Identifyingprotein–proteininteractionsinsomatichypermutation
aM.F.G.isatUniversityofSouthernCalifornia,LosAngeles,CA90089.bM.D.S.isatAlbertEinsteinCollegeofMedicine,Bronx,NY10461.Somatichypermutation(SHM)inimmunoglobulingenesisrequiredforhighaffinityantibody–antigenbinding.Culturedcellsystems,mousemodelsystems,andhumangeneticdeficiencieshavebeenthekeyplayer...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第4期RelationshipbetweentheOriginalMultiplyResistantSouthAfricanIsolatesofStreptococcuspneumoniaefrom1977to1978andContemporaryInternationalResis
InstituteofMedicalMicrobiology,NationalReferenceCentreforStreptococci,Aachen,GermanyUniversityHospitalsofClevelandandCaseWesternReserveUniversity,Cleveland,Ohio44106HersheyMedicalCenter,Hershey,Pennsylvania17033ABSTRACTHigh-levelpenicillinG-resistantaswellasmultidrug-resistantStreptococcuspneumoniae...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第12期ComparisonofTwoHumanImmunodeficiencyVirus(HIV)RNASurrogateAssaystotheStandardHIVRNAAssay
RushMedicalCollege,Chicago,IllinoisUniversityofNorthCarolinaatChapelHill,ChapelHill,NorthCarolinaTheMacfarlaneBurnetInstituteforMedicalResearchandPublicHealth,Melbourne,AustraliaNewEnglandResearchInstitute,Watertown,MassachusettsUniversityofZurich,Zurich,SwitzerlandUniversityofWitwatersrandandNation...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第12期EvidenceofBorreliaAutoimmunity-InducedComponentofLymeCarditisandArthritis
DepartmentsofPathologyandMedicine,NewJerseyMedicalSchool,UniversityofMedicineandDentistryofNewJersey,Newark,NewJerseyDepartmentofMolecularGeneticsandMicrobiology,UniversityofNewMexico,Albuquerque,NewMexicoUniversityofOklahomaHealthSciencesCenter,OklahomaCity,OklahomaABSTRACTWeinvestigatedthepossibil...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第2期PresenceofActivatableShigaToxinGenotype(stx2d)inShigaToxigenicEscherichiacolifromLivestockSources
FoodScienceAustralia,TingalpaDC,Queensland4173,AustraliaReceived4February2003/Returnedformodification21March2003/Accepted14April2003 ABSTRACTTopAbstractIntroductionMaterialsandMethodsResultsDiscussionReferencesStx2disarecentlydescribedShigatoxinwhosecytotoxicityisactivated10-to1,000-foldbytheelast...
醫源資料庫;在線期刊;微生物臨牀雜誌;2003年第41卷第8期Lossoftheproapoptoticprotein,Bim,breaksBcellanergy
1HowardHughesMedicalInstituteandIntegratedDepartmentofImmunology,NationalJewishMedicalandResearchCenter,2DepartmentofImmunology,3DepartmentofMedicine,4DepartmentofPharmacology,and5DepartmentofBiochemistryandMolecularGenetics,UniversityofColoradoHealthSciencesCenter,Denver,CO80206AlthoughBcellsthatre...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第3期丙型肝炎病毒包膜蛋白E2人源單鏈可變區抗體的篩選與鑑定
1材料和方法 1.1材料HCVE2抗原購於美國Virostat公司,系基因工程有達純化的重組蛋白。人源化噬菌體抗體文庫爲輕鏈可變區和重鏈可變區經甘氨酸接頭(Gly4Ser)3連接的抗體文庫。輔助噬菌體M13K07購於Pharmacia公司,Wizard質...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學AssociationbetweenRespiratoryDiseaseandBacterialandViralInfectionsinBritishRacehorses
AnimalHealthTrust,LanwadesPark,Kentford,Newmarket,Suffolk,UnitedKingdomABSTRACTRespiratorydiseaseisimportantinhorses,particularlyinyoungThoroughbredracehorses,andinflammationthatisdetectedinthetracheaandbronchi(termedinflammatoryairwaydisease[IAD])ismoresignificantinthispopulationintermsofimpactandf...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第1期SelectivedysregulationoftheFcIIBreceptoronmemoryBcellsinSLE
1DepartmentofMedicine,ColumbiaUniversityMedicalCenter,NewYork,NY100322DepartmentofMedicine,AlbertEinsteinCollegeofMedicine,Bronx,NY104613MacroGenicsInc.,Rockville,MD208504TheRockefellerUniversity,NewYork,NY10021TheinappropriateexpansionandactivationofautoreactivememoryBcellsandplasmablastscontribute...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第9期SequenceAnalysisofthemsp4GeneofAnaplasmaphagocytophilumStrains
DepartmentofVeterinaryPathobiology,CollegeofVeterinaryMedicine,OklahomaStateUniversity,Stillwater,OklahomaDivisionofViralandRickettsialDiseases,CentersforDiseaseControlandPrevention,Atlanta,GeorgiaDiagnosticImmunologyLaboratory,WadsworthCenterWadsworthCenterforLaboratoriesandResearch,NewYorkStateDep...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第3期