005年第3卷第18期CognitivedeclineandfattyacidcompositionoferythrocytemembranesTheEVAStudy
...BrJNutr2001;86:31321.BretelerMM.VascularriskfactorsforAlzheimersdisease:anepidemiologicperspective.NeurobiolAging2000;21:15360.SwanGE,DecarliC,MillerBL,etal.Associationofmidlifebloodpressuretolate-lifecognitivedeclineandbrainmorphology.Neurology1998;51:98693.GlynnRJ,BeckettLA...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2003年77卷第4期