Hypoxia-InducedMediatorsofStem/ProgenitorCellTraffickingAreIncreasedinChildrenWithHemangioma
【摘要】Objective—Themechanismofneovascularizationduringtheproliferativephaseofinfantilehemangiomaispoorlyunderstood.Itisknownthatcirculatingbonemarrow-derivedendothelialprogenitorcells(EPCs)formnewbloodvesselsinischemictissuesusingmediatorsregulatedbythetranscriptionfactor,HIF-1.Mobilizat...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第12期TCR-BCR識別抗原機制在分子生態水平的比較
...-1,2(磷脂酶Cr-1,2)的磷酸化和活化,同時ras蛋白同Shc,Grb2和mSOS等組成活化複合體(activationcomplex),從而使Raf到達漿膜,起動絲/蘇氨酸激酶活化瀑布而引起細胞增殖,以適應提高免疫反應能力的需要。 傳統概念的...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學GinsenosideRe,aMainPhytosterolofPanaxginseng,ActivatesCardiacPotassiumChannelsviaaNongenomicPathwayofSexHormones
...tantibody(CellSignaling),followedbyincubationwitha1:40,000-dilutedhorseradishperoxidase-conjugatedanti-rabbitIgG(DakoJapanCo.Ltd.,Kyoto,Japan).Proteinsweredetectedusinganadvancedenhancedchemiluminescencesystem(GEHealthcare,LittleChalfont,Buckinghamshire,UK).Proteinconcentrationsweredeterminedusingth...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第12期甲磺酸培氟沙星
正式名:甲磺酸培氟沙星 漢語拼音:JiaHuangSuanPeiFuShaXing 標準號:WS-343(X-286)-94 拉丁文或英文:PEFLOXACINIMESYLAS 主要活性成分:本品爲1-乙基-6-氟-1,4-二氫-7-(4-甲基-1-哌嗪)-4-氧-3-喹啉羧酸甲基磺酸鹽。按乾燥...
藥品天地;專業藥學;藥品質量標準;西藥第八部分HematopoieticStemCellsProvideRepairFunctionsafterLaser-InducedBruch??sMembraneRuptureModelofChoroidalNeovascularization
...s(HSCs)iswell-appreciatedbecausethesecellsareknownfortheirplasticity.WehaveshownthatadultHSCsdifferentiateintoendothelialcellsandparticipateinbothretinalandchoroidalneovascularization.WeaskedwhetherHSCsparticipatedinthewoundingresponsebyformingastrocytes,retinalpigmentepithelia(RPE),macrophages,andp...
醫源資料庫;在線期刊;美國病理學雜誌;2006年第168卷第3期ImpairedhumoralimmunityinX-linkedlymphoproliferativediseaseisassociatedwithdefectiveIL-10productionbyCD4+Tcells
...ey,Sydney,NewSouthWales,Australia.3DivisionofPaediatricOncology,Children’sHospitalofPhiladelphia,Philadelphia,Pennsylvania,USA.4SanRaffaeleTelethonInstituteforGeneTherapy,Milan,Italy.5Vita-SaluteSanRaffaeleUniversity,Milan,Italy.6DepartmentofClinicalImmunology,RoyalPrinceAlfredHospital,Camperdown,...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第4期苯佐卡因藥物被指安全性存疑涉多家上市公司
...卡因的藥品批號至少有29個,生產廠商包括現代製藥(600420,SH)、雙鶴藥業(600062,SH)、白雲山A(000522,SZ)等。 上述三家上市公司所獲得的含苯佐卡因批號的藥品分別爲苯佐卡因含片(現代製藥)、氯己定苯佐卡因含片(北京萬輝雙鶴藥...
藥品天地;專業藥學;藥品不良反應海口市肺結核菌株耐藥性分析
...率以對RFP、INH、SM的耐藥率較高,耐多種藥率以對SR、HR、SHR、SRE、SHRE較高。結論本市檢出的肺結核分枝桿菌的耐藥情況嚴重,對結核病的預防、臨牀治療管理應引起高度的重視。【關鍵詞】肺結核;耐藥性;分枝桿菌 耐藥性肺...
醫源資料庫;在線期刊;中國熱帶醫學雜誌;2008年第8卷第10期TargetSolubleN-Ethylmaleimide-SensitiveFactorAttachmentProteinReceptors(t-SNAREs)DifferentlyRegulateActivationandInactivationGatingofKv2.2and
...iformlycontainbothsyntaxin1AandSNAP-25.However,usingimmunohistochemistry,weshowthatthedifferentpancreaticisletcellscontaindistinctdominantKvchannels,includingKv2.1incellsandKv2.2inandcells,whoseinteractionswiththeSNAREproteinswould,respectivelyregulateinsulin,glucagonandsomatostatinsecretion.Wethere...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第9期Superiorityofcombinationofthiazidewithangiotensin-convertingenzymeinhibitororAT1-receptorblockeroverthiazidealoneonrenoprotectioninL-NAME/SH
...renalandglomerulardynamiceffectsofcombiningthiazideandangiotensinantagonistshavenotbeenreported.Thepresentstudywasdesignedtoexaminetheeffectsofhydrochlorothiazide(HCTZ)aloneorincombinationwithanangiotensin-convertingenzymeinhibitororANGIItype1-receptorblockeronrenalhemodynamics,glomerulardynamics,re...
醫源資料庫;在線期刊;美國生理學雜誌;2005年第288卷第8期