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Interleukin12p40isrequiredfordendriticcellmigrationandTcellprimingafterMycobacteriumtuberculosisinfection
1TrudeauInstitute,Inc.,SaranacLake,NY129832GenentechInc.,SouthSanFrancisco,CA94080Migrationofdendriticcells(DCs)tothedraininglymphnode(DLN)isrequiredfortheactivationofnaiveTcells.WeshowherethatmigrationofDCsfromthelungtotheDLNafterMycobacteriumtuberculosis(Mtb)exposureisdefectiveinmicelackinginterle...
醫源資料庫；在線期刊；實驗醫學雜誌；2006年第203卷第7期 -
PlasmavitaminB-12concentrationsrelatetointakesourceintheFraminghamOffspringStudy
...ton,MA02111.E-mail:tucker{at}hnrc.tufts.edu.ABSTRACTBackground:LowvitaminB-12statusisprevalentamongtheelderly,butfewstudieshaveexaminedtheassociationbetweenvitaminB-12statusandintake.Objective:WehypothesizedthatvitaminB-12concentrationsvaryaccordingtointakesource.Design:Plasmaconcentrationsanddietar...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2000年71卷第2期 -
白細胞介素-12與支氣管哮喘研究進展
【摘要】白細胞介素-12（IL-12）是一種具有廣泛生物學活性的細胞因子，主要由激活的炎性細胞產生。IL-12具有調節Th1/Th2細胞免疫應答的作用，這種細胞因子的減少或缺失導致Th2細胞的優勢分化，誘發哮喘發生。因此深入研究IL-1...
合作平臺；在線期刊；中華醫學研究雜誌；2005年第5卷第6期；綜述 -
婦科名老中醫朱南孫的醫案
...足，衝任統攝乏力。治宜健脾益腎，調理衝任。焦潞黨蔘12g焦白朮9g炒淮山藥12g補骨脂9g椿根皮12g煨肉果12g桑寄生12g桑螵蛸、海螵蛸(各)12g芡實須、蓮子須(各)9g玉米鬚2g焦山楂炭12g7帖二診：9月9日。經行9天方淨，經量初少後爲中...
求醫問藥；專家門診；名家醫案 -
ScreeningforvitaminB-12andfolatedeficiencyinolderpersons
...dKingdom.E-mail:robert.clarke{at}ctsu.ox.ac.uk.ABSTRACTBackground:VitaminB-12deficiencyisusuallyaccompaniedbyelevatedconcentrationsofserumtotalhomocysteine(tHcy)andmethylmalonicacid(MMA).FolatedeficiencyalsoresultsinelevatedtHcy.MeasurementofthesemetabolitescanbeusedtoscreenforfunctionalvitaminB-12o...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2003年77卷第5期 -
Adailyintakeofapproximately6µgvitaminB-12appearstosaturateallthevitaminB-12–relatedvariablesinDanishpostmenopausalwomen
...kurbor{at}hotmail.com.ABSTRACTBackground:RecommendeddailyintakesofvitaminB-12varybetween2and6µg.Objective:TheobjectivewastoexaminetheassociationsbetweenvitaminB-12intakeandmarkersofvitaminB-12deficiency.Design:Westudied98Danishpostmenopausalwomenaged41–75y.Serumcobalamin,transcobalamin(TC)...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2006年83卷第1期 -
VitaminB-12metabolisminHIV-infectedpatientsintheageofhighlyactiveantiretroviraltherapy:roleofhomocysteineinassessingvitaminB-12status
...antiretroviraltherapy(HAART),20%and10%ofHIV-infectedpatientshadlowvitaminB-12andredbloodcellfolate(RBCF)concentrations,respectively.However,fewpatientshadrealvitaminB-12deficiency.Objective:WeevaluatedtheprevalenceoflowvitaminB-12andRBCFconcentrationsinHIV-infectedpatientsreceivingHAARTandtheusefuln...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2003年77卷第2期 -
Ala12variantoftheperoxisomeproliferator-activatedreceptor-gene(PPARG)isassociatedwithhigherpolyunsaturatedfatinadiposetissueandattenuatest
...disease.Lessisknownaboutthegeneticvariationmodulatingthisassociation.TheAla12alleleoftheperoxisomeproliferator-activatedreceptor-gene(PPARG)decreasesthelipolysisoftriacylglycerolsinadiposetissue,whichresultsintheaccumulationoffattyacidsinadipocytes.Objective:WeaimedtodeterminewhetherthePro12Alapolym...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2007年86卷第4期 -
DomainsNecessaryforG12BindingandStimulationofProteinPhosphatase-2A(PP2A):IsG12aNovelRegulatorySubunitofPP2A?
...),awidelyexpressedserine/threoninephosphatase,andtheheterotrimericGproteinG12.PP2Aactivityisalteredincarcinogenesisandinsomeneurodegenerativediseases.WehaveidentifiedbindingofG12withtheAsubunitofPP2A,atrimericenzymecomposedofA(scaffolding),B(regulatory),andC(catalytic)subunitsanddemonstratedthatG12s...
醫源資料庫；在線期刊；分子藥理學雜誌；2007年第69卷第5期 -
VegetarianismandvitaminB-12(cobalamin)deficiency
...2),whosesustainedinvestigationsofclinicallyrelevantissuesrelatedtovitaminB-12,folate,andone-carbonmetabolismearnedhimrespect,admiration,andstatusasoneofthegiantsinthisfield.(Internet:http://www.victorherbert.com,accessed4March2003.)3SupportedbyNIHgrantsR01CA58919andR01HD39295andbyaVeteransAffairsMer...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2003年78卷第1期