TularemiainDenmark:IdentificationofaFrancisellatularensissubsp.holarcticaStrainbyReal-TimePCRandHigh-ResolutionTypingbyMultiple-LocusVariab
...,SundsvallHospital,Sundsvall,SwedenABSTRACTWereportulceroglandulartularemiaaffectingan8-year-oldboyandthefirstrecoveryofFrancisellatularensisinDenmark.Anovelreal-timePCRassaywasusedtoidentifythestrainasF.tularensissubsp.holarctica(typeB).Multiple-locusvariable-numbertandemrepeatanalysisdemonstrateda...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第10期TRAF-1,-2,-3,-5,and-6AreInducedinAtheroscleroticPlaquesandDifferentiallyMediateProinflammatoryFunctionsofCD40LinEndothelialCells
...nvestigatedtheinvolvementoftumornecrosisfactorreceptor-associatedfactors(TRAFs)inCD40signalinginendothelialcells(ECs)andtheirexpressioninatheromataandcellsinvolvedinatherogenesis.MethodsandResults-CD40LenhancedthebasalexpressionofTRAF-1,-2,-3,and6,butnotTRAF-5inECs.TRAFsassociatedwithCD40onligationb...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第5期雄黃的藥理學研究進展
...細胞信號傳遞蛋白類基因U51903和Z22533,DNA結合轉錄和轉錄因子相關基因AF036613、代謝類基因X66435等可能是雄黃作用於ADL的靶基因[16]。0.001μmol/L~0.100μmol/L濃度的雄黃可抑制HL-60/ADR細胞生長,逆轉其耐藥,促進細胞凋亡,與劑...
合作平臺;在線期刊;中華現代中西醫雜誌;2004年第2卷第11期;綜述InflammatoryBasisofExercise-inducedBronchoconstriction
...sputumwasusedtomeasuremastcellmediatorsandeicosanoidsatbaselineand30minutesafterexercisechallengein25individualswithasthmawithEIB.Inarandomized,double-blindcrossoverstudy,thecysteinylleukotrieneantagonistmontelukastandantihistamineloratadineortwomatchedplaceboswereadministeredfortwodosesbeforeexerci...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第9期ARIXgenepolymorphismsinpatientswithcongenitalsuperiorobliquemusclepalsy
...alsy)and54normalindividuals.PCRproductsclonedintoplasmidswerealsosequenced.Afamilywithfatherandadaughtereachhavingcongenitalsuperiorobliquemusclepalsywasalsoinvolvedinthisstudy.Results:FourpatientswithcongenitalsuperiorobliquemusclepalsycarriedheterozygousnucleotidechangesintheARIXgene.Onepatientwit...
醫源資料庫;在線期刊;英國眼科學雜誌;2004年第88卷第2期從四例丙肝患者系列血清標本分析HCV基因的變異
...ts.Duringtheswitchingperiodoftwogenotypes,2patientshadaco-infectionof1band2aforshortperiod.Allthetestedsampleswere1b,2aor1b+2a.Fivetonineclonesobtainedfromthesameserumweresequenced.Althoughsomenucleotidevariationwasfoundindifferentclones,only0.8-4.56of570nucleotidesweredifferent.Conclusions Co-inf...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學大鼠腰椎間盤針刺退變模型的建立△
...傷兔纖維環後不引起椎間盤退變,適合椎間盤中注射生長因子、質粒、藥物、細胞等物質;而Kim等〔7〕採用21G針刺3針比18G刺1針能夠更快的引起兔椎間盤退變;Sobajima等〔8〕採用16G針刺兔椎間盤,MRI在3周時發現椎間盤開始退變...
醫源資料庫;在線期刊;中國矯形外科雜誌;2007年第15卷第13期Predictingobesityinadultsfromchildhoodandadolescentweight
...lityofadultobesityforyoungfemaleswas4059.9%from5to12yofageand60%thereafter.Foryoungmales,theprobabilityofadultobesitywas2039.9%from4to12yofageand60%thereafter.Withtheincreasingepidemicofobesityintheworld(24),theabilitytoidentifyindividualsatanearlyagewhoareatahighriskofobesityispar...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2002年76卷第3期IdentificationofGeneticEvidenceforDobravaVirusSpilloverinRodentsbyNestedReverseTranscription(RT)-PCRandTaqManRT-PCR
...avirus(PUUV),andTulavirus(TULV)(6,16,21).DOBVwasoriginallyisolatedinSloveniafromtherodentApodemusflavicollis(DOBV-Af)(3)andisaEurasianhantavirusthatpredominantlycausesdiseaseinhumansinsoutheasternEurope.DOBV-AfhasalsobeenisolatedinGreece,Albania,andBosnia-Herzegovina(1,10,14).Serologicalstudieshavei...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第2期FluorogenicAssayforMolecularTypingoftheLeishmaniadonovaniComplex:TaxonomicandClinicalApplications
...d(1)2polymerasechainreactionstargetingthe2cysteineproteinasebisogenesand(2)afluorescence-resonanceenergytransfer/meltingcurveanalysisofthepolymorphismswithina31-ntregion.AllstrainswithintheL.donovanicomplexweredistinguishedfromL.tropica,L.major,andL.aethiopica,and5distinctgroupswereidentifiedwithint...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第16期