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LeukotrieneB4,anactivationproductofmastcells,isachemoattractantfortheirprogenitors
...omedicalSciencesDivision,FacultyofMedicine,ImperialCollegeLondon,SouthKensington,LondonSW72AZ,England,UK2DepartmentofVeterinaryClinicalStudies,UniversityofEdinburgh,EasterBushVeterinaryCentre,Roslin,Midlothian,EH259RG,Scotland,UKMastcellsaretissue-residentcellswithimportantfunctionsinallergyandinfla...
醫源資料庫；在線期刊；實驗醫學雜誌；2005年第201卷第12期 -
反相高效液相色譜法同時測定鎘、鉛、銅和鋅
...合物和試劑在15min內出峯完畢。4種離子的檢出限爲:Cd2+0.02ng,Pb2+0.02ng,Cu2+0.02ng,Zn2+0.12ng；線性範圍爲:Cd2+0.8μg/L～150μg/L,Pb2+0.8μg/L～300μg/L,Cu2+0.8μg/L～500μg/L,Zn2+5.0μg/L～1000μg/L；方法的日內相對標準偏差爲:2.8%～4.8%，測定低、中、高...
藥品天地；專業藥學；實驗技術；色譜技術；色譜分析實例 -
國產與進口苯磺酸氨氯地平片的人體生物等效性研究
...氯地平片的AUC0-144分別爲（378.8±73.36）、（385.5±83.62）（ng·h）/ml；AUC0-∞分別爲（414.8±72.03）、（415.2±82.1）（ng·h）/ml；Cmax分別爲（8.26±1.48）、（8.25±1.91）ng/ml；tmax分別爲（7.40±0.94）、（7.60±0.75）h；t1/2分別爲（39.64±8.31）...
醫源資料庫；在線期刊；中華實用醫藥雜誌；2007年第7卷第9期 -
Real-TimePCRAssayToDetectSmallpoxVirus
...rplatforms.TheassayisbasedonTaqManchemistrywiththeorthopoxvirushemagglutiningeneusedasthetargetsequence.WithgenomicDNApurifiedfromvariolavirusBangladesh1975,thelimitofdetectionwasestimatedtobeapproximately25copiesonbothmachines.Theassaywasevaluatedinablindedstudywith322codedsamplesthatincludedgenomi...
醫源資料庫；在線期刊；微生物臨牀雜誌；2003年第41卷第8期 -
AmultipotentprecursorinthethymusmapstothebranchingpointoftheTversusBlineagedecision
...theclonaldifferentiationpotentialofthemostimmatureprecursorsinthethymus.UsingaCCchemokinereceptor9–enhancedgreenfluorescentproteinknock-inallelelikeasurfacemarkerofunknownfunction,weidentifyamultipotentprecursorpresentinbonemarrow,blood,andthymus.SinglecellsofthisprecursorgiverisetoT,B,anddendriti...
醫源資料庫；在線期刊；實驗醫學雜誌；2005年第202卷第1期 -
InductionofAPOBEC3familyproteins,adefensivemaneuverunderlyinginterferon-inducedanti–HIV-1activity
...search,NationalInstitutesofHealth,Bethesda,MD20892ApolipoproteinBmRNA-editingenzyme-catalyticpolypeptide-like3G(APOBEC3G),acytidinedeaminase,isarecentlyrecognizedinnateintracellularproteinwithlethalactivityagainsthumanimmunodeficiencyvirus(HIV).Packagedintoprogenyvirions,APOBEC3Genzymaticactivitylea...
醫源資料庫；在線期刊；實驗醫學雜誌；2006年第203卷第1期 -
Lossoftheproapoptoticprotein,Bim,breaksBcellanergy
...poptoticprotein,Bim,controlsthefateofanergicBcells.Totestthisidea,micelackingBimwerecrossedwithmicethatexpresssolublehenegglysozymeandwhoseBcellsbearreceptorsspecificfortheprotein.InBim+/+micetheseBcellsareanergicanddierapidly.IfthemicelackBim,however,theBcellslivelonger,aremoremature,respondtoantig...
醫源資料庫；在線期刊；實驗醫學雜誌；2006年第203卷第3期 -
UseofaSuspensionArrayforRapidIdentificationoftheVarietiesandGenotypesoftheCryptococcusneoformansSpeciesComplex
...tyofMiami,Miami,Florida3314ABSTRACTCryptococcusneoformansisanencapsulatedfungalpathogenknowntocauseseverediseaseinimmunocompromisedpatients.Thedisease,cryptococcosis,ismostlyacquiredbyinhalationandcanresultinachronicmeningoencephalitis,whichcanbefatal.Here,wedescribeamolecularmethodtoidentifythevari...
醫源資料庫；在線期刊；微生物臨牀雜誌；2005年第43卷第8期 -
11-HSD1inhibitionamelioratesmetabolicsyndromeandpreventsprogressionofatherosclerosisinmice
...se(HSD)type1convertsinactivecortisoneintoactivecortisolincells,therebyraisingtheeffectiveglucocorticoid(GC)toneaboveserumlevels.Wereportthatpharmacologicinhibitionof11-HSD1hasatherapeuticeffectinmousemodelsofmetabolicsyndrome.Administrationofaselective,potent11-HSD1inhibitorloweredbodyweight,insulin...
醫源資料庫；在線期刊；實驗醫學雜誌；2005年第202卷第4期 -
G-CSF–stimulatedNeutrophilsAreaProminentSourceofFunctionalBLyS
...ofClinicalandExperimentalMedicine,UniversityofVerona,37134Verona,Italy3HumanGenomeSciences,Inc.,Rockville,MD208504DepartmentofExperimentalMedicine,UniversityofPadova,35121Padova,Italy AbstractTopAbstractIntroductionMaterialsandMethodsResultsandDiscussionReferencesBlymphocytestimulator(BLyS)isanove...
醫源資料庫；在線期刊；美國病理學雜誌；2003年第162卷第3期