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AssessmentofvitaminB-12,folate,andvitaminB-6statusandrelationtosulfuraminoacidmetabolisminneonates
...otalserumhomocysteine(tHcy)hasbeenusedasanindicatorofintracellularvitaminB-12,vitaminB-6,andfolatestatusinadults,butdataforneonatesandinfantsarelacking.VitaminB-12deficiencymayhavefataleffectsonneurologicdevelopmentininfants;therefore,earlydiagnosisiscrucial.Objective:Ouraimwastoprovideareferenceran...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2000年72卷第3期 -
HBV感染者血清及PBMC培養上清IL-12水平的檢測及意義
...乙型肝炎、HBsAg攜帶者及正常人血清和PBMC培養上清液中IL-12水平，並探討其意義。方法應用FicollHypaque密度梯度離心法從肝素化血中分離外周血PBMC，用ELISA方法檢測血清及PBMC培養上清液IL-12水平。結果（1）血清IL-12檢測結果:急性...
合作平臺；在線期刊；中華實用醫藥雜誌；2004年第4卷第1期；其他 -
Homocysteine,vitaminB-12,andfolicacidandtheriskofcognitivedeclineinoldage:theLeiden85-PlusStudy
...TBackground:HighconcentrationsofhomocysteineandlowconcentrationsofvitaminB-12andfolicacidarefrequentlyobservedinsubjectswithdementia.Objective:Weassessedwhetherserumconcentrationsofhomocysteine,vitaminB-12,orfolicacidpredictcognitivedeclineinoldage.Design:Thiswasaprospective,population-based,longitu...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2005年82卷第4期 -
Interleukin12InducesT-CellRecruitmentIntotheAtheroscleroticPlaque
...patientswithacutecoronarysyndrome(ACS),spontaneouslyexpressinterleukin(IL)-12receptors,evenintheabsenceofantigenicstimulation.CD4+CD28eCIL-12R+cellsrespondedtoIL-12stimulationwiththeupregulationofthechemokinereceptorCCR5andtheC-typelectinreceptorCD161,bothimplicatedinregulatingtissuehomingofeffector...
醫源資料庫；在線期刊；循環研究雜誌；2006年第96卷第3期 -
DAP12(KARAP)amplifiesinflammationandincreasesmortalityfromendotoxemiaandsepticperitonitis
...hnology,JapanScienceandTechnologyAgency,Honcho4-1-8,Kawaguchi,Saitama332-0012,JapanDAP12(KARAP)isatransmembranesignalingadaptorforafamilyofinnateimmunoreceptorsthathavebeenshowntoactivategranulocytesandmonocytes/macrophages,amplifyingproductionofinflammatorycytokines.Contrastingwiththesedata,recents...
醫源資料庫；在線期刊；實驗醫學雜誌；2005年第202卷第3期 -
Folicacidfortification:ismaskingofvitaminB-12deficiencywhatweshouldreallyworryabout?
...ndencetoPVerhoef,UnileverFoodandHealthResearchInstitute,OliviervanNoortlaan120,3133ATVlaardingen,Netherlands.Seecorrespondingarticleonpage1187.MandatoryfortificationofflourwithfolicacidhasreducedthenumberofneuraltubedefectsinNorthAmerica(1).ThestudybyWyckoffandGanji(2)inthisissueoftheJournalsuggests...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2007年86卷第4期 -
HyperhomocysteinemiaandvitaminB-12deficiencyinelderlyusingTitleIIIcnutritionservices
...prevalenceofhyperhomocysteinemiaintheolderpopulationwithcoexistingvitaminB-12deficiencyisnotknown.Objective:TheobjectivewastodeterminetheprevalenceofhyperhomocysteinemiaandvitaminB-12deficiencyinelderlywhowereusingTitleIIIcnutritionservices,afterfolatefoodfortificationintheUnitedStates.Design:Demogr...
醫源資料庫；在線期刊；美國臨牀營養學雜誌；2003年77卷第1期 -
12/15LipoxygenaseMediatesMonocyteAdhesiontoAorticEndotheliuminApolipoproteinE-DeficientMiceThroughActivationofRhoAandNF-B
【摘要】Objectives-12/15lipoxygenase(12/15LO)hasbeenimplicatedasamediatorofinflammationandatherosclerosis.Inthecurrentstudy,weidentifiedmechanismsthroughwhich12/15LOmediatesmonocyte:endothelialinteractionsinvivoinapolipoproteinE-deficientmice(apoEKO),awell-characterizedmousemodelofatherosclerosi...
醫源資料庫；在線期刊；動脈硬化血栓血管生物學雜誌；2006年第26卷第6期 -
人IL-12的克隆、表達及生物活性的鑑定
人IL-12的克隆、表達及生物活性的鑑定中國免疫學雜誌1999年第1期第15卷分子與細胞免疫學作者：曲春楓 孫宗棠單位：中國協和醫科大學腫瘤研究所，北京100021關鍵詞：人IL-12；樹突狀細胞；DNA序列；生物學活性 中國圖書分...
合作平臺；醫學論文；臨牀醫學與專科論文；檢驗醫學 -
LowPenetranceBroadResistanceandFavorableOutcomeofInterleukin12Receptorß1Deficiency
...nicalChemistryandImmunology,LeedsGeneralInfirmary,LeedsLS13EX,UnitedKingdom12DepartmentofPediatrics,KingFaycalHospitalandResearchCenter,11211Riyadh,SaudiArabia13PediatricInfectiousDiseasesUnitandDepartmentofImmunology,Valld‘HebronHospital,08035Barcelona,Spain14PrimaryImmunodeficiencyUnit,Departmen...
醫源資料庫；在線期刊；美國病理學雜誌；2003年第162卷第3期