PathogenicRoleofBCellsinAnti-CD0-InducedNecroinflammatoryLiverDisease
...nisticanti-CD40monoclonalantibody(CD40)causesabiphasicinflammatoryliverdiseaseininbredmice.ThelatephaseofdiseasewassuppressedinB-cell-deficientmiceandbythedepletionofmacrophages,butnotTcellsornaturalkillercells.WealsoreportthatSCIDmicewerenotsusceptibletoCD40-inducedliverdiseaseunlesstheywerereconst...
醫源資料庫;在線期刊;美國病理學雜誌;2006年第168卷第3期第二軍醫大學發表癌症表觀遺傳學研究
...GAD1受到H3K27me3的沉默,DNA甲基化敏感的CTCF結合位點(CTCF-BS3)是GAD1被重新激活的關鍵位點。染色體構象捕獲(3C)分析表明,正常細胞的CTCF二聚化(CTCF結合未甲基化的CTCF-BS3和CTCF-BS2)在染色體內部形成了一個環。這種CTCF二聚...
行業資訊;臨牀快報;腫瘤相關DownButNotOut
...ousanimalmodelsincludingbaboons,rats,rabbits,mice,andpigs.4v?3expressionisobservedrapidlyinthemediaafterinjuryandisfoundintheneointimawithin7days,withpeaklevelsat14to28days.2–7v?3integrinexpressioncolocalizeswith-actinintheinjuredarteries,suggestingthatSMCswithinthevesselwallexpressv?3integrinsaft...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2005年第25卷第7期AlbuminTreatmentReducesNeurologicalDeficitandProtectsBlood–BrainBarrierIntegrityAfterAcuteIntracorticalHematomaintheRat
theCerebralVascularDiseaseResearchCenter,DepartmentofNeurology,UniversityofMiamiSchoolofMedicine,Miami,Fla.AbstractBackgroundandPurpose—Acuteintracerebralhemorrhage(ICH)isacommonandsevereformofstroke.Todate,medicalmanagementofICHhashadscantimpactonmorbidityandmortality.Becausealbumintherapyismarke...
醫源資料庫;在線期刊;中風學雜誌;2005年第36卷第2期Effectofsimvastatinonhighglucose-andangiotensinII-inducedactivationoftheJAK/STATpathwayinmesangialcells
...alsofoundthattheactivationofJAK2byHGandANGIIwasdependentontheRhofamilyofGTPases.Consistentwiththeseinvitroresults,bothalbuminproteinexcretionandphosphorylationofJAK2,STAT1,andSTAT3wereattenuatedinrenalglomerulibyadministrationofsimvastatininastreptozotocin-inducedratmodelofHGdiabetes.Thisstudydemons...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第7期我國50年來蚊蟲防制研究概況
...llusthruringensis)的幾個血清型和球形芽抱桿菌(B.sphaericus,Bs.),是迄今殺滅幼蟲最有效和應用最廣的生物防制物。蘇雲金桿菌血清型14(Bt.H-14),即所謂以色列變種(var.israelensis),對我國埃及伊蚊(Aedesaegypti)、白紋伊蚊(Aed...
合作平臺;醫學論文;預防醫學與公共衛生學論文;流行病學SurfactantandPhysiologicResponsesofPretermLambstoContinuousPositiveAirwayPressure
...bstobreathesuccessfullyonaCPAPof5cmH2O(CPAP5).Fiveof21lambsdeliveredat130eC136daysgestationfailedtokeepPCO2below100mmHgby2hours.Thelambsthatfailedhadlessthan1.9eol/kgSatPCinbronchoalveolarfluid(approximately3%thepoolsizeatterm),lesssurfactantsecretion,andlesslargeaggregatesurfactant.Physiologicrespo...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第3期Coffeeandhomocysteine
...tspotentialadversehealtheffects.Reportshavelinkedcoffeeconsumptionwithincreasedriskofcardiovasculardisease,severalcancers,andpregnancycomplications(1).Today,thecombinedevidenceofilleffectsisratherweak,butpublicawarenessofthisdebatehasprobablycontributedtothedeclineincoffeeconsumption,atleastintheUni...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2000年71卷第2期超聲組織定徵對慢性乙型肝炎肝纖維化的量化研究
...isandconventionalultrasonographyindiffuseparenchymalandmaligˉnantliverdisease.JCU-J-Clin-Ultrasound,1985,13:87-99.6Garra-BS.Quantitativeultrasonicdetectionandclsssificationofdiffuseliverdisease.Comparisonwithhumanobserverperformance.Invest-Radiol,1989,24:196-203.7中華醫學會傳染病與...
合作平臺;在線期刊;中華實用醫藥雜誌;2004年第4卷第11期;論著糖尿病合併腦梗塞36例分析
...言不利7例,昏迷5例,偏癱14例,抽搐3例。實驗室檢查血:BS8~11.9mmol/L28例,12~25mmol/L8例;CH6.8~8.5mmol/L26例,8.6~19.5mmol/L10例;TG1.9~4.0mmol/L27例,4.1mmol/L9例。ECG示ST段水平下移0.5mV,T波低平及倒置14例,B超示脂肪肝25例。頭顱CT或MR...
合作平臺;在線期刊;中華醫學實踐雜誌;2004年第3卷第9期;經驗交流