Povertyandobesity:theroleofenergydensityandenergycosts
...nNutritionResearchCenter,UniversityofCalifornia,Davis(SES)2AddressreprintrequeststoADrewnowski,NutritionalSciencesProgram,305RaittHall,Box353410,UniversityofWashington,Seattle,WA981953410.E-mail:adamdrew{at}u.washington.edu.ABSTRACTManyhealthdisparitiesintheUnitedStatesarelinkedtoinequalitiesi...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年79卷第1期AProteinToxinfromtheSeaAnemonePhyllodiscussemoniTargetstheKidneyandCausesaSevereRenalInjurywithPredominantGlomerularEndothelialDamage
...nandswellingthatoftentakesmonthstoresolve.2WerecentlyreportedamoreserioussequelaofenvenomationbyP.semoni;thevictimdevelopedunexplainedacuterenalfailurewithoutevidenceofdysfunctionofotherorgans.2Fromhospitalrecordscoveringthelast6yearsintheOkinawaarea,therewereatleastthreeothercaseswithacuterenalfail...
醫源資料庫;在線期刊;美國病理學雜誌;2007年第169卷第8期Postnatalacquisitionofendotoxintoleranceinintestinalepithelialcells
...talintestinalmacrophages,incontrast,wereconstitutivelynonresponsivetoLPS.AcquisitionofLPSresistancewasparalleledbyaspontaneousactivationofIECsshortlyafterbirthasillustratedbyphosphorylationofIB-andnucleartranslocationofNF-Bp65insituaswellastranscriptionalactivationofMIP-2.Importantly,thespontaneousI...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第4期Pathogenesisofpersistentlymphaticvesselhyperplasiainchronicairwayinflammation
...erantibiotictreatmentoftheinfection,inflammationandremodelingofbloodvesselsquicklysubsided,butlymphaticvesselspersisted.Together,thesefindingssuggestthatwhenlymphangiogenesisisimpaired,airwayinflammationmayleadtobronchiallymphedemaandexaggeratedairflowobstruction.Correctionofdefectivelymphangiogenes...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第2期最新國內最具影響力的學術論文(生物類)
...一篇文章:“Ahumangutmicrobialgenecatalogueestablishedbymetagenomicsequencing”入選,文章公佈了人體腸道菌基因組研究成果,這不僅將對人類自身健康與體內微生物的微妙關係做出科學的詮釋,也更有助於預防、監控和干預由腸道菌羣引發...
醫藥經濟;生物技術;技術要聞MolecularEpidemiologyofClinicalCryptococcusneoformansStrainsfromIndia
...diaInstituteforMolecularBioscienceandARCCentreinBioinformatics,UniversityofQueensland,Queensland,AustraliaABSTRACTLittleisknownaboutthemolecularepidemiologyofthehumanpathogenicfungusCryptococcusneoformansinIndia,acountrynowinthemidstofanepidemicofAIDS-relatedcryptococcosis.Westudied57clinicalisolate...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第11期MycobacteriumtuberculosisGrowthControlbyLungMacrophagesandCD8CellsfromPatientContacts
...sedinhouseholdsdevelopreactivationTBduringtheirlifetime(3)and50to75%donotacquireMtbinfectionasdeterminedbytuberculinskintesting(TST)(7,8).Byinference,itcanthusbeassumedthatthelocalalveolarenvironmentofHHCduringitsinitialinteractionwithMtbefficientlycontainsorabrogatestheinfectioninthemajorityofcases...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2006年第173卷第2期DiagnosticValueofMeasuringEpstein-BarrVirus(EBV)DNALoadandCarcinoma-SpecificViralmRNAinRelationtoAnti-EBVImmunoglobulinA(IgA)andIgGAntib
...CyclerPCR,85.9%ofpatientswerepositiveand60.4%hadlevelsabovetheCOV.ThisassayquantifiedasignificantlyhigherEBVloadthanthe213-bpPCRassay(P0.0001),suggestingthatcirculatingEBVDNAisfragmented.Usingdatafrom11differentstudies,weshowedasignificantinversecorrelationbetweenPCRampliconsizeandthepercentageofpat...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第7期Pathogenicroleforskinmacrophagesinamousemodelofkeratinocyte-inducedpsoriasis-likeskininflammation
...proliferative,inflammatoryskindiseaseinK14-Cre-IKK2fl/flmicewasadirectconsequenceofthepresenceofmacrophagesintheskin,astargeteddeletionofCD18,whichpreventedaccumulationofgranulocytesbutnotmacrophages,didnotleadtomajorchangesinthephenotype.TargeteddeletionofthereceptorforIFN-revealedthatthepathogenes...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第8期UptakeofLeishmaniamajorbydendriticcellsismediatedbyFcreceptorsandfacilitatesacquisitionofprotectiveimmunity
...,Tcells,andnoIL-12production.Herein,wedemonstratethatuptakeofL.majorbyDCsrequiredparasite-reactiveimmunoglobulin(Ig)GandinvolvedFcRIandFcRIII.Invivo,DCinfiltrationofL.major–infectedskinlesionscoincidedwiththeappearanceofantibodiesinsera.SkinofinfectedBcell–deficientmiceandFc–/–micecontainedf...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第1期