CXCL-CXCREngagementIsRequiredforMigrationofCutaneousDendriticCells
...foundthatCXCR4washighlyexpressedonmigratedcutaneousDCsandthatitsligand,CXCL12,wasdetectedintheLYVE-1+lymphaticvesselsintheskin.FITC-inducedcutaneousDCmigrationintothedraininglymphnodeswasimpairedbythespecificCXCR4antagonist4-F-Benzoyl-TN14003.AmongFITC+cells,Langerin+LangerhanscellsandLangerinC(derm...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第10期EfficacyofBVitaminsinLoweringHomocysteineinOlderMen
...mparingtreatmentwithadailytabletcontaining2mgoffolate,25mgofB6,and400μgofB12orplacebo.Thestudygroupswerebalancedregardingage(mean±SD,78.9±2.8years),Bvitamins,andtHcyatbaseline.Results—Amongthe13%withB12deficiency,thedifferenceinmeanchangesintreatmentandcontrolgroupsfortHcywas6.74μmol/L(95%CI,3...
醫源資料庫;在線期刊;中風學雜誌;2006年第37卷第2期扁桃體周圍膿腫的治療應怎樣進行?
...金銀花15g,野菊花15g,蒲公英15g,紫花地丁15g,紫背天葵12g,荊芥12g,防風10g,白芷10g。若腫痛甚者,可加射干12g,天花粉15g;咳嗽者可加枇杷葉10g,冬桑葉12g。(2)邪熱傳裏:膿未成,起病日久,高熱不退,頭痛劇烈,口乾喜飲...
醫源資料庫;醫源圖書館;疾病類;耳鼻咽喉疾病防治284問Dietaryconjugatedlinoleicacidandbodycomposition
...mercialpreparationscontainapproximatelyequalamountsofc9,t11andtrans-10,cis-12(t10,c12)isomers.StudieshaveshownthatCLA,specificallythet10,c12-isomer,canreducefattissuedepositionandbodylipidcontentbutappearstoinduceinsulinresistanceandfattyliverandspleeninvariousanimals.AfewhumanstudiessuggestthatCLAs...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年79卷第6期治療胃痛“七原則”
...芍30克,甘草10克,肉桂10克,吳茱萸6克,白芷50克,青皮12克,陳皮12克,枳殼12克,蒼朮12克,白朮12克,半夏12克,7劑。11月27目二診:胃痛止,易飢消。上方加香附12克,高良薑12克,再予’劑以資鞏固。本案芍藥甘草湯緩...
中醫中藥;中醫臨牀;臨牀討論ApolipoproteinESuppressestheTypeIInflammatoryResponseInVivo
...invivo.Theproinflammatorycytokinestumornecrosisfactor,interleukin(IL)-6,IL-12,andinterferon-wereupregulatedtoasignificantlygreaterextentinapoE-deficientmicethaninwild-typemiceatboththemRNAandproteinlevelsfollowingadministrationofLPS.Incontrast,hypercholesterolemiclow-densitylipoproteinreceptor/apobe...
醫源資料庫;在線期刊;循環研究雜誌;2005年第95卷第10期ReplytoRJBerryetal
...them.AmericanseniorshavebeenofparticularconcernnotonlybecausetheirvitaminB-12statusislow,butalsobecausetheirconsumptionoffortifiedbreakfastcerealsandsupplementsishigh(2).Consequently,Americanseniorsareathighriskofexceedingtheselectedlimitof1mgfolicacid/d,includingthatinsupplements,enrichedcereal-gra...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年86卷第1期Breakfastcerealfortifiedwithfolicacid,vitaminB-6,andvitaminB-12increasesvitaminconcentrationsandreduceshomocysteineconcentrations:arandomiz
...sedtheeffectofbreakfastcerealfortifiedwithfolicacid,vitaminB-6,andvitaminB-12onvitaminandhomocysteinestatus.Design:Arandomized,double-blindtrialwasconductedin189volunteersaged5085y.Thesubjectshadnohistoryofhypertension,anemia,asthma,cancer,orcardiovascularordigestivediseaseanddidnotregularlyco...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年79卷第5期DistinctRolesforProteinKinaseCIsoformsinRegulatingPlateletPurinergicReceptorFunction
...on,mediatingitsactionsthroughtwoGprotein-coupledreceptors(GPCRs),P2Y1andP2Y12.Wehaveshownpreviouslythatthereceptorsarefunctionallydesensitized,inahomologousmanner,bydistinctkinase-dependentmechanismsinwhichP2Y1isregulatedbyproteinkinaseC(PKC)andP2Y12byGprotein-coupledreceptorkinases.Inthisstudy,wead...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第9期ADPReceptorP2Y12IsExpressedinVascularSmoothMuscleCellsandStimulatesContractioninHumanBloodVessels
...RACTObjective—ADPplaysanimportantroleinplateletaggregationbyactivatingP2Y12receptors.WeassessedthehypothesisthatP2Y12receptorsareexpressedinvascularsmoothmusclecells(VSMC).MethodsandResults—P2Y12receptormRNAwasfoundtohaveahighexpressionamongtheP2receptorsinhumanVSMC,significantlyhigherthantheoth...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第10期