AtherosclerosisSusceptibilityLociIdentifiedFromaStrainIntercrossofApolipoproteinE-DeficientMiceviaaHigh-DensityGenomeScan
...andF2micederivedfromintercrossingthesestrains(Figure1Aand1B).AspreviouslyobservedinapoE-deficientmice,9femalemiceontheDBA/2andAKRbackgroundshavelargerlesionsintheaorticrootthanmalemice(P<0.01byMannWhitneytestforDBA/2andAKRparentalstrains).Female11-foldlargerthanlesionsinthefemaleAKRmice(P<0.001).The...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第3期Soyproteincontainingisoflavonesdoesnotdecreasecolorectalepithelialcellproliferationinarandomizedcontrolledtrial
...7antibodyimmunohistostaininghasbecomeavailableforlabelingproliferationinpreservedtissues.Ki-67isanendogenousnuclearproteinassociatedwiththecellcycle.TheKi-67antibodyidentifiescellsinthecyclingphasesbutnotintherestingphase(G0)orearlyphase(G1)(22,23).Ki-67labelingisconsideredtohaveseveraladvantagesove...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2005年82卷第3期ContributionofKvChannelstoPhenotypicRemodelingofHumanUterineArterySmoothMuscleCells
...etone.4MembranedepolarizationopensCavandraises[Ca2+]i,andcytosolic-freeCa2+serves,inturn,asacriticalsignaltransductionelementinavarietyofcellfunctions,suchascontraction,migration,proliferation,andgeneexpression.6eC8ThereisincreasingevidenceshowingthatK+channelsmayhaveanimportantroleindedifferentiati...
醫源資料庫;在線期刊;循環研究雜誌;2005年第95卷第12期Effectsofbeef-andfish-baseddietsonthekineticsofn-3fattyacidmetabolisminhumansubjects
...edinTable1.AllmealsduringtheexperimentaldietphasesofthestudywerepreparedandservedinthemetabolicresearchkitchenoftheClinicalCenter.Foodsourceswereconsistentthroughoutthestudy.Oralingestionofthedeuterium-labeledfattyacidsoccurredatthebeginningofthethird,sixth,andninthweeksafterthestudybegan,andbloodsa...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2003年77卷第3期RegularconsumptionofNaFeEDTA-fortifiedfishsauceimprovesironstatusandreducestheprevalenceofanemiainanemicVietnamesewomen
...ncesInstituteCenterforHealthPromotion.3AddressreprintrequeststoJBerger,IRD,Serviceculturel,AmbassadedeFrance,57TranHungDao,Hanoi,Vietnam.E-mail:j.berger{at}fpt.vn.ABSTRACTBackground:FishsauceisconsumeddailybyalargeproportionoftheVietnamesepopulationandcouldthereforebeapotentiallyusefulfoodvehiclefor...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2003年78卷第2期Alterationsinneurogenicallymediatedcontractileresponsesofurinarybladderinratswithdiabetes
...ireddetrusorcontractility(5).However,the“classic“symptomsarenotalwaysobservedinthediabeticpatientsandthesepatientsoftendemonstratevariedsymptompresentations.Recentstudieshaveshownthaturinaryfrequencyandurgencywithdetrusoroveractivityalsooccur(25,38).ThetraditionaltheorypostulatedthattheDBDattrib...
醫源資料庫;在線期刊;美國生理學雜誌;2005年第288卷第6期Intakesofenergyandmacronutrientsandtheriskofbenignprostatichyperplasia
...,Baltimore(EAP).Seecorrespondingeditorialonpage605.2SupportedbyPublicHealthServicegrantsDK45779andCA55075fromtheDepartmentofHealthandHumanService,theNationalInstitutesofHealth.3AddressreprintrequeststoEGiovannucci,DepartmentofNutrition,HarvardSchoolofPublicHealth,665HuntingtonAvenue,Boston,MA02115.E...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2002年75卷第4期P-SelectinGlycoproteinLigand-1IsExpressedonEndothelialCellsandMediatesMonocyteAdhesiontoActivatedEndothelium
...control).Nodetectabledifferencesbetweenstimulatedandunstimulatedcellswereobserved.AsapositivecontrolforTNForIL-1ßstimulationweanalyzedintercellularadhesionmolecule-1(ICAM-1)mRNAwhichshowedadramaticincreaseinexpressioninresponsetothesecytokines(datanotshown).Quantitativereal-timePCRdidnotshowsi...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第5期GlutathioneS-transferaseM1polymorphismandmetabolismofsulforaphanefromstandardandhigh-glucosinolatebroccoli
...omthestudybyLinetal(3)inwhichasignificantreductionincolorectaladenomaswasobservedonlyinGSTM1-positivesubjectswhoconsumedoneportionofbroccoli/wk,althoughbothGSTM1-positiveand-nullsubjectshadareducedincidenceofadenomaswithhigherbroccoliintakes.Incontrast,studiesconductedinAsiathatestimatedcrucifercons...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2005年82卷第6期RoleofOsteoprotegerininArterialCalcification
...rtainOPG(–/–)mice.Underelectronmicroscopy,calciumdepositswereobservedinthecytoplasmandextracellularmatrixofvascularsmoothmusclecells(VSMCs).NeitherapoptosisofVSMCsnorinfiltrationofmacrophageswasobserved.Alkalinephosphatase(ALP)activityofaortictissuecorrelatedwiththecalcifiedlesionarea.Mo...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第9期