RolesfortheTrypanosomabruceiP2TransporterinDB75UptakeandResistance
【關鍵詞】RolesAnoveltrypanocide,2,5-bis(4-amidinophenyl)furan(DB75),initsprodrugamidoxime-derivativeform,2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime(DB289),isintrialsasthefirstorallyadministereddrugforhumanAfricantrypanosomiasis.DB75isadiamidine.Resistancetosomediamidinescorrelatestolo...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第11期UnderstandinghowcombinationsofHLAandKIRgenesinfluencedisease
S.R.andE.O.L.areatNationalInstituteofAllergyandInfectiousDiseases,NationalInstitutesofHealth,Rockville,MD20852.CombinationsofHLAandkillercellimmunoglobulin–likereceptor(KIR)geneshavebeenassociatedwithdiseasesasdiverseasautoimmunity,viralinfections,reproductivefailure,andnowcancer.Muchasearlyobserv...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第7期PCR-BasedDiagnosisofNeonatalStaphylococcalBacteremias
DepartmentsofNeonatologyInfectiousDiseasesEpidemiologyLaboratoryofClinicalMicrobiology,MeyerChildrensHospital—RambamMedicalCenter,andtheBruceRappaportFacultyofMedicine,Technion—IsraelInstituteofTechnology,Haifa,IsraelABSTRACTWecomparedPCRwithbloodculturesinthediagnosisofneonatalstaphylococcalsep...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第9期PhylogeneticAnalysisofthep24-p7RegionoftheHumanImmunodeficiencyVirusType1gagGeneToDetermineSubtypeDistributionamongFemaleSexWorkersinC
HIV/AIDSLaboratory,NationalInstituteofCholeraandEntericDiseasesSTD/HIVInterventionProject,Calcutta,IndiaABSTRACTHumanimmunodeficiencyvirustype1(HIV-1)subtypeC,basedontheenveloperegion,hasbeenreportedtobepredominantinIndia.Wesequencedthep24-p7gagregionfrom51HIV-1seropositivefemalesexworkersinCalcutta...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第11期Keratoconus:ananalysisofcornealasymmetry
1DepartmentofOptometry,UniversityofUlster,Coleraine,CoLondonderry,UK2DepartmentofOphthalmology,RoyalVictoriaHospitalBelfast,Belfast,UK3DepartmentofEpidemiologyandPublicHealth,Queen’sUniversity,Belfast,UK4DepartmentofOphthalmology,Queen’sUniversity,Belfast,UKABSTRACTBackground:Keratoconus,anon-in...
醫源資料庫;在線期刊;英國眼科學雜誌;2004年第88卷第10期MolecularEpidemiologyofClinicalCryptococcusneoformansStrainsfromIndia
DepartmentofMicrobiology,AllIndiaInstituteofMedicalSciences,NewDelhi,IndiaDepartmentofMicrobiology,UniversityofTexas,SanAntonio,TexasDepartmentofMedicineDepartmentsofMicrobiologyandImmunology,AlbertEinsteinCollegeofMedicine,Bronx,NewYorkIndianInstituteofScience,Banglore,IndiaInstituteforMolecularBio...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第11期Inheriteddisordersofvoltage-gatedsodiumchannels
DivisionofGeneticMedicine,DepartmentsofMedicineandPharmacology,VanderbiltUniversity,Nashville,Tennessee,USA.AbstractAvarietyofinheritedhumandisordersaffectingskeletalmusclecontraction,heartrhythm,andnervoussystemfunctionhavebeentracedtomutationsingenesencodingvoltage-gatedsodiumchannels.Clinicalseve...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第8期RateandIncidenceEstimatesofRecentHumanImmunodeficiencyVirusType1InfectionsamongPregnantWomeninSoPaulo,Brazil,from1991to2002
InstitutoAdolfoLutz,SecretariadeEstadodaSaúdeNationalProgramonSTDandAIDS,MinistryofHealth,SoPaulo,BrazilViralandRickettsialDiseaseLaboratory,CaliforniaDepartmentofHealthServices,Berkeley,CaliforniaABSTRACTTheserologicaltestingalgorithmforrecenthumanimmunodeficiencyvirus(HIV)seroconversion(STARHS)wa...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第3期Purifiedhematopoieticstemcellengraftmentofrarenichescorrectsseverelymphoiddeficiencieswithouthostconditioning
DepartmentofPathology,InstituteofCancerandStemCellBiologyandMedicine,StanfordUniversitySchoolofMedicine,Stanford,CA94305Intheabsenceofirradiationorothercytoreductiveconditioning,endogenoushematopoieticstemcells(HSCs)arethoughttofilltheuniquenicheswithinthebonemarrowthatallowmaintenanceoffullhematopo...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第1期CharacterizationofG-ProteinCoupledReceptorKinaseInteractionwiththeNeurokinin-1ReceptorUsingBioluminescenceResonanceEnergyTransfer
【關鍵詞】CharacterizationToanalyzetheinteractionbetweentheneurokinin-1(NK-1)receptorandG-proteincoupledreceptorkinases(GRKs),weperformedbioluminescenceresonanceenergytransfer2(BRET2)measurementsbetweenthefamilyANK-1receptorandGRK2andGRK5aswellastheirrespectivekinase-inactivemutants.Weobserveda...
醫源資料庫;在線期刊;分子藥理學雜誌;2008年第70卷第2期