Noaudiblewheezing:nuggetsandconundrumsfrommouseasthmamodels
J.A.B.andK.F.A.areatBrighamandWomen‘sHospital,HarvardMedicalSchool,Boston,MA02115.MousemodelsofThelpertype2(Th2)cell–biasedpulmonaryinflammationhaveelucidatedmechanismsofsensitization,celltraffic,andinducedairwayhyperresponsiveness(AHR).Nonetheless,mostmicelackintrinsicAHR,acentralpropertyofhuma...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第12期PTEN和P27蛋白在胃癌組織中表達與臨牀病理特徵的相關性
...著低於正常胃粘膜(100%,P<0.05);PTEN蛋白表達與分化程度(r=-0.2907,P<0.05)、浸潤深度(r=-0.2615,P<0.05)、淋巴結轉移(r=-0.2597,P<0.05)、臨牀分期(r=-0.2577,P<0.05)呈負相關。在胃癌中P27蛋白陽性率(41.54%)顯著低於正常胃粘膜(95%,P<0.05),...
醫源資料庫;在線期刊;濱州醫學院學報;2008年第31卷第1期兒童精神分裂症患者微小軀體異常與腦室擴大關係的研究
...中華精神科雜誌》-2007年40卷4期-217-221頁醫學空間(MEDcyber.com)3月26日消息,該項研究目的是探討兒童精神分裂症患者微小軀體異常(MPAs)與腦室擴大的關係。方法採用對168例兒童精神分裂症患者(患者組)進行軀體異常量表(W...
行業資訊;臨牀快報;精神心理疾病Suppressionofallergicairwayinflammationbyhelminth-inducedregulatoryTcells
1InstituteofImmunologyandInfectionResearch,UniversityofEdinburgh,Edinburgh,EH93JT,UK2CentreforInflammationResearch,UniversityofEdinburgh,Edinburgh,EH93JT,UKAllergicdiseasesmediatedbyThelpertype(Th)2cellimmuneresponsesarerisingdramaticallyinmostdevelopedcountries.ExaggeratedTh2cellreactivitycouldresu...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第9期Listeria-AssociatedArthritisinaPatientUndergoingEtanerceptTherapy:CaseReportandReviewoftheLiterature
DivisionofRheumatology,DepartmentofInternalMedicineIII,MedicalUniversityofVienna,Vienna,AustriaDivisionofRheumatology,MedicalUniversityofGraz,Graz,AustriaABSTRACTListeriosiscanbeacauseofinfectiousarthritis.Here,wepresentacaseofarticularlisteriosisinapatientwithrheumatoidarthritisreceivingtreatmentwi...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第5期EffectofischemicacuterenaldamageontheexpressionofCOX-2andoxidativestress-relatedelementsinratkidney
【摘要】Acuterenalfailure(ARF)isaclinicalsyndromecharacterizedbydeteriorationofrenalfunctionoveraperiodofhoursordays.TheprincipalcausesofARFareischemicandtoxicinsultsthatcaninducetissuehypoxia.Transcriptionalresponsestohypoxiacanbeinflammatoryoradaptivewiththeparticipationofthehypoxia-induciblef...
醫源資料庫;在線期刊;美國生理學雜誌;2007年第290卷第5期DevelopmentofaNewOligonucleotideArrayToIdentifyStaphylococcalStrainsatSpeciesLevel
INRA—CentredeClermont-Ferrand-Theix,UR370,Microbiologie,63122Saint-GenesChampanelleCentreHospitalo-Universitaire,LaboratoiredeBacteriologie,28placeHenriDunant,63001Clermont-Ferrand,FranceABSTRACTThegenusStaphylococcusismadeupof36validatedspecieswhichcontainstrainsthatarepathogenic,saprophytic,orus...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第8期瑞芬太尼與異丙酚靜脈複合麻醉臨牀研究
...。方法選擇需全麻擇期手術300例,隨機分爲瑞芬太尼組(R組)和芬太尼組(F組),每組150例。麻醉誘導用咪達唑侖0.06mg/kg、(R組)瑞芬太尼1.5μg/kg、(F組)芬太尼3μg/kg、萬可松0.1mg/kg、異丙酚1.5mg/kg,順序靜脈緩慢推注。麻醉維...
醫源資料庫;在線期刊;中華中西醫雜誌;2006年第7卷第5期FurincleavageactivatestheepithelialNa+channelbyrelievingNa+self-inhibition
【摘要】EpithelialNa+channels(ENaC)areinhibitedbyextracellularNa+,aprocessreferredtoasNa+self-inhibition.Wepreviouslydemonstratedthatmutationofkeyresidueswithintwofurincleavageconsensussitesin,oronesitein,blockedsubunitproteolysisandinhibitedchannelactivitywhenmutantchannelswereexpressedinXenopu...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第6期ImmuneresponsesandHIV:alittleorderfromthechaos
1D.O.isatUniversityofWisconsin-Madison,DepartmentofPathologyandLaboratoryMedicine,Madison,WI53711.2D.B.isatDepartmentsofImmunologyandMolecularBiology,TheScrippsResearchInstitute,LaJolla,CA92037.HIVisevolutiongonemadandbad.Thevirusinfectsapersonandrapidlydiversifiestobecomeahugeswarmofviruses,eachequ...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第3期