AtypeIinterferonautocrine–paracrineloopisinvolvedinToll-likereceptor-inducedinterleukin-12p70secretionbydendriticcells
...niversity,Montreal,QuebecH3T1E2,CanadaDendriticcells(DC)produceinterleukin-12(IL-12)inresponsetoToll-likereceptor(TLR)activation.TwomajorTLRsignalingpathwaysparticipateintheresponsetopathogens:thenuclearfactor-B(NF-B)–dependentpathwayleadingtoinflammatorycytokinesecretionincludingIL-12andtheinterf...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第9期Folicacidfortification:thegood,thebad,andthepuzzleofvitaminB-
...rproductsintheUnitedStatesbefortifiedwithfolicacid(pteroylglutamicacid)R12;asubstanceformingonlyaveryminorcomponentofthefolatesinunfortifiedfood(2).Theargumentthenwasthatrandomizedclinicaltrialshadproventhatfolicacidtakeninveryearlypregnancycanmarkedlyreducetheriskthataninfantwillbebornwithaneura...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年85卷第1期DifferentialRegulationandRelocalizationofthePlateletP2YReceptorsafterActivation:AWaytoAvoidLossofHemostaticProperties
...epresentstudy,weinvestigatedthedesensitizationandtraffickingoftheP2Y1andP2Y12receptorsafteragonist-inducedstimulationofplateletsorastrocytomacellstransfectedwiththeP2Y1orP2Y12receptorsfusedtogreenfluorescentprotein.Inplateletsandintransfectedcells,exposureto10eADPcauseddesensitizationoftheP2Y1recept...
醫源資料庫;在線期刊;分子藥理學雜誌;2005年第67卷第3期MethylmalonicacidandcognitivefunctionintheMedicalResearchCouncilCognitiveFunctionandAgeingStudy
...142EN.E-mail:andrew{at}mccaddon.demon.co.uk.Seecorrespondingeditorialonpage1259.ABSTRACTBackground:Anelevatedbloodconcentrationofhomocysteineisanestablishedriskfactorforcognitiveimpairmentanddementia,butassociationsbetweencognitionandmethylmalonicacid(MMA),arelatedmetabolicmarkerofvitaminB-12deficie...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2006年84卷第6期LowvitaminB-12statusandriskofcognitivedeclineinolderadults
...fCFASbygrantsfromtheEuropeanUnion(QLK3-CT-2002-01775),HealthFoundation(554/1236),FoodStandardsAgency.andtheClothWorkersFoundation.JBwasalsosupportedbytheJoanDawkinsFellowshipoftheBritishMedicalAssociation.Alltheanalyseswereperformedindependentofthesourcesofsupport.3Reprintsnotavailable.Addresscorres...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年86卷第5期BiochemicalindexesoftheBvitaminsincordserumarepredictedbymaternalBvitaminstatus
...ionoftotalhomocysteine(tHcy)ishigherinnewbornsthaninolderchildren.VitaminB-12isthemajordeterminantoftHcyinnewborns.Maternalstatusoffolate,vitaminB-12,andvitaminB-6duringpregnancymayaffectthebiochemicalmarkersofthesemicronutrientsinnewborns.Objective:Ourobjectivewastostudytherelationbetweenconcentrat...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2005年82卷第1期孔少華治療眩暈醫案
...滑而數,宜以清平抑化和調。生牡蠣15g生石決明30g生赭石12g旋復花12g(布包)桑寄生30g炒知柏各10g霜桑葉10g杭菊花10g白蒺藜10g川牛膝15g龍膽草10g白殭蠶10g朱茯苓30g滑石塊15g法半夏10g荷葉10g全瓜蔞30g羚羊粉0.3g(分衝)[按]孔老認爲...
求醫問藥;專家門診;名家醫案補瀉兼施以氣爲先
...g,丹蔘20g,黃芪20g,當歸20g,熟地黃15g,川芎6g,枸杞子12g,菟絲子12g,覆盆子12g,巴戟天12g,仙靈脾12g,肉蓯蓉12g,制香附12g,川楝子12g。12劑,水煎服,每日2次。二診:2006年3月18日。Lmp:2月23日,BBT上升6天(最高36.7℃),...
求醫問藥;專家門診;名家醫案沈鳳閣教授雜病治驗3則
...納正常,苔薄白。治以祛風涼營解毒止癢,處方:細荊芥12g,防風12g,生地10g,粉丹皮10g,炒赤芍10g,生甘草5g,淨蟬衣12g,白鮮皮12g,地膚子12g,白薇12g,刺蒺藜12g,7劑。 二診:大部分紅疹消失,仍有少量紅疹新起,苔少...
求醫問藥;專家門診;名家醫案Opposingeffectsofcis-9,trans-11andtrans-10,cis-12conjugatedlinoleicacidonbloodlipidsinhealthyhumans
...of3dosesofhighlyenrichedcis-9,trans-11(0.59,1.19,and2.38g/d)ortrans-10,cis-12(0.63,1.26,and2.52g/d)CLApreparationsonbodycomposition,bloodlipidprofile,andmarkersofinsulinresistanceinhealthymen.Design:Healthymenconsumed1,2,and4capsulessequentially,containingeither80%cis-9,trans-11CLAor80%trans-10,cis-...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年80卷第3期