StatusofplasmafolateafterfolicacidfortificationofthefoodsupplyinpregnantAfricanAmericanwomenandtheinfluencesofdiet,smoking,andalcohol
...a.nih.gov.ABSTRACTBackground:AfricanAmericanwomenandsocioeconomicallychallengedwomenareatriskofcompromisedfolatestatusand,thus,offolate-relatedbirthdefects.DataarelimitedoncirculatingfolateconcentrationsinpregnantAfricanAmericanwomenafterfolicacidfortificationofthefoodsupplywasimplemented.Objective:...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2005年81卷第3期ComprehensiveTranscriptomeofProteasesandProteaseInhibitorsinVascularCells
...icaneurysms,oftenassociateswithinflammationandalteredgeneexpression,includingproteolyticenzymesthatplaymultipleandimportantrolesinextracellularmatrixdegradation,cellproliferationandmigration,andlatentenzymeorgrowthfactoractivation.MethodsandResults—Humansaphenousveinsmoothmusclecells,endothelialce...
醫源資料庫;在線期刊;中風學雜誌;2006年第37卷第2期高能聚焦超聲治療激素非依賴性前列腺癌
...果治療前後血清前列腺特異性抗原(PSA)值分別爲(42.5±20.2)ng/mL、(10.4±6.6)ng/mL;前列腺體積爲(45.2±12.5)mL、(3.5±1.1)mL;國際前列腺症狀評分爲19.5±5.5、8.5±4.5,治療前後比較具有顯著差異(P<0.05);治療併發症:輕度血尿2例。結論HIFU...
醫源資料庫;在線期刊;現代泌尿外科雜誌;2008年第12卷第5期羊水基質金屬蛋白酶與胎膜破裂的關係
...的活性(以37℃下每1ml羊水12h消化的明膠量表示,單位:ng/ml*12h),用加乙二胺四乙酸(終濃度80mmol/L)的羊水作陰性對照。(3)羊水中MMP成分的酶譜分析:參照Moll等[2]介紹的方法進行明膠電泳,電泳完畢將凝膠置於培養皿中,...
合作平臺;醫學論文;臨牀醫學與專科論文;婦產科學ProteinKinaseC(PKC)RegulatesOcularInflammationandApoptosisinEndotoxin-InducedUveitis(EIU)
...ofinterleukin-13onendotoxin-induceduveitisintheLewisratisdependentonsignalingactivityofproteinkinaseC(PKC).Tounderstandtheeffectofinterleukin-13orPKCinhibitortreatment,theactivationstatusofratbonemarrow-derivedmacrophageswasstudiedinvitro.At6hours,lipopolysaccharide-stimulatedmacrophagesproducedtumo...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第4期SubstancePNeurokinin1ReceptorActivationwithintheDorsalRapheNucleusControlsSerotoninReleaseintheMouseFrontalCortex
...Ponextracellular5-HTlevelsinthefrontalcortex,ventralhippocampus,andDRNbyusingintracerebralmicrodialysisinconsciousmice.IntrarapheSPinjectiondosedependentlydecreasedcortical5-HTrelease,whereasnoeffectsweredetectedintheventralhippocampus.CorticaleffectswereblockedbytheselectiveNK1receptorantagonistN-[...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第12期血管內皮生長因子水平與糖尿病患者微血管病變的觀察
...61(2000)05-0397-01Observationofvascularendothelialgrowthfactorandmicroangiopathyindiabetesmellitus 血管內皮生長因子(VEGF)是促進新生血管形成的主要細胞因子[1]。糖尿病視網膜病變是全身微血管病變的一部分,也是糖尿病患者重要的慢性...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學多腫瘤標誌物蛋白芯片系統(C12)對胃癌診斷的臨牀價值
...cerLIZhi-lin.DepartmentofSurgery,SecondTraditionalChineseMedicalHospital,YongzhouCity,HunanProvince425006,China【Abstract】ObjectiveToinvestigatetheapplicationofmulti-tumormarkersproteinchipdiagnosticsysteminthediagnosisofgastriccancer.MethodsOfthe70patientswithgastriccancer;60patientswhosufferedf...
醫源資料庫;在線期刊;中華中西醫雜誌;2007年第8卷第14期SyntheticRetinoidAm80ReducesScavengerReceptorExpressionandAtherosclerosisinMicebyInhibitingIL-
【摘要】Background-Macrophagescavengerreceptorsfacilitatetheuptakeofmodifiedlow-densitylipoprotein(LDL),formationoffoamcells,anddevelopmentofatherosclerosis.Giventhatproinflammatorycytokines,includingIL-6,canmodulatethemacrophagefoamingprocess,theaimofthepresentstudywastodeterminewhetherthesynth...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第5期cAMP-ResponseElement-BindingProteinMediatesTumorNecrosisFactor-–InducedVascularSmoothMuscleCellMigration
...oformationofvascularstenoticlesionssuchasatherosclerosisandrestenosisafterangioplasty.Previousstudieshavedemonstratedthattumornecrosisfactor-(TNF-)isapotentmigrationfactorforVSMCs.cAMP-responseelement-bindingprotein(CREB)isthestimulus-inducedtranscriptionfactorandactivatestranscriptionoftargetgeness...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2004年第24卷第9期