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TheClinicalResearchForumandAssociationofAmericanPhysiciansdisagreewithcriticismoftheNIHRoadmap
...n.Therefore,wesuggestthatourcolleaguesconsidercarefullyhowtoconductthisdialogue.Thesediscussionsarenotrestrictedtothesciencecommunitybutmustinvolvethegovernment,themedia,patients,andthepublic.WemustredoubleourcollectiveeffortstoassisttheNIHdirectorindocumentingthereturnoninvestmentfrompubliclysuppor...
醫源資料庫；在線期刊；臨牀研究雜誌；2006年第116卷第8期 -
促性腺激素釋放激素激動劑對子宮肌瘤患者血紅蛋白及紅細胞壓積的影響
...卵泡期抽血，月經不規律者於應用GnRHa前一天抽血，兩者第二次抽血均於末次應用GnRHa４～６周後手術前一天進行。所有患者均於上午9時以前空腹抽取肘靜脈血。 1.2.4子宮體積測定於應用GnRHa前一天及手術前一天分別由專人經...
醫源資料庫；在線期刊；中華現代婦產科學雜誌；2005年第2卷第7期 -
肝硬化患者血清一氧化氮與低氧血癥關係的研究
...syndrome:clinicalobservationsandlackoftherapeuticresponsetosomatostatinanalogue.Chest，1993，104（2）:515-521.13MelotC，NaeijiR，DechampsP，etal.Pulmonaryandextrapulmonarycontributorstohypoxemiainlivercirrhosis.AmRevRaespirDis，1989，139（3）:632-640.14NunesH，LebrecD，MazmanianM，etal...
合作平臺；在線期刊；中華中西醫雜誌；2005年第6卷第5期；論著 -
Ghrelinresponsetocarbohydrate-enrichedbreakfastisrelatedtoinsulin
...iquid•appetite•hunger•satiety•satiation•visualanaloguescales•ghrelin•glucose•insulin•leptinINTRODUCTIONThegastricpeptideghrelin(1)appearstoplayapivotalroleintheregulationoffoodintake.Ghrelinconcentrationsinplasmarisegraduallybeforeamealanddecreaseimmediat...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2005年81卷第2期 -
Ghrelin對消化功能的影響
...腸動力Ghrelin是生長激素促分泌物質受體(growthhormonesecretagoguereceptor,GHS-R)的內源性配體,最早由Kojima等［1］從大鼠胃黏膜細胞分離、純化而得。Ghrelin不僅能有效促進生長激素(GH)分泌,還在攝食，促進胃酸分泌，促進胃動力，保護胃...
醫源資料庫；在線期刊；中華醫學實踐雜誌；2007年第6卷第8期 -
Mycobacteriumtuberculosisandthehostresponse
...nindependentstudies.CathepsinZ(expressedinearlyphagosomes),SP110(humanhomologueofIpr1;seebelow),theadaptorofToll-likereceptorsignalingMAL(TIRAP),andcomplementreceptor1(CR1,orCD35)(5)havebeenimplicatedinsinglestudies.AnOxford-Gambiacollaborationonagenome-wideassociationstudyhasbeenlaunchedtoenrolupto...
醫源資料庫；在線期刊；實驗醫學雜誌；2005年第201卷第11期 -
InhibitionofTriglycerideSynthesisasaTreatmentStrategyforObesity
...T2genewasidentifiedbypurifyingtheenzymefromafungus4andcloningmammalianhomologues.5DGATenzymescatalyzethefinalstepintheknownpathwaysoftriglyceridesynthesis(Figure1).Althoughthe2enzymesaredissimilarinproteinsequences,bothfacilitatethelinkageofasn-1,2-diacylglycerolwithafattyacylCoAtoformatriacylglycer...
醫源資料庫；在線期刊；動脈硬化血栓血管生物學雜誌；2005年第25卷第3期 -
Ghrelinactioninthebraincontrolsadipocytemetabolism
...tativeneuropeptideghrelin(10–18).Apartfromitsroleasagrowthhormonesecretagogue,exogenousghrelinadministrationcausesapositiveenergybalanceandincreasesbodyweightwhenadministeredpharmacologically(10,19,20).Aphysiologicalroleforendogenousghrelinissuggestedbythefactthatgeneticdeletionofghrelinoritsonlyk...
醫源資料庫；在線期刊；臨牀研究雜誌；2006年第116卷第7期 -
DevelopmentofColorimetricMicrotiterPlateAssayforAssessmentofAntimicrobialsagainstAcanthamoeba
...yphagawasfoundtobesignificantlylesssusceptibletoeachofthephosphocholineanalogues.Thenewlydescribedassayoffersanumberofadvantagesoverthosedescribedpreviously.Itislesslabor-intensivethanpreviouslydescribedassaysandissensitiveandrapid,andtheresultscanbereadinanonsubjectivemanner.Asitisbasedonastandard9...
醫源資料庫；在線期刊；微生物臨牀雜誌；2005年第43卷第2期 -
MechanismsUnderlyingCampylobacterfetusPathogenesisinHumans:Surface-LayerProteinVariationinRelapsingInfections
...ulence,undergohigh-frequencyphenotypicswitchingduetorecombinationofsaphomologues,resultinginantigenicvariation.ToinvestigatethemechanismsinvolvedinrelapsingC.fetusinfections,wecomparedSLPvariationin4pairsofC.fetusstrainsthatinfecthumans;initialandfollow-upisolationswereperformed20daysto34monthsapart...
醫源資料庫；在線期刊；傳染病學雜誌；2005年第191卷第12期