急性胰腺炎的發病與炎症細胞因子
...P模型中證實,AP發生後30分鐘腹腔內注射單劑PAF拮抗劑(BB-882,5mg/kg)可顯著降低血清澱粉酶並改善胰腺組織學評分。在BB-882Ⅱ期臨牀試驗中發現[25],BB-882亦能顯著減輕AP患者的血清IL-6、IL-8水平,降低器官衰竭的發病率,改變AP...
合作平臺;醫學論文;基礎醫學論文;生物化學PigmentEpithelium-DerivedFactorInhibitsNeointimalHyperplasiaafterVascularInjurybyBlockingNADPHOxidase-MediatedReactiveOxygenSpeciesGeneration
...njurythroughitsantioxidativeproperties.BiochemBiophysResCommun2002,296:877-882YamagishiS,InagakiY,OkamotoT,AmanoS,KogaK,TakeuchiM,MakitaZ:Advancedglycationendproducts-inducedapoptosisandoverexpressionofvascularendothelialgrowthfactorandmonocytechemoattractantprotein-1inhumanculturedmesangialcells.JB...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第6期MinimalDurationofOralMatrixMetalloproteinaseInhibitiontoPreventConstrictiveArterialRemodelingafterBalloonDilationinthePig
...ectsonneointimalhyperplasiaandvascularremodeling.JAmCollCardiol1999;33:876-882.BosmansJM,VrintsCJ,KockxMM,BultH,CromheekeKMC,HermanHG.ContinuousperivascularL-argininedeliveryincreasestotalvesselareaandreducesneointimalthickeningafterexperimentalballoondilatation.ArteriosclThrombVascBiol1999;19:767-7...
醫源資料庫;在線期刊;中風學雜誌;2001年第1卷第2期MinimalDurationofOralMatrixMetalloproteinaseInhibitiontoPreventConstrictiveArterialRemodelingafterBalloonDilationinthePig1
...ectsonneointimalhyperplasiaandvascularremodeling.JAmCollCardiol1999;33:876-882.BosmansJM,VrintsCJ,KockxMM,BultH,CromheekeKMC,HermanHG.ContinuousperivascularL-argininedeliveryincreasestotalvesselareaandreducesneointimalthickeningafterexperimentalballoondilatation.ArteriosclThrombVascBiol1999;19:767-7...
醫源資料庫;在線期刊;放射學雜誌;2003年1月第226卷第2期Cytokine-induceddifferentiationofmultipotentadultprogenitorcellsintofunctionalsmoothmusclecells
...fneointimaformationandremodelingintheporcinecoronaryartery.Circulation.103:882–888.JainM.K.,etal.1996.MolecularcloningandcharacterizationofSmLIM,adevelopmentallyregulatedLIMproteinpreferentiallyexpressedinaorticsmoothmusclecells.J.Biol.Chem.271:10194–10199.KumarM.S.andOwensG.K.2003.Combinatorial...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第12期AlteredPDGF-BB–Inducedp38MAPKinaseActivationinDiabeticVascularSmoothMuscleCells
...38mitogen-activatedproteinkinase(MAPK)byplatelet-derivedgrowthfactor(PDGF)-BBanditsbiologicaleffectsinculturednormalanddiabeticratvascularsmoothmusclecells(VSMCs).MethodsandResults—VSMCgrowthfromdiabeticratswasfasterthanthatfromnormalrats.TheexpressionofthePDGF?-receptorindiabeticVSMCswassignifica...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第11期新生兒缺氧缺血性腦病臍血肌酸激酶腦型同工酶和神經元特異性烯醇化酶變化及臨牀意義
...血性腦病的新生兒爲病例組,生後立即收集臍血,檢測CK-BB及NSE值。結果新生兒HIE組臍血CK-BB及NSE水平明顯高於對照組,差異有非常顯著性(P<0.01),且與HIE程度呈正相關。結論新生兒缺氧缺血性腦病組臍血CK-BB及NSE水平高於對照...
醫源資料庫;在線期刊;中華現代兒科學雜誌;2007年第4卷第1期妥泰治療癲癇前後血清中S-100、CK-BB變化意義的研究
...P)治療前後患兒血漿S-100蛋白,肌酸激酶腦型同工酶(CK-BB)的測定,揭示妥泰對全身發作性癲癇患兒的腦保護作用。方法採用雙抗體夾心測定血清中S-100、CK-BB,採用NAC法測定。結果全身發作性癲癇患兒妥泰治療後3個月S-100、CK-...
醫源資料庫;在線期刊;中華現代兒科學雜誌;2006年第3卷第1期淋巴細胞激活誘導的受體4-1BB在類風溼關節炎T淋巴細胞亞羣上的表達
...類風溼關節炎(RA)T淋巴細胞上淋巴細胞激活誘導的受體4-1BB的表達及其作用機制。研究者應用流式細胞術檢測30例RA患者和20名正常對照者外周血T細胞活化前後4-1BB的表達。結果RA患者CD4+T和CD8+T細胞表達的4-1BB明顯高於正常對照組[...
行業資訊;臨牀快報;免疫系統SuppressionofActivationofSignalTransducerandActivatorofTranscription-BSignalingintheVesselWallReducesBalloonInjury-InducedNeointimaFormatio
...esselwallremodeling,weexamineditsinvolvementinplatelet-derivedgrowthfactor-BB(PDGF-BB)-stimulatedVSMCgrowthandmotilityandballooninjury-inducedneointimaformation.PDGF-BBactivatedSTAT-5Basmeasuredbyitstyrosinephosphorylation,DNAbinding,andreportergeneactivity.PDGF-BBinducedcyclinD1expression,CDK4activ...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第10期