AlteredL-selectinexpressioninlymphocytesandincreasedadhesiontoendotheliuminpatientswithdiabeticretinopathy
...al,InvernessIV23UJ,UKABSTRACTAim:ToinvestigateL-selectinexpressionandsheddinginpatientswithandwithoutretinopathyandtodetermineifanyobservedchangesarereflectedbyafunctionalchangeintheadhesionofleucocytestoanendothelialmonolayer.Methods:Agematcheddiabeticpatients(26withretinopathy,19withoutretinopathy...
醫源資料庫;在線期刊;英國眼科學雜誌;2004年第88卷第9期NSE及其半衰期診斷與監測小細胞肺癌的評價
...n-specifcenolaseanditshalf-lifeanalysisindiagnosisandfollow-upofsmallcelllungcancerQIWei-min,CHENJie,JIANGnan-yan,GUOLi(DepartmentofClinicalLaboratory,theforthMilitaryMedicalUniversityh,Tang-duHospital,Xian710038,China) Abstract:Obiectivetoevaluatetheclinicalvalueofdetectionofserumneuron-...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學InhibitionofTumorNecrosisFactor--InducibleInflammatoryGenesbyInterferon-IsAssociatedwithAlteredNuclearFactor-BTransactivationandEnhancedHist
...cellsintheinitiationand/orperpetuationofairwayinflammationinasthmabyproducingvariousinflammatorychemokinesorcytokines.Previousstudiesfromourlaboratoryandothersshowedthatthecombinationoftumornecrosisfactor-(TNF)andinterferon-(IFN)orendogenousIFNresultsinasynergisticinductionofvariouspro-inflammatoryg...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第2期皮膚創傷癒合過程中基質細胞衍生因子1表達及其影響因素
...皮膚成纖維細胞,分別用不同濃度的TNFα和IL1(均爲0.1ng/ml、1ng/ml、10ng/ml、100ng/ml)作用於成纖維細胞48h後收穫細胞,通過RTPCR法檢測細胞SDF1α的基因表達。結果RTPCR結果發現成年鼠創傷癒合過程中創面SDF1呈雙峯表達,在損...
醫源資料庫;在線期刊;成都醫學院學報;2010年第5卷第3期AS擴血管機制的研究
...作用。 關鍵詞AS胸主動脈環磷酸核苷酸 StudingforthemechanismofphysiollingvessoofAS ZhangQuan,XuJingfeng The266thHospitalofPLA,Chengde,067000. 【Abstract】ObjectiveThemechanismofphysiollingvessolofASwasreserchedbythemothedofdectinginˉdenticalcontr...
合作平臺;在線期刊;中華實用醫藥雜誌;2004年第4卷第17期;論著CD44isadeterminantofinflammatoryboneloss
...mentalTraumaSurgery,UniversitySchoolofHamburg,D-20146Hamburg,Germany6BoehringerIngelheim,A-1121Vienna,Austria7ResearchInstituteofMolecularPathology,A-1030Vienna,AustriaChronicinflammationisamajortriggeroflocalandsystemicboneloss.Disintegrationofcell–matrixinteractionisaprerequisitefortheinvasionof...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第6期IncreasedMelanomaGrowthandMetastasisSpreadinginMiceOverexpressingPlacentaGrowthFactor
...cularendothelialgrowthfactorfamily,playsanimportantroleinadultpathologicalangiogenesis.TofurtherinvestigatePlGFfunctionsintumorgrowthandmetastasisformation,weusedtransgenicmiceoverexpressingPlGFintheskinunderthecontrolofthekeratin14promoter.Theseanimalsshowedahypervascularizedphenotypeoftheskinandin...
醫源資料庫;在線期刊;美國病理學雜誌;2006年第168卷第8期StromalFibroblastsinColorectalLiverMetastasesOriginateFromResidentFibroblastsandGenerateanInflammatoryMicroenvironment
...ocatedliverfibroblasts(LFs).WedemonstratedthatCLMsareinflammatorysitesshowingstromalexpressionofinterleukin-8(IL-8),achemokinerelatedtoinvasionandangiogenesis.InvitroanalysesrevealedastrikinginductionofIL-8expressioninCAFsandLFsbytumornecrosisfactor-(TNF-).TheeffectofTNF-onCAFsisinhibitedbythenuclea...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第11期丙戊酸鈉、託吡酯誘導癲癎患者體重及血清瘦素水平的變化
...丙戊酸鈉治療者體重增加(≥4kg),血清瘦素水平[(13.2±3.6)ng/ml]高於治療前[(7.4±3.0)ng/ml,P<0.01];6例託吡酯治療者體重減輕(≥4kg),血清瘦素水平[(3.7±1.8)ng/ml]低於治療前[(7.4±2.6)ng/ml,P<0.01]。可見經丙戊酸鈉治療體重增加者出現瘦...
行業資訊;臨牀快報;神經科肥胖兒童中瘦素與代謝綜合徵的關係
...水平。結果顯示,女孩的瘦素水平要明顯高於男孩(11.0ng/dlvs8.25ng/dl,P=0.007)。雖然代謝綜合徵患兒的瘦素水平要高於非代謝綜合徵者(11.3ng/dlvs8.9ng/dl,P=0.045),但在校正了性別這一因素後,該差異則不存在。研究人員指出,...
行業資訊;臨牀快報;小兒科