Asp92AsnPolymorphismintheMyeloidIgAFcReceptorIsAssociatedWithMyocardialInfarctioninTwoDisparatePopulations
...tmediateprogressionofatherosclerosis,includinggenesinvolvedinthrombosis,plaqueinstability,andinflammation.3Manyoftheinflammatoryprocessesthatoccurduringatherosclerosisinvolvemonocytesandmacrophages.4Theactivationofthesecellscanberegulatedbycellsurfacereceptorsforimmunoglobulin,suchasthemyeloidIgAFcr...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第12期大陸地區引用次數最高的生物類論文
...引次數最多的20篇文章:TheERA-40re-analysis(Cited624time(s))2005;QuarterlyJournaloftheRoyalMeteorologicalSociety;Uppala,S.M.,Karing;llberg,P.W.,Simmons,A.J.,Andrae,U.,daCostaBechtold,V.,...Effectsofradiotherapyandofdifferencesintheextentofsurgeryforearlybreastcanceronlocalrecurrenceand15-ye...
醫學教育;科教新聞不穩定型心絞痛病人β-血小板球蛋白濃度的檢測
...織因子和膠原物質相接觸而引發血小板活化。活化導致α顆粒膜與質膜融合,使血小板內部的顆粒成分被釋放,其中包括血小板基蛋白(PBP)及其衍生物,如血小板因子4(PF4)、β-TG等[2]。位於血小板α顆粒膜上的GMP-140只在活...
醫源資料庫;在線期刊;齊魯醫學雜誌;2006年第21卷第6期MultilocusSequenceTypingLackstheDiscriminatoryAbilityofPulsed-FieldGelElectrophoresisforTypingSalmonellaentericaSerovarTyphimurium
...eldgelelectrophoresis(PFGE)iscurrentlyconsideredthe“goldstandard“techniqueintypingSalmonella.TheaimofthisstudywastocomparethediscriminatorypowerofPFGEtomultilocussequencetyping(MLST)intypingSalmonellaentericaserovarTyphimuriumclinicalisolates.Atotalof85SalmonellaTyphimuriumclinicalisolatesfromca...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第5期Identificationofthetargetself-antigensinreperfusioninjury
...aratmodelofmyocardialinfarctionsuggestedaroleforinnateimmunityinRI(9).Subsequently,Weismanetal.demonstratedthatpretreatmentofratswithaspecificsolubleinhibitorofcomplementC3(sCR1)dramaticallyreducedinjuryinasimilarmodelofmyocardialinfarctionandfurtherestablishedtheimportanceofcomplementasamediatorofi...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第1期cIAP2isaubiquitinproteinligaseforBCL10andisdysregulatedinmucosa-associatedlymphoidtissuelymphomas
...mediatedNF-Bactivation,theroleofcIAP2isnotclear.HereweshowthatcIAP2isaubiquitinligase(E3)ofBCL10andtargetsitfordegradation,inhibitingantigenreceptor–mediatedcytokineproduction.cIAP2-MALT1lacksE3activity,andconcomitantly,theBCL10proteinisstabilizedinMALTlymphomasharboringthisfusion.Furthermore,BCL1...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第1期護理工作質量管理系統的探析
...相互補充和制約,故護理工作質量總影響E=Ⅰ·Ⅱ。假設Q是護理工作質量的最理想值(在現有的技術條件下達到的預期目標),受影響因素形成的偏差假設爲ε,則有下式:ε=(Q-E)=ε1ε2=[Q1-Ⅰ][Q2-Ⅱ] 其中,Q1、Q2分別是...
資料庫;在線期刊;中華現代醫院管理雜誌;2004年第2卷第10期YersiniavirulencefactorYopJactsasadeubiquitinasetoinhibitNF-Bactivation
...daidinestablishingasystemicinfection.Here,weshowthatYopJisapromiscuousdeubiquitinatingenzymethatnegativelyregulatessignalingbyremovingubiquitinmoietiesfromcriticalproteins,suchasTRAF2,TRAF6,andIB.IncontrasttothecylindromatosistumorsuppressorCYLD,whichattenuatesNF-BsignalingbyselectivelyremovingK63-l...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第10期HighFrequencyofGastricColonizationwithMultipleHelicobacterpyloriStrainsinVenezuelanSubjects
...idualhost.Usingenzyme-linkedimmunosorbentassayandlineprobeassay(LiPA)techniques,weanalyzedtheprevalenceofmixedH.pyloricolonizationin127subjectsfromVenezuela,acountryofhighH.pyloriprevalence,fromthreeregionsrepresentingdifferentpopulationgroups:theAndes(Merida),whereCaucasianmestizospredominate,amajo...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第6期Neutrophilsfromp40phox–/–miceexhibitseveredefectsinNADPHoxidaseregulationandoxidant-dependentbacterialkilling
...itide3-kinase;ROS,reactiveoxygenspecies.C.D.EllsonandK.Davidsoncontributedequallytothiswork.Thereducednicotinamideadeninedinucleotidephosphate(NADPH)oxidaseofneutrophilsandmacrophagesplaysanessentialroleinthemechanismsbywhichthesecellsdestroyengulfedpathogens(1,2).Thedeliveryofsuperoxideanion(O2–)...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第8期