ModulationofSmoothMuscleCellMigrationbyMembersoftheLow-DensityLipoproteinReceptorFamily
...growthfactorprecursorhomologyrepeatswithaconsensustetrapeptide,Tyr-Trp-Thr-Asp,andinthecytoplasmicregion,signalsforreceptorinternalizationviacoatedpits.TheseLRsdiscoveredtodatearetheLDLreceptor,LDLreceptor-relatedprotein-1(LRP-1),megalin,theverylow-densitylipoprotein(VLDL)receptor/LR8,apolipoprotein...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第6期ActivationoftheCXCR3ChemokineReceptorthroughAnchoringofaSmallMoleculeChelatorLigandbetweenTM-III,-IV,and-VI
...aromaticchelatorsbipyridineorphenanthroleneincomplexwithZn(II)orCu(II)actedaspotentagonistsdisplayingsignalingefficaciessimilartoorevenbetterthantheendogenouschemokineagonists.Molecularmodelingandmolecularsimulationscombinedwithmutationalanalysisindicatedthatthemetalionsite-anchoredchelatorsactasago...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第3期ApoptosismodulatesprotectiveimmunitytothepathogenicfungusHistoplasmacapsulatum
...denexceededthatofcontrols.TreatmentofnaiveandH.capsulatum–immunemicewithcaspaseinhibitorsdecreasedapoptosisbutmarkedlyenhancedtheseverityofinfection.Administrationofaproapoptoticdoseofsuramindiminishedthefungalburden.TheincreasedburdeninrecipientsofacaspaseinhibitorwasassociatedwithelevationsinIL-...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第10期ANovelActin-BindingDomainonSlo1Calcium-ActivatedPotassiumChannelsIsNecessaryforTheirExpressioninthePlasmaMembrane
...acoliisusuallydammethylated).ThenickedvectorDNAcarryingthedesiredmutationswasproliferatedinE.coliJM109-competentcells.Thefidelityofallconstructs,includingpointmutants,wasconfirmedbysequencing.Mouseanti-myc9B11(CellSignalingTechnologyInc.,Danvers,MA)wasusedforimmunoblotanalysisandforconfocalmicroscop...
醫源資料庫;在線期刊;分子藥理學雜誌;2008年第70卷第2期ELISA檢測抗A族鏈球菌C多糖抗體及意義
【摘要】目的建立測定人體血清抗鏈球菌C多糖(ACHO,ASP)抗體的酶聯免疫(ELISA)方法,探討其臨牀價值。方法以胰蛋白酶消化後的整個鏈球菌細胞作包被抗原,建立測定血清抗-ACHO抗體的ELISA方法;用該法測定58例風溼熱和復發...
合作平臺;在線期刊;中華實用醫藥雜誌;2004年第4卷第6期;論著UltrasoundStimulatesCyclooxygenase-2ExpressionandIncreasesBoneFormationthroughIntegrin,FocalAdhesionKinase,Phosphatidylinositol3-Kinase,andAkt
...nbyUSstimulation.Materials.Rabbitpolyclonalantibodyforphosphor-FAK(Tyr397)waspurchasedfromUpstateBiotechnology(LakePlacid,NY).RabbitpolyclonalantibodyforCOX-2waspurchasedfromCaymanChemical(AnnArbor,MI).ProteinA/Gbeads,anti-mouseandanti-rabbitIgG-conjugatedhorseradishperoxidase,rabbitpolyclonalantibo...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第6期FromFatFightertoRiskFactor
...kinesaresecretedbyWAT,includingleptin,adipsin,acylation-stimulatingprotein(ASP),angiotensinogen,plasminogenactivatorinhibitor-1(PAI-1),adiponectin,resistin,variouscytokinesincludingGM-CSFandG-CSF,andsteroidhormones.1Consequently,WATpeptidehormonesandcytokinesareinvolvedinenergyhomeostasis,glucoseand...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第1期抗乙型病毒性肝炎新藥——阿德福韋酯
...的新核苷類藥物研究現狀及展望.http://wwww.bjdth.com/shownew.asp?newsid=591.4紀慶風.拉米夫定治療慢性乙型肝炎的療效評價.中華現代中西醫雜誌,2004,2(2):172-173.5侯金林,孫劍.阿德福韋酯治療拉米夫定耐藥患者的最新進展.中國醫學...
醫源資料庫;在線期刊;中華實用醫藥雜誌;2006年第6卷第11期哈爾濱市香坊區1997-2006年0~14歲兒童死亡原因分析
...XiangfangDistrictofHarbinforthefutureinterventions.MethodsDescriptivestudywasperformedthroughanalyzingthedeathsurveillancedataof0-14childreninXianfangDistrictofHarbinfrom1997to2006.ResultsItshowedthattheaverageannualmortalitywas68.82per100000,whilemortalityofboys(79.44per100000)washigherthanthat...
醫源資料庫;在線期刊;中國學校衛生;2008年第28卷第7期七十味珍珠丸聯合銀杏葉注射液治療腔隙性
...有關;③抗血栓作用:七十昧珍珠丸對腦缺血疾病有類似Asp的抗血栓作用,且效果強於阿司匹林。主要是抑制血小板的聚集粘附功能,改善血瘀大鼠的高凝狀態,使Hot及AI降低,使血液流變性改變,有利於防止血栓產生,對大腦...
合作平臺;醫學論文;中西醫結合論文;中醫中藥