Ras-DependentRecruitmentofc-MycforTranscriptionalActivationofNucleophosmin/B23inHighlyMalignantU1BladderCancerCells
...edinU1cellscomparedwithU4cells.Moreover,c-Mycandnucleophosmin/B23wereincreasedinU1butnotinU4cellsuponserumstimulationfromquiescence.Likewise,onlyinU1cellscouldserumstimulatetranscriptionalactivityofnucleophosmin/B23promoterandc-Mycresponseelement.Theincreaseofnucleophosmin/B23promoteractivitycouldbe...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第10期Determiningbioavailabilityoffoodfolatesinacontrolledinterventionstudy
...ns.Tobroadlyrepresenttheextenttowhichnaturalfolatesareconjugatedinfoods,weused2naturalsourcesoffolate,spinach(50%polyglutamylfolate)andyeast(100%polyglutamylfolate).Design:Ninety-sixmenwererandomlyassignedaccordingtotheirscreeningplasmahomocysteine(tHcy)concentrationto1of4treatmentgroupsforaninterve...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年80卷第4期DrugResistanceEvolutionofaMycobacteriumtuberculosisStrainfromaNoncompliantPatient
...asanItalianmanwithahistoryofintravenousdrugabuse,inwhompulmonaryTBwasdiagnosedwhenhewas29yearsold.HepresentedattheUmbertoIHospitalinAncona,Italy,withfever,weakness,mildweightloss,cough,anddiffusecervicalandaxillaradenopathy.Achestradiographshowedpulmonaryinfiltratesinbothupperlobeswithextensivecavit...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第7期EndothelialL-SelectinLigandsinSinusMucosaduringChronicMaxillaryRhinosinusitis
...epercentageofvesselsexpressingendothelialsulfatedsialylLewisxepitopesincreasedduringchronicrhinosinusitiscomparedwithuninflamedcontroltissue,especiallyinpatientswithadditionalallergicrhinitis,anddecreasedinspecimensfromaspirin-intolerantpatientswithpreoperativeoralcorticosteroidtreatment.Inaddition,...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第6期TheNHLBILymphangioleiomyomatosisRegistry
...nsofclinicalcharacteristicsofsubjectswithlymphangioleiomyomatosishavebeenbasedonalimitednumberofpatients.Objectives:Todescribetheclinicalcharacteristicsofsubjectswithpulmonarylymphangioleiomyomatosis,bothsporadicandtuberoussclerosis–relatedforms.Methods:Overa3-yrperiod,from1998to2001,243subjectswi...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2006年第173卷第1期EmergenceofVirulentMethicillin-ResistantStaphylococcusaureusStrainsCarryingPanton-ValentineLeucocidinGenesinTheNetherlands
...nfectionsandnecrotizingpneumonia,eveninpreviouslyhealthyindividuals.WeassessedtheprevalenceofPVL-positiveMRSAinTheNetherlandsfortwoperiodsoftime:(i)1987through1995and(ii)2000and2002,anddeterminedtheircharacteristicsbyusingmultilocussequencetypingandstaphylococcalchromosomecassette(SCCmec)typing.Itwa...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第7期Breast-feedingprotectsagainstceliacdisease
...etarygluteninfluencetheriskofceliacdiseaseinchildhood.Design:Apopulation-basedincidentcase-referentstudyofSwedishchildren,627caseswithceliacdiseaseand1254referents,wasconducted;78%ofthematchedsetswereincludedinthefinalanalyses.Aquestionnairewasusedtoassesspatternsoffoodintroductiontoinfants.Modelswe...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2002年75卷第5期DimorphismintheP2Y1ADPReceptorGeneIsAssociatedWithIncreasedPlateletActivationResponsetoADP
...electedpolymorphismsandtheplateletresponsetoADP(0.1,1.0,and10μmol/L),assessedbywholebloodflowcytometricmeasurementoffibrinogenbindingtoactivatedglycoproteinIIb-IIIa,werethendeterminedin200subjects.FivepolymorphismswerefoundintheP2Y1geneand11intheP2Y12gene.Allpolymorphismsweresilent.AP2Y1genedimorph...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2005年第25卷第1期Interferon-InducesMajorHistocompatibilityClassIITransactivator(CIITA),WhichMediatesCollagenRepressionandMajorHistocompatibilityClassIIActivat
...seinexpressionofCIITAisoformI.ExpressionofCIITAIIIandIVcorrelateswithdecreasedcollagentypeIandincreasedMHCIIgeneexpression.ExogenousexpressionofCIITAI,III,andIV,intransientlytransfectedSMCs,repressescollagentypeIpromoters(COL1A1andCOL1A2)andactivatesMHCIIpromoter.LevelsofCIITAandRFX5increaseinthenuc...
醫源資料庫;在線期刊;循環研究雜誌;2006年第96卷第3期ComparisonofReal-TimePCRProtocolsforDifferentialLaboratoryDiagnosisofAmebiasis
...veevaluationsofdiagnosticassays.INTRODUCTIONClinicalfeaturesofamebiasis,causedbytheprotozoanparasiteEntamoebahistolytica,rangefromasymptomaticcolonizationtoamebicdysenteryandinvasiveextraintestinalamebiasis,mostcommonlyintheformofliverabscesses(24).TheWorldHealthOrganizationestimatesthatamebiasisiso...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第11期