Thecharacterisationofhyalocytes:theorigin,phenotype,andturnover
...ransmissionandscanningelectronmicroscopywasperformedinrateyes.Immunophenotypicalanalysiswasperformedbyeitheranti-ED1orED2antibodies.Toexaminetheoriginofthehyalocytes,thechimericmicewerecreatedandwereusedtotransplantthebonemarrow(BM)cellsfromenhancedgreenfluorescentprotein(EGFP)transgenicmice.Theturn...
醫源資料庫;在線期刊;英國眼科學雜誌;2005年第89卷第4期氨基酸分子的模糊聚類分析
【摘要】本文選用氨基酸分子的相對分子量、pI值、疏水性值以及保守性值這四個參數,利用模糊聚類的方法,對20種氨基酸分子進行了分類。通過對分類結果的分析,有助於我們研究蛋白質的相似性問題。【關鍵詞】氨基酸;...
醫源資料庫;在線期刊;中華醫學研究雜誌;2006年第6卷第2期醫學微生物學-放線菌與諾卡菌、螺旋體、支原體、立克次體、衣原體複習題
...的症狀和體徵應包括A.皮疹B.中毒性休克、DICC.高熱D.劇烈頭痛30.恙蟲病的臨牀體徵有A.焦痂B.劇烈頭痛C.可出現耳聾D.高熱31.沙眼衣原體可引起下列哪些疾病A.沙眼B.包含體結膜炎C.泌尿生殖道感染D.性病淋巴肉芽腫E.衣原體肺炎32....
醫源資料庫;醫源習題集;醫學微生物學C-PeptideColocalizeswithMacrophagesinEarlyArterioscleroticLesionsofDiabeticSubjectsandInducesMonocyteChemotaxisInVitro
...Medicine(P.L.),LeducqCenterforCardiovascularResearch,BrighamandWomen’sHospitalandHarvardMedicalSchool,Boston,MA;andtheHealthSciencesCenter(A.Z.,S.H.,J.S.),LouisianaStateUniversity,NewOrleans,LA.CorrespondencetoNikolausMarx,MD,DepartmentofInternalMedicineII–Cardiology,UniversityofUlm,Robert-Koch-...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第3期血管性頭痛患者87例的經顱多普勒與腦電圖對比分析
...目的探討經顱多普勒(TCD)與腦電圖(EEG)在診斷血管性頭痛中的作用。方法對87例血管性頭痛患者同時做TCD與EEG檢測,分別觀察其相應變化,對比分析其結果。結果血管性頭痛患者TCD檢測異常率高(92.0%),EEG異常率低(12.6%)...
醫源資料庫;在線期刊;中華現代影像學雜誌;2005年第2卷第11期RepressionofSPI2transcriptionbynitricoxide-producing,IFN-activatedmacrophagespromotesmaturationofSalmonellaphagosomes
...,thetypeIIIsecretionsystemencodedwithintheSalmonellapathogenicityisland-2(SPI2)helpsSalmonellathrivewithinprofessionalphagocytes.Wereportherethatnitricoxide(NO)generatedbyIFN-activatedmacrophagesabrogatestheintracellularsurvivaladvantageassociatedwithafunctionalSPI2typeIIIsecretionsystem.NOcongeners...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第5期RegulationofanaphylacticresponsesbyphosphatidylinositolphosphatekinasetypeI
...harmacology,StateUniversityofNewYork,StonyBrook,NY11794Themembranephospholipidphosphatidylinositol4,5-bisphosphate[PI(4,5)P2]isacriticalsignaltransducerineukaryoticcells.However,thephysiologicalrolesofthetypeIphosphatidylinositolphosphatekinases(PIPKIs)thatsynthesizePI(4,5)P2arelargelyunknown.Here,w...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第6期Hyperactivationofp21rasandPI3Kcooperatetoaltermurineandhumanneurofibromatosistype1–haploinsufficientosteoclastfunctions
...iththatinsyngeneicWTmice.IntercrossingNf1+/–miceandmicedeficientinclass1API3K(p85)restoredelevatedPI3KactivityandNf1+/–osteoclastfunctionstoWTlevels.Furthermore,invitro–differentiatedosteoclastsfromNF1patientsalsodisplayedelevatedRas/PI3Kactivityandincreasedlyticactivityanalogoustothoseinmurin...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第11期FarnesoidXreceptorisessentialfornormalglucosehomeostasis
...acidreceptorfarnesoidXreceptor(FXR;NR1H4)isacentralregulatorofbileacidandlipidmetabolism.WeshowherethatFXRplaysakeyregulatoryroleinglucosehomeostasis.FXR-nullmicedevelopedseverefattyliverandelevatedcirculatingFFAs,whichwasassociatedwithelevatedserumglucoseandimpairedglucoseandinsulintolerance.Theiri...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第4期CilostazolProtectsAgainstBrainWhiteMatterDamageandCognitiveImpairmentinaRatModelofChronicCerebralHypoperfusion
...dimmunohistochemistryfor4-hydroxy-2-nonenal(HNE),glutathione-S-transferase-pi(GST-pi),ionizedcalcium-bindingadaptormolecule1,phosphorylatedCREB(p-CREB),Bcl-2,andcyclooxygenase-2(COX-2)wereanalyzedatbaselineandat3,7,14,21,and28daysafterhypoperfusion.Result—Cilostazolsignificantlyimprovedspatiallear...
醫源資料庫;在線期刊;中風學雜誌;2006年第37卷第6期