凝膠劑的臨牀應用研究進展
...,可用氫氧化鹼、胺類、氨溶液、碳酸氫鈉、硼砂、鹼性氨基酸類中和,中和後的水溶液在pH6~12時最爲粘稠,當pH12時,粘稠度下降,強電解質存在時粘度亦降低;暴露於陽光下迅速失去粘度,可加入抗氧劑使反應減慢。膠漿易...
醫源資料庫;在線期刊;中華醫學實踐雜誌;2010年第9卷第4期ImpairedProgressionofCerebralAneurysmsinInterleukin-1–DeficientMice
...doubutsu(KyotoJapan),and5-to6-week-oldIL-1gene–deficient(IL-1–/–)mice15andage-matchedcontrolB10mice(wild-type)werepurchasedfromTaconic(Hudson,NY).CerebralaneurysmswereinducedusingtheprocedurereportedbyMorimotoetal.6Theleftcommoncarotidarteryandposteriorbranchoftheleftrenalarterywereligatedwith...
醫源資料庫;在線期刊;中風學雜誌;2006年第37卷第3期HeparanSulfateRegulatestheAntiangiogenicActivityofEndothelialMonocyte-ActivatingPolypeptide-IIatAcidicpH
...nylidenedifluoridemembrane,andblockedwith5%skimmilkinTBST(10mMTris,pH7.5,0.15MNaCl,and0.1%Tween)for1h.PrecipitationofHSandEMAPIIwasconfirmedbyprobingwithanti-syndecan-1antibody(SantaCruzBiotechnology,Inc.)andanti-His-tagantibody(QIAGEN,Valencia,CA)intheTBSTcontaining0.1%skimmilk,respectively.Forthec...
醫源資料庫;在線期刊;分子藥理學雜誌;2005年第67卷第5期HCV核心區基因的截短及其表達
...的序列測定測序結果表明pGEX-TP11中目的基因除了第68位氨基酸殘基密碼子由GCG(丙氨酸)突變爲GCA(丙氨酸)爲同義突變之外,其餘序列與模板相同。25重組融合蛋白的誘導表達將經鑑定過的表達質粒pGEX-TP11,轉化感受態BL21...
醫源資料庫;在線期刊;中華醫藥雜誌;2006年第6卷第11期E-選擇素A561C基因多態性對高血壓的影響
...進行DNA多態性分析,電泳判斷基因型並測序。結果檢測到AA、AC、CC三種基因型。在高血壓病組與對照組之間基因型構成比差異有統計學意義。在高血壓病組AC-CC基因型和C等位基因頻率(6.92%和4.76%)顯著高於對照組(分別爲3.17%,2.22%)...
行業資訊;臨牀快報;遺傳與基因組Arachidonicacidstatusduringpregnancyisassociatedwithpolychlorinatedbiphenylexposure
...(2,3).SerumAAconcentrationsareusuallymaintainedevenathighseafoodintakes(4150;6),butanincreasedsupplyofeicosapentaenoicacid(EPA;20:5n-3)duringdevelopmentisthoughttoreduceAAconcentrations(7,8).Sometypesofseafoodmaycontaintoxiccontaminants,suchaspolychlorinatedbiphenyls(PCBs)(9)thatareknowntocausedev...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2003年77卷第3期上海藥物所用馬兜鈴酸誘發腎臟毒性機制有新發現
馬兜鈴酸(AA)是馬兜鈴酸腎病(aristolochicacidnephropathy,AAN)的致病原因,最新研究顯示它也可能是巴爾幹地方性腎病(Balkanendemicnephropathy,BEN)的致病原因,已經引起了國際上的高度重視,但其導致腎毒性的機理並不清楚。上海藥物所安...
行業資訊;臨牀快報;藥理學Ironbioavailabilityfrommaizeandbeans:acomparisonofhumanmeasurementswithCaco-2cellandalgorithmpredictions
...eanmeals.Theresultswereunaffectedbythevarietyofeithermaizeorbeans.AddingAA(15–20molarratiosofAA:iron)roughlytripledtheironabsorption(P0.0001)fromalltestmeals.AlthoughtheCaco-2modelpredictedaslightlyimprovedbioavailabilityofironfromACRmaizethanfromTZBmaize(P0.05),itaccuratelypredictedrelativeir...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年86卷第2期Docosahexaenoicandarachidonicacidconcentrationsinhumanbreastmilkworldwide
...ration,Columbia,MD(LMA)2RGJisdeceased.3BVwassupportedbyNIHTrainingGrantDK07158.4AddressreprintrequeststoJTBrenna,SavageHall,CornellUniversity,Ithaca,NY14850.E-mail:jtb4{at}cornell.edu.ABSTRACTConcentrationsofthelong-chainpolyunsaturatedfattyacids(LCPUFAs)docosahexaenoicacid(DHA,22:6n150;3)andarach...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年85卷第6期ModulationoftheCa2PermeableCationChannelTRPV4byCytochromeP450EpoxygenasesinVascularEndothelium
...ypelittermatesandexhibitprolongedwithdrawallatenciesduringacutetailheating.15Moreover,TRPV4canbeactivatedbyalargevarietyofchemicalstimuli,includinglowpHandcitrate11andthesyntheticphorbol-derivative4-phorbol12,13-didecanoate(4-PDD),whichcanbeconsideredthemostrobustanddirectchannelactivator.16Recently...
醫源資料庫;在線期刊;循環研究雜誌;2005年第95卷第10期