Hypoxia-inducedneutrophilsurvivalismediatedbyHIF-1–dependentNF-Bactivity
...rophageandRF/6Aretinallines(41,42),yetinteractionsbetweenHIFandNF-Barepoorlyunderstood.StudieslookingatthenonhypoxicinductionofHIFhaveshownanumberofindirectlinksbetweentheHIFandNF-Btranscriptionpathways.Inneuronalcells,aHIF-dependentup-regulationoferythropoietinhasbeendescribedtopreventexcitotoxin-i...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第1期IL-23drivesapathogenicTcellpopulationthatinducesautoimmuneinflammation
...cell–expressinghostdefensegenes.ThepreciseinvivofunctionofIL-23iscurrentlyunclear.ItscapacitytoinduceIL-17andotherproinflammatoryfactorsappearsimportantforneutrophilrecruitment(17)andgranulomaformation(19).However,whendysregulated,itcausesinflammatoryresponsesoftenassociatedwithautoimmunity.ThIL-1...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第2期LowConcentrationsofNitricOxideExertaHormeticEffectonMycobacteriumtuberculosisInVitro
...ssionofavirulentstrainofMycobacteriumtuberculosis.N.Engl.J.Med.338:633-639.Yu,K.,C.Mitchell,Y.Xing,R.S.Magliozzo,B.R.Bloom,andJ.Chan.1999.Toxicityofnitrogenoxidesandrelatedoxidantsonmycobacteria:M.tuberculosisisresistanttoperoxynitriteanion.Tuber.LungDis.79:191-198.作者:WilliamBenjaminBrugmannan...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第9期GlobalTrendsintheAntifungalSusceptibilityofCryptococcusneoformans(1990to2004)
...ards(NCCLS)referenceMICmethods(30),indicatingthatinvitroresistancetocommonlyusedantifungalagents(i.e.,amphotericinB,flucytosine,fluconazole,anditraconazole)remainsuncommonamongC.neoformansandhasnotincreasedwithtimeinthelastdecadeintheUnitedStatesandintheUnitedKingdom.Incontrast,Saretal.(44)reportani...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第5期四逆法
...後都是落在這個上面。比如昨天師父指導看的一個病人,一直強調的是必須要抓住土和水,抓住先後天,人手在這裏,收工也在這裏,這是他一直強調的。那麼這個極、這個合一、這個水土合德怎麼去體現呢?在用上面又怎麼體...
中醫中藥;經典研習UseofMolecularBeaconsforRapid,Real-Time,QuantitativeMonitoringofCytotoxicT-LymphocyteEpitopeMutationsinSimianImmunodeficiencyVirus
...evelhigherthanwasusedforSybrGreen.Thisarbitrarythresholdlevelwasdeterminedbyusingasamplewith1x104copiesofT47ImutantSIVmac239gagplasmid.WhentheappropriatebackgroundfluorescencethresholdwassetfortheQuasar670fluorescence,themolecularbeaconsignalforeachsamplewasfoundtobedirectlyproportionaltotheamountof...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第9期MultilocusSequenceTypingofKlebsiellapneumoniaeNosocomialIsolates
...,andamplifiedfragmentlengthpolymorphism(18,27).However,thesemethodsaremostlyusedforoutbreakinvestigationatthelocallevel,astheirinterlaboratoryreproducibilityisdifficulttoachieveandastheydonotgeneratehighlyinformativeandunambiguousdata.Ribotypingishighlyreproducible,especiallyinitsautomatedimplementa...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第8期InVitroMethodToStudyAntifungalPerfusioninCandidaBiofilms
...nvitrodiffusioncellbioassaysystem.Usingthismodel,theperfusionofthreecommonlyusedantifungalagents,amphotericinB,fluconazole,andflucytosine,wasinvestigatedinbiofilmsofthreedifferentCandidaspecies(i.e.,Candidaalbicans,Candidaparapsilosis,andCandidakrusei)thatweredevelopedonmicroporousfilters.Scanningel...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第2期PCR-BasedDiagnosisofNeonatalStaphylococcalBacteremias
...)andPCRtesting(0.2to0.5ml)inEDTA-containingtubes.Bloodcultureswereanalyzedbyusinganautomatedcontinuous-monitoringbloodculturesystem(Bac-T-Alert;Biomerieux,Marcyl‘Etoile,France).DNAwasextractedbyusingtheHighPurePCRtemplatepreparationkit(RocheDiagnosticsGmbH,Mannheim,Germany)accordingtothemanufactur...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第9期EvaluationoftheCOBASTaqMan48Real-TimePCRSystemforQuantitationofHepatitisBVirusDNA
...otheexistingCOBASAMPLICORHBVMONITORbasedonconventionalPCRtechnology.Thestudyused104samplesfromdifferentpatients.Nodifferenceswerefoundinthesensitivityofthetests.Therewasanexcellentcorrelationbetweenthesamplewithaviralloadwithinthedynamicrangeofthetwotests(r=0.938).TheCOBASTaqMantesthasawiderlinearra...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第7期