DistinctSignalingProfilesof1and2AdrenergicReceptorLigandstowardAdenylylCyclaseandMitogen-ActivatedProteinKinaseRevealsthePluridimensionalit
...ssuggestthatefficacymayalsobeinfluencedbythesignalingeffectorsengagedbyauniquereceptor.Todirectlyandsystematicallytestthispossibility,weassessedtheabilityofapanelof-adrenergicligandstomodulatetheactivityoftwoeffectorsystems,theadenylylcyclase(AC)andthemitogen-activatedproteinkinase(MAPK),via1and2adr...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第11期胃雙對比造影檢查診斷淺表型早期胃癌
...mach,payattentiontotheuseofmobilemethod,thatwillbepossibletoobtainhigh-qualitydouble-contrast-madefilms,toclearlyindicatethelesions,thentoraisediagnosislevelofthistypeofearlygastriccancer.[Keywords]doublecontraststudyofstomach;superficialtypeearlygastriccancer;X-raydiagnosis淺表型...
醫源資料庫;在線期刊;中華現代影像學雜誌;2009年第6卷第2期DECB對超聲乳化角膜內皮損傷修復的促進作用*
...sjustBSS.Differenttimeafteroperationobservedcorneal,cornealendotheliumwasquantitativeanalyzedthroughcornealendotheliumimagemicrographsystem.Thestructureofcornealendotheliumwasobservedbymicroscope.ResultsObservedthoughmicroscope,cellmorphouswerebetterintheexperimentgroupthanthatincontrolgroup.And...
醫源資料庫;在線期刊;中華現代耳鼻喉雜誌;2007年第4卷第1期Pathogenesisofpersistentlymphaticvesselhyperplasiainchronicairwayinflammation
...erantibiotictreatmentoftheinfection,inflammationandremodelingofbloodvesselsquicklysubsided,butlymphaticvesselspersisted.Together,thesefindingssuggestthatwhenlymphangiogenesisisimpaired,airwayinflammationmayleadtobronchiallymphedemaandexaggeratedairflowobstruction.Correctionofdefectivelymphangiogenes...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第2期Cyclooxygenase-2ExpressionandInhibitioninAtherothrombosis
...ionofCOX-2inthecellularplayersofatherothrombosis,itsroleasadeterminantofplaque“vulnerability,“andtheclinicalconsequencesofCOX-2inhibition.Recentstudiesfromourgroupsuggestthatvariableexpressionofupstreamanddownstreamenzymesintheprostanoidbiosyntheticcascademayrepresentimportantdeterminantsofthefu...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第2期AbnormalIntravoxelCerebralBloodFlowHeterogeneityinHumanIschemicStrokeDeterminedbyDynamicSusceptibilityContrastMagneticResonanceImaging
...eterthatcorrelatedwiththeclinicalscore.Conclusions—FHpredictsinfarctsizeequallywellwiththeotherperfusionparametersbutissuperiorincorrelationwiththeclinicalscore.FHcaneasilybeincorporatedtohyperacutestrokeimagingwithoutadditionalefforts.KeyWords:magneticresonanceimagingperfusionstrokeIntroductionRa...
醫源資料庫;在線期刊;中風學雜誌;2005年第36卷第1期寧夏回族青光眼眼血管血流動力學的研究
...18males.TheinstrumentweusedisTCDofthetypeMULTIGON500whichismadeinUSA.Thefrequencyofdetectingheadis2.0MHz.Thepowerofsupersoundis10percent,takingofsamplesisasingleblindmethodmadebyonlyonepersonwhocanpracticedusetheinstrument.Wedetectthearteriaophthalmica(OA)arteriacentralisretinaeandposteriorciliaryar...
醫源資料庫;在線期刊;中華現代耳鼻喉雜誌;2006年第3卷第1期寧夏回族青光眼眼血管血流動力學的研究
...18males.TheinstrumentweusedisTCDofthetypeMULTIGON500whichismadeinUSA.Thefrequencyofdetectingheadis2.0MHz.Thepowerofsupersoundis10percent,takingofsamplesisasingleblindmethodmadebyonlyonepersonwhocanpracticedusetheinstrument.Wedetectthearteriaophthalmica(OA)arteriacentralisretinaeandposteriorciliaryar...
醫源資料庫;在線期刊;中華現代眼科學雜誌;2006年第3卷第1期ProteinCLevelsAreRegulatedbyaQuantitativeTraitLocusonChromosome16
...eticmap.Variancecomponentlinkagemethodswereusedtoevaluatelinkageandtodetectquantitativetraitloci(QTL).Aregiononchromosome16(16q23),flankedbymarkersD16S3106andD16S516,showedstrongevidenceoflinkagewithPClevels(LOD=3.69).Thisregioncontains1positionalcandidategene,theNAD(P)H:dehydrogenasequinone1(NQO1),...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第7期ShortPolybasicPeptideSequencesArePotentInhibitorsofPC5/6andPC7:UseofPositionalScanning-SyntheticPeptideCombinatorialLibrariesasaToolfort
...CLs)arepowerfulmoleculartoolstoidentifyenzymesubstrateandpotentinhibitorysequencesandalsotoprovidecrucialinformationaboutactivesitedeterminants.PS-SPCLshavebeensurveyedforfurin,proproteinconvertase(PC)2,PC1/3,andPACE4andprovenefficienttoidentifypotentpeptidylinhibitorsinthelownanomolarrangeforfurina...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第1期