SurfaceResponseModelingtoExaminetheCombinationofAmphotericinBDeoxycholateand5-FluorocytosineforTreatmentofInvasiveCandidiasis
...hsomeofthecomplexissuessurroundingantifungalcombinationtreatmentcanbeaddressed.Invasivecandidiasis(INVC)isalife-threateningillness.Theattributablemortalityis38%49%[1,2],andtherateoftherapeuticfailureis20%50%[35];thesedataprovidethemajorimpetustocontinuallydevelopandrefinetreatmentstrategies.Thecombi...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第16期TidalVolumeReductioninPatientswithAcuteLungInjuryWhenPlateauPressuresAreNotHigh
...MV)approachusessmallertidalvolumes(VT)andlowerinspiratorypressuresthanwereusedinthepast(1–7).However,thereiscontroversyregardingtheextenttowhichVTandinspiratoryairwaypressuresshouldbereducedtoachievetheseobjectives(8–18).SomeinvestigatorshaverecommendedthatVTinpatientswithALI/ARDSshouldbereduced...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第11期Opticnervecompressionbynormalcarotidarteryinpatientswithnormaltensionglaucoma
...cdisccupping;magneticresonanceimagingTheterm,normaltensionglaucoma(NTG),isusedforpatientswithtypicalglaucomatousdamageoftheopticnerveheadandvisualfieldlossinspiteofnormalintraocularpressure(IOP).1,2VariousmechanismshavebeenproposedtoexplaintheoriginofNTG—forexample,vascularinsufficiency,decreasedo...
醫源資料庫;在線期刊;英國眼科學雜誌;2005年第89卷第2期DetectionofLungCancerbySensorArrayAnalysesofExhaledBreath
...n,Inc.,Pasadena,CaliforniaABSTRACTRationale:Electronicnosesaresuccessfullyusedincommercialapplications,includingdetectionandanalysisofvolatileorganiccompoundsinthefoodindustry.Objectives:Wehypothesizedthattheelectronicnosecouldidentifyanddiscriminatebetweenlungdiseases,especiallybronchogeniccarcinom...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第6期Bacterial-PopulationResponsestoDrug-SelectivePressure:ExaminationofGarenoxacin‘sEffectonPseudomonasaeruginosa
...eledbyuseof3parallelinhomogeneousdifferentialequations.Modelparameterswereusedtoderivetheminimal,orbreakpoint,drugexposurenecessarytosuppressamplificationoftheresistantsubpopulation.Inaprospective-validationstudy,wefoundthatadrugexposureneartobutbelowthecalculatedbreakpointamplifiedtheresistantsubpo...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第15期Morphologicalandfunctionalevidenceforanimportantroleoftheendothelialcellglycocalyxintheglomerularbarrier
...eandchargeselectivity.Inisoflurane-anesthetizedmice,Intralipiddropletswereusedasindirectmarkersoftheglomerularendothelialcell-surfacelayer,i.e.,theglycocalyx.ThemiceweregivenintravenousinjectionsofGAG-degradingenzymes,whichduetotheirhighmolecularweightremainedandactedintravascularly.Flow-arrestedkid...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第1期標準化病人在呼吸訓練實踐教學中的應用研究
...rdizedpatients,whilethetraditionalteachingwascarriedoutforthecontrolgroupcased.Thentheoperatingskillwerecomparedbetweentwogroupsandinvestigatestudentsinexperimentalgroupandstandardizedpatientsaswell.ResultsAstatisticalsignificancewasobtainedbetweentowgroupsinoperationscores.Studentsinexperimentalgro...
醫源資料庫;在線期刊;中華現代護理學雜誌;2012年第9卷第13期Effectofsupplementationwithcobalamincarriedeitherbyamilkproductoracapsuleinmildlycobalamin-deficientelderlyDutchpersons
...alth,whichneedstobemanagedadequately.Differentindicatorsandcutoffshavebeenusedtodefinemildcobalamindeficiency.Currently,plasmamethylmalonicacid(MMA)andhomocysteineconcentrationsareusedalongwithserumcobalaminconcentrationstoassesscobalamindeficiency.However,homocysteineisalsoelevatedinfolateandvitami...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2005年82卷第3期卵圓孔封堵材料(Amplatzer)對心功能的影響———組織多普勒研究
...oreandafterinterventionaltreatment.MethodsTissueDopplerimaging(TDI)wasusedtodetermineandcomparethemovementofmyocardialbeforeandafterinterventiontreatment.Diastolicvelocityandsystolicvelocityfromthemitralannulus,tricuspidannuˉlus,septalannulusandroofofatrialseptumwereobtainedintheapicalfour-...
合作平臺;在線期刊;中華實用醫藥雜誌;2004年第4卷第17期;論著憂慮康藥對動物抑鬱行爲和血漿cAMP、cGMP的影響及毒性試驗研究
...emodelratsintheopen-fieldtestandfluidcomsumptiontestweresignificantlydecreased,theplasmaconcentrationofcAMPwassignificantlyelevated;YouLvKangcanpartlyimprovethebehavioroftherats,theplasmaofcAMPweresignificantlydecreasedintheLiuWeiDiHuangWanandYouLvKanggroups.Themaximallytolerateddoseofmousewere360g/...
醫源資料庫;在線期刊;中華現代中醫學雜誌;2007年第3卷第4期