IntragenicSuppressionofTrafficking-DefectiveKCNH2ChannelsAssociatedwithLongQTSyndrome
...tsofMedicine,PediatricsMolecularPharmacology,MayoClinicCollegeofMedicine,Rochester,Minnesota(D.J.T.,M.J.A.)AbstractMutationsintheKCNH2orhumanether-a-go-goeCrelatedgene-encodedK+channelreducefunctionalKCNH2current(IKCNH2)tocauselongQTsyndrome(LQT2)bymultiplemechanisms,includingdefectsinintracellulart...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第1期第二節 個別氨基酸代謝
...謝稱爲一碳單位代謝。 體內的一碳單位有:甲基(-CH3,methyl)、甲烯基(-CH2,methylene),甲炔基(-CH=,methenyl)、甲酰基(-CHO,formyl)及亞氨甲基(-CH=NH,formimino)等。它們可分別來自甘氨酸、組氨酸、絲氨酸、色氨酸、蛋氨酸等(...
醫源資料庫;醫源圖書館;教材類;生物化學與分子生物學TypingofNonencapsulatedHaemophilusStrainsbyRepetitive-ElementSequence-BasedPCRUsingIntergenicDyadSequences
...atypingmethod(IDS-PCR)fornonencapsulatedHaemophilusstrainsandcomparedthistechniquewithpulsed-fieldgelelectrophoresis(PFGE)ofDNArestrictedwithSmaI.IDS-PCRwasrapid,easytoperform,andreproducible,withahighdiscriminatorycapacityfornontypeableHaemophilusinfluenzae(NTHI)strains.The69NTHIstrainstestedgenera...
醫源資料庫;在線期刊;微生物臨牀雜誌;2003年第41卷第8期Parenteralnutritionresultsinimpairedlactosedigestionandhexoseabsorptionwhenenteralfeedingisinitiatedininfantpigs
DouglasGBurrin,BarbaraStoll,XiaoyanChang,JohannesBvanGoudoever,HisaoFujii,SusanMHutsonandPeterJReeds1FromtheUSDepartmentofAgriculture,AgriculturalResearchService,ChildrensNutritionResearchCenter,DepartmentofPediatrics,BaylorCollegeofMedicine,Houston(DGB,BS,XC,JBvG,andPJR),andtheDepartmentofBio...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2003年78卷第3期成人Still病併發急性心包填塞1例
...(adultonsetStilldisease,AOSD)是一種病因未明的以長期間歇性發熱、關節炎或關節痛、皮疹、肌痛、咽痛爲主要臨牀表現,並伴有中性粒細胞增多以及血小板增多,嚴重者可伴有系統損害。由於本病臨牀表現複雜,無特異的診斷方法...
醫源資料庫;在線期刊;中華現代臨牀醫學雜誌;2008年第6卷第2期ComparisonofEnzyme-LinkedImmunosorbentAssayImmunoblottingandPCRforDiagnosisofToxoplasmicChorioretinitis
...bourg,F-67091Strasbourg,France,3DepartmentofOphthalmology,UniversityofBern,CH-3010Bern,Switzerland2Received13March2003/Returnedformodification12May2003/Accepted24May2003 ABSTRACTTopAbstractIntroductionMaterialsandMethodsResultsDiscussionReferencesOculartoxoplasmosisisthemajorcauseofposterioruvetis...
醫源資料庫;在線期刊;微生物臨牀雜誌;2003年第41卷第8期高效液相色譜與化學發光分析聯用檢測葛根素
...相對發光強度呈線性關係,在C18反相鍵合相爲色譜柱,KH2PO4-CH3OH-H2O爲流動相的條件下,基線穩定,脈動小,且使葛根素能達到基線分離。基於此,建立起葛根素的HPLC-CL分析新方法。方法的線性範圍爲1.8~180μg·L-1;相關係數爲0.9995;檢出...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文安痛藤化學成分的研究
...M—H),TOFMSMS327.08m/z:327.08(M—H,11%),312.07(M—H—CH3,70%),234.06(M—H—CH3一C2H603,90%),192.04(M—H—CH3一C4H804,100%);IRvmaxcm-1:3389.96,3251.68(一OH),2951.87(一CH3),2892.28(一CH2一),1704.38(C=0),1612.27,1528.64...
藥品天地;專業藥學;實驗技術;色譜技術;色譜分析實例LipoproteinAnalysisWeek2:Electrophoresis
...ins.SDS-Polyacrylamidegelelectrophoresis:Electrophoresisistheprocessinwhichchargedparticlesmigratethroughasolidorliquidmatrixinresponsetoapplicationofanelectricfield.Rateofparticlemovementisproportionaltothecharge:massratiooftheparticleandtoitsfrictionalresistance.Largerparticlesmovemoreslowly,and...
藥品天地;專業藥學;實驗技術;生化實驗;脂肪實驗2,6-二氯嘌呤的高效液相色譜分析
...5epH7.0fwater圖32,6-二氯嘌呤在不同pH流動相中的色譜圖fig3thechromatogramof2,6-dichloropurineindifferentpHmobilephase 表一不同pH的流動相對2,6-二氯嘌呤分離的影響table1Theinfluencetoseparationof2,6-dichloropurineindifferentpHmobilephase保留時間(分)/pHreserved...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文