Impactofgeneticbackgroundonnephropathyindiabeticmice
...tytorenalpathologicalchanges,therewasasignificantpositivecorrelationbetweenbloodglucoseandthedegreeofmesangialexpansion,suggestingthatmostofthevariabilityinrenalpathologicalabnormalitieswasbecauseofdifferencesinhyperglycemia.Althoughthegeneralcharacterofrenalinvolvementwassimilarbetweenchemicalandge...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第1期HypercholesterolemiaReducesCollateralArteryGrowthMoreDominantlyThanHyperglycemiaorInsulinResistanceinMice
...epathogenesisofinsulinresistanceandtype2diabetes.13-18Furthermore,considerableattentionhasbeendrawntotheglycationand/oroxidationoflipoproteinsasareasonforacceleratedatherosclerosisintype1diabeticpatients.19,20Inthepresentstudy,wewishedtocomparetheeffectsofeitherdisturbedglucosemetabolismordisturbedl...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第6期第四節 近交品系的命名法--一、近交系的命名法
...在大寫英文字母間加入一些阿拉拍數字來表示,如C3H、C57BL、C57BR、C57L、CC57W、CC57BR等。 3.非正規的命名,如果已廣泛爲國際所共知者,則可保留沿用,如:“129”、“101”、“615”等。 4.近交代數表示,一般是在品系...
醫源資料庫;醫源圖書館;教材類;醫用實驗動物學Antigentargetingtodendriticcellselicitslong-livedTcellhelpforantibodyresponses
...esanddendriticcellsasaccessorycellsforTcellreplication.J.Exp.Med.158:174–191.Inaba,K.,andR.M.Steinman.1985.Protein-specifichelperT-lymphocyteformationinitiatedbydendriticcells.Science.229:475–479.Banchereau,J.,andA.K.Palucka.2005.Dendriticcellsastherapeuticvaccinesagainstcancer.Nat.Rev.Immunol.5...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第3期PathogenicRoleofBCellsinAnti-CD0-InducedNecroinflammatoryLiverDisease
...leteCD4+andCD8+Tcells,micewereinjectedintravenouslywithratanti-mouseCD4(YTS191.1)andratanti-mouseCD8(YTS169.4)mAb,22bothkindlyprovidedbyDr.R.Zinkernagel(UniversityofZurich,Zurich,Switzerland).TodepleteNKcellsintheliver,micewereinjectedintravenouslywithrabbitanti-mouseasialo-GM1antibody(50µg/mo...
醫源資料庫;在線期刊;美國病理學雜誌;2006年第168卷第3期TumorcellsconvertimmaturemyeloiddendriticcellsintoTGF-–secretingcellsinducingCD4+CD25+regulatoryTcellproliferation
...ell–specificdominantnegativetransforminggrowthfactorIIreceptor.J.Exp.Med.191:1187–1199.作者:FranoisGhiringhelli,PierreE.Puig,StephanRoux
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第7期IncreasedexpressionofvascularendothelialgrowthfactorassociatedwithaccumulationoflipidsinBruch’smembraneofLDLreceptorknockoutmice
...tylipoprotein(LDL)receptordeficiency.Methods:LDLreceptordeficientmiceandC57BL/6controlswerefedastandarddietorahighfat(HF)diet.Plasmatotalcholesterol(pTC)wasdetermined.Eyeswereexaminedbytransmissionelectronmicroscopy.ImmunohistochemicalstainingforVEGFwasperformed.Results:pTCwerehighestinLDLreceptorde...
醫源資料庫;在線期刊;英國眼科學雜誌;2005年第89卷第12期InducibleNitricOxideSynthaseContributestoVentilator-inducedLungInjury
...opkinsUniversitySchoolofMedicine,Baltimore,MarylandABSTRACTRationale:Induciblenitricoxidesynthase(iNOS)hasbeenimplicatedinthedevelopmentofacutelunginjury.RecentstudiesindicatearoleformechanicalstressiniNOSandendothelialNOS(eNOS)regulation.Objectives:ThisstudyinvestigatedchangesinlungNOSexpressionand...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第8期Mastcellscanpromotethedevelopmentofmultiplefeaturesofchronicasthmainmice
...mationincludinginfiltrationwitheosinophilsandlymphocytes,airwayepithelialgobletcellhyperplasia,enhancedexpressionofthemucingenesMuc5acandMuc5b,andincreasedlevelsoflungcollagen.Usingmastcell–deficient(KitW-sh/W-shand/orKitW/W-v)miceengraftedwithFcR+/+orFcR–/–mastcells,wefoundthatmastcellswerere...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第6期七、國際上常用的F1動物
...、國際上常用的F1動物 1.AKD2F1AKR×DBA/2 2.BA2CF1C57BL×A2G 3.BCF1C57BL×BALB/C 4.BCBAF1C57BL×CBA 5.BC3F1C57BL×C3H 6.B6AF1C57BL×6×A 7.B6D1F1C57BL/6×DBA/1 8.CAF1BALB/C×A 9.CAKF1BALB/C×AKR 10.CBA-T6D2F1CBA-T6×DBA/2...
醫源資料庫;醫源圖書館;教材類;醫用實驗動物學