ResurrectionofvitaminDdeficiencyandrickets
...hcenturywascausedbyvitaminDdeficiencyduetoinadequatesunexposureandresultedingrowthretardation,muscleweakness,skeletaldeformities,hypocalcemia,tetany,andseizures.TheencouragementofsensiblesunexposureandthefortificationofmilkwithvitaminDresultedinalmostcompleteeradicationofthedisease.VitaminD(whereDre...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第8期Egr-1啓動子基因調控FLT3配基基因表達的實驗研究
...esontheexpressionofFLT3LigandregulatedbyEgr-1regulatedsequenceDUNa,LUOCheng-ji,ZOUZhong-min (InstituteofCombinedInjury,theThirdMilitaryMedicalUniversity,Chongqing400038,China) PEIXue-tao,LILiang,FENGKai,BAICi-xian (DepartmentofExperimentalHematology,Instituteof...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學Y染色體追蹤人類亞當
...男性的Y染色體的ZFY基因區,38人的DNA序列竟然完全相同。然而,這38名男性根本沒有任何親戚關係,難道這些男人是過去某個帝王巡遊或征戰世界(如成吉思汗)在各地留下的後裔?ZFY基因即鋅指基因(zinc-finger-Ygene,ZFY),有一百...
醫藥經濟;生物技術;技術要聞LeptinPromotesVascularRemodelingandNeointimalGrowthinMice
...CardiologyandPulmonaryMedicine(K.S.,M.H.,C.G.,M.P.,S.K.),UniversityofGoettingen,Goettingen,Germany,andtheDepartmentofCellBiology(C.D.,D.J.L.),DivisionofVascularBiology,TheScrippsResearchInstitute,LaJolla,Calif.CorrespondencetoStavrosKonstantinides,MD,DepartmentofCardiologyandPulmonaryMedicine,GeorgA...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第1期StromalCell-DerivedFactor-1InducesMatrixMetalloprotease-13ExpressioninHumanChondrocytes
...etalloproteinase(MMP)-13maycontributetothebreakdownofarticularcartilageduringarthritis.Here,wefoundthatSDF-1increasedthesecretionofMMP-13inculturedhumanchondrocytes,asshownbyreversetranscriptase-polymerasechainreaction,Westernblot,andzymographicanalysis.SDF-1alsoincreasedthesurfaceexpressionofCXCR4r...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第9期NovelRolesofLocalInsulin-LikeGrowthFactor-ActivationinGastricUlcerHealing
【摘要】Thepreciseroleofinsulin-likegrowthfactor(IGF)-1ingastriculcerhealingisunknown.Inexperimentalratgastriculcers,weexaminedexpressionofIGF-1mRNAandproteinbyreversetranscriptase-polymerasechainreactionorenzyme-linkedimmunosorbentassayandimmunostaining,respectively.Inculturedratgastricepitheli...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第4期Animalproteinintake,seruminsulin-likegrowthfactorI,andgrowthinhealthy2.5-y-oldDanishchildren
...iksberg,Denmark.E-mail:cho{at}kvl.dk.ABSTRACTBackground:Studiesfromdevelopingcountriesindicatethatintakeofanimalprotein,especiallyofmilk,isassociatedwithgreatervelocityoflineargrowthinchildhood.Whetherthesameassociationexistsinindustrializedcountries,whereproteinintakeishigh,isnotclear.Objective:Our...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年80卷第2期高效液相色譜法測定維參鋅膠囊中維生素E的含量
...:維生素E的最低檢測濃度爲0.1μg*mL-1,最低檢出量約爲2ng(0.1008μg*mL-1×20μL≈2ng)。2.4 回收試驗 分別精密稱取維生素E適量與處方量的輔料混合均勻,按“樣品測定”項下方法制得供試品溶液進行測定,計算回收率。測得5次平...
藥品天地;專業藥學;實驗技術;色譜技術;色譜分析實例SuppressionofActivationofSignalTransducerandActivatorofTranscription-BSignalingintheVesselWallReducesBalloonInjury-InducedNeointimaFormatio
...VSMC)growthandmotility.TolearnmoreabouttheroleofSTAT-5Binvesselwallremodeling,weexamineditsinvolvementinplatelet-derivedgrowthfactor-BB(PDGF-BB)-stimulatedVSMCgrowthandmotilityandballooninjury-inducedneointimaformation.PDGF-BBactivatedSTAT-5Basmeasuredbyitstyrosinephosphorylation,DNAbinding,andrepor...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第10期厭食症患者相對於健康體重婦女雄性激素顯著地較低
...遊離睾固酮濃度同樣有差異(0.32相較於0.47ng/dl;P0.05);然而,使用口服避孕藥物厭食症病患相較於健康控制組,其DHEA濃度並無差異(155相較於176ng/dl)。 雄性激素濃度,特別是遊離睾固酮、總睾固酮與DHEA,雖然程度...
行業資訊;臨牀快報;內分泌代謝