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TheCablesGeneonChromosomeqIsSilencedbyPromoterHypermethylationandAllelicLossinHumanColorectalCancer
...Cablesisacyclin-dependentkinase-bindingnuclearproteinthatmapstochromosome18q11-12.Here,weassessedCablesexpressionin160colorectalcancers(CRCs),itsroleincoloncancercellgrowth,andthepotentialmechanismsofCablesinactivation.Expressionlevels,promotermethylation,andmutationalstatusofCableswereinvestigatedi...
醫源資料庫；在線期刊；美國病理學雜誌；2007年第169卷第11期 -
RegulationofGlutathioneSynthesisviaInteractionbetweenGlutamateTransport-AssociatedProtein3-18(GTRAP3-18)andExcitatoryAminoAcidCarrier-1(EAAC1
...ntinHEK293cells.Weexaminedtheeffectofglutamatetransport-associatedprotein3-18(GTRAP3-18),whichiscapableofinteractingwithEAAC1.TheGSHcontentdecreasedwhentheGTRAP3-18proteinlevelattheplasmamembranewasincreasedbymethyl--cyclodextrin(250µM),renderingthecellsmorevulnerabletooxidativestress.Intracel...
醫源資料庫；在線期刊；分子藥理學雜誌；2007年第69卷第11期 -
EndotoxinUp-regulatesInterleukin-18
...rT-celltype1–mediatedprocess.Previouslywedemonstratedaroleforinterleukin-18insarcoidosis.Hereweexaminetheregulationofinterleukin-18inthiscondition.Methods:CytokinelevelsinsarcoidepithelialliningfluidweremeasuredbyELISA.Weexaminedinterleukin-18promoteractivityandmRNAandproteinlevelsintheepitheliall...
醫源資料庫；在線期刊；美國呼吸和危急護理醫學；2005年第171卷第11期 -
Stathmin-deficientmicedevelopfibrosisandshowdelayedrecoveryfromischemic-reperfusioninjury
...heroleofstathminintherecoveryfromischemickidneyinjury,stathmin-deficient(OP18-/-)andwild-type(WT)animalsweresubjectedtoexperimentalIRI.At3,7,and14daysafterreperfusionserumsamplesandkidneyswerecollectedfortheexaminationofparametersofrenalfunction,morphology,andrecovery.Ourstudiesindicatethatonday14af...
醫源資料庫；在線期刊；美國生理學雜誌；2006年第289卷第6期 -
IL-18AcceleratesAtherosclerosisAccompaniedbyElevationofIFN-andCXCL16ExpressionIndependentlyofTCells
...-mailXinghua.Zhou@cmm.ki.seAbstractObjective—TheproatherogeniceffectofIL-18isshowntobedependentonIFN-production.ItisbelievedthatactivatedTcellsplayaproatherogenicrolethroughsecretionofIFN-.However,recentstudiesinvitrohaveshownthatmacrophages,NKcells,andevenvascularsmoothmusclecellsmayalsosecreteIF...
醫源資料庫；在線期刊；動脈硬化血栓血管生物學雜誌；2005年第25卷第4期 -
慢性重型肝炎患者血清IL-4、IL-18水平的觀察
...要】目的觀察慢性重型肝炎（慢重肝）患者血清IL-4、IL-18的變化，分析他們與慢重肝發病轉歸的關係。方法採用雙抗體夾心ELISA法測定血清IL-4、IL-18。結果慢性肝炎組、慢重肝組IL-4、IL-18顯著高於對照組（t=2.23，8.55;20.21，5.66，P=...
合作平臺；在線期刊；中華醫學研究雜誌；2004年第4卷第8期；論著 -
食管癌患者血清IL-2和IL-18測定和意義
【摘要】目的：IL-2和IL-18在腫瘤的免疫中的作用。方法：本研究使用ELISA法檢測了45名食管癌患者和30名健康志願者的外周血IL-2和IL-18水平。結果：食管癌患者的血清IL-2水平顯著低於健康志願者（P<0.05）與之相反食管癌患者的血...
醫源資料庫；在線期刊；中國民康醫學；2007年第19卷第7期 -
FunctionofHAb18G/CD147inInvasionofHostCellsbySevereAcuteRespiratorySyndromeCoronavirus
...Medicine,UniversityofCalifornia,SanDiego,SanDiegoToidentifythefunctionofHAb18G/CD147ininvasionofhostcellsbysevereacuterespiratorysyndrome(SARS)coronavirus(CoV),weanalyzedtheprotein-proteininteractionamongHAb18G/CD147,cyclophilinA(CyPA),andSARS-CoVstructuralproteinsbycoimmunoprecipitationandsurfacepl...
醫源資料庫；在線期刊；傳染病學雜誌；2005年第191卷第5期 -
Pheochromocytomas:Detectionwith18FDOPAWhole-BodyPETnitialResults
...Strasse55,79106Freiburg,Germany.ReceivedMarch16,2001;revisionrequestedApril18;revisionreceivedJuly17;acceptedAugust9. ABSTRACT：TopABSTRACTINTRODUCTIONMATERIALSANDMETHODSRESULTSDISCUSSIONREFERENCES：PURPOSE:Toevaluatefluorine18(18F)dihydroxyphenylalanine(DOPA)whole-bodypositronemissiontomography...
醫源資料庫；在線期刊；中風學雜誌；2001年第1卷第2期 -
Pheochromocytomas:Detectionwith18FDOPAWhole-BodyPET桰nitialResults1
...Strasse55,79106Freiburg,Germany.ReceivedMarch16,2001;revisionrequestedApril18;revisionreceivedJuly17;acceptedAugust9. ABSTRACTTopABSTRACTINTRODUCTIONMATERIALSANDMETHODSRESULTSDISCUSSIONREFERENCESPURPOSE:Toevaluatefluorine18(18F)dihydroxyphenylalanine(DOPA)whole-bodypositronemissiontomography(PET)a...
醫源資料庫；在線期刊；放射學雜誌；2003年1月第226卷第2期