肌苷對大鼠腦缺血再灌注後GAP43mRNA表達影響
...腦缺血再灌注後各時間點腦組織生長相關蛋白基因(GAP43mRNA)的表達。結果對照組於再灌注2h~7d、治療組於再灌注12h~7d,GAP43mRNA表達與假手術組比較明顯增多(t=2.70~29.84,P0.05),治療組與對照組比較GAP43mRNA表達於再灌注2h...
醫源資料庫;在線期刊;齊魯醫學雜誌;2006年第21卷第1期ImprovementoftheSpecificityofanEnzyme-LinkedImmunosorbentAssayforDiagnosisofParacoccidioidomycosis
...withPCMweretestedusingvariousapproaches,suchassodiummetaperiodateantigen(gp43)treatment,aserumabsorptionprocesswithCandidaalbicansorHistoplasmacapsulatumantigens,anddilutionofserumingalactose,themaincommonepitopeamongpathogenicfungi.ThemaximumspecificityfoundinthisELISAwas84%.Alloftheseprocedurespro...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第4期DiagnosisofNeuroparacoccidioidomycosisbyDetectionofCirculatingAntigenandAntibodyinCerebrospinalFluid
...roPCMwereanalyzedbyinh-ELISAfordetectionofcirculatingglycoproteinantigensof43kDa(gp43)and70kDa(gp70).Circulatinggp43andgp70antigensweredetectedinallCSFsamplesfrompatientswithneuroPCMatmeanconcentrationsof19.3and6.8μg/ml,respectively.Inaddition,bothgp43andgp70antigensweredetectedin10of11serumsamples...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第9期TDP-43蛋白積聚的機制
...化與細胞所胡紅雨課題組的研究論文。該論文闡明瞭TDP-43蛋白的降解片段TDP-35是其在細胞質內形成包涵體的主要原因,並且包涵體的形成引起該蛋白質參與RNA加工功能的改變。肌萎縮側索硬化症(AmyotrophicLateralSclerosis,ALS)和額顳葉...
行業資訊;臨牀快報;細胞分子與蛋白質組OxidizedPhospholipidsAlterVascularConnexinExpression,Phosphorylation,andHeterocellularCommunication
...rcellcocultures.OxPAPCappliedtocarotidsinducedanupregulationofbothCx37andCx43intheVSMC.InEC,Cx43wasupregulatedandCx37wasdownregulated,whereasCx40inECremainedconstant.Inthevascularcellcoculture,OxPAPCcausedsimilarchangesinCx37andCx43butcausedadecreaseinCx40inECandanelevationofCx40inVSMC.Inthecocultur...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第10期AdenovirusVectorE4GeneRegulatesConnexin40and43ExpressioninEndothelialCellsviaPKAandPI3KSignalPathways
...time-anddose-dependentinductionofjunctionalCx40expressionandsuppressionofCx43proteinandmRNAexpression.TreatmentofECswithPKAinhibitorH89orPI3KinhibitorLY294002preventedtheAdE4+-mediatedregulationofCx40andCx43thatwasassociatedwithdiminishedAdE4+-mediatedsurvivalofECs.Moreover,bothPKAactivityandcAMP-re...
醫源資料庫;在線期刊;循環研究雜誌;2005年第95卷第5期DetectionofCirculatinggp43AntigeninSerumCerebrospinalFluid,andBronchoalveolarLavageFluidofPatientswithParacoccidioidomycosis
...lse-negativeresults.Incontrast,thedetectionofParacoccidioidesbrasiliensisgp43circulatingantigenmayrepresentamorepracticalapproachtotherapiddiagnosisofthedisease.Accordingly,aninhibitionenzyme-linkedimmunosorbentassay(inh-ELISA)wasdevelopedforthedetectionofa43-kDaP.brasiliensis-specificepitopeincorpo...
醫源資料庫;在線期刊;微生物臨牀雜誌;2003年第41卷第8期DistinctPathwaysRegulateExpressionofCardiacElectricalandMechanicalJunctionProteinsinResponsetoStretch
...retch.Previously,weshowedthatexpressionofthegapjunctionprotein,connexin(Cx)43,isincreasedby2-foldafter1hourofstretch,andthisresponseismediatedbystretch-inducedsecretionofvascularendothelialgrowthfactor(VEGF).Here,wereportthatthemechanicaljunctionproteinsplakoglobin,desmoplakin,andN-cadherinarealsoup...
醫源資料庫;在線期刊;循環研究雜誌;2005年第95卷第8期DevelopmentofOne-Step,Real-Time,QuantitativeReverseTranscriptasePCRAssaysforAbsoluteQuantitationofHumanCoronavirusesOC43and229E
...CR(qRT-PCR)fortherapiddetectionandquantitationofhumancoronaviruses(HCoVs)OC43and229E.Absoluteviralloadmeasurementinclinicalsampleswasachievedthroughtheconstructionofin-houseHCoVOC43and229EcRNAstandardsforthegenerationofastandardcurve.TheHCoVOC43assayallowsquantitationoverarangefrom20to2x108RNAcopies...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第11期關於施行《進口藥材管理辦法(試行)》有關事宜的通知
...種目錄(第一批)序號名稱適用標準產地1兒茶《兒茶等43種進口藥材質量標準》印度尼西亞、馬來西亞、緬甸2西洋參《兒茶等43種進口藥材質量標準》加拿大、美國3高麗紅參《兒茶等43種進口藥材質量標準》韓國4西紅花《兒茶...
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