科學家預言千萬年後男性將滅絕都是基因的錯
...時,它的長度和擁有的基因數量,與X染色體相差無幾。然而,在億萬年的進化歷程中,由於環境的影響以及發育過程的失誤等原因,Y染色體上的許多基因,先後因突變成了失去功能的假基因,它們相繼不翼而飛了。與此同時,Y...
行業資訊;臨牀快報;遺傳與基因組TherapeuticPotentialofaSyntheticPeptideInhibitorofNuclearFactorofActivatedTCellsasAntirestenoticAgent
...lyinhibitedPDGF-BBandthrombin-inducedinterleukin-6,interleukin-8,transforminggrowthfactor-ß1,stromalcell-derivedfactor-1,andmonocytechemotacticprotein-1expressioninvSMCs.UnlikeFK506orCsA,VIVITdidnotaffectnuclearfactorBreportergeneactivationanddidonlymarginallyaffectendothelialwoundhealinginvit...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第7期比格犬血漿中託烷司瓊的HPLC法測定
...3%三乙胺,用冰醋酸調pH7.2;檢測波長283nm。線性範圍5.45~700ng/mL, 最低檢測濃度爲3.0ng/mL ,回收率爲79.9%~85.8%,日內RSD爲1.06%~4.27%,日間RSD爲2.94%~9.89%。採用本法對比格犬口服託烷司瓊的藥代動力學進行了研究。關鍵詞:託烷司瓊...
藥品天地;專業藥學;實驗技術;色譜技術;色譜論文HPLC法測定金地顆粒中綠原酸的含量
...方程:Y=(3.865×104)X-24569.6(r=0.9996)。最低檢測限量爲0.3ng。結論方法簡便可行,結果可靠。 關鍵詞綠原酸金地顆粒反相高效液相色譜法 金地顆粒由金銀花、生地等五味中藥組成,具有清熱解毒、滋陰潤燥的功效,安全...
合作平臺;在線期刊;中華現代中西醫雜誌;2005年第3卷第11期;醫學研究Levosimendanprotectsagainstexperimentalendotoxemicacuterenalfailure
...cionotropicandpossibleanti-inflammatoryproperties,mighthaveutilityincombatingthisformofARF.CD-1micewereinjectedwithLPS±LS.LSeffectsonLPS-inducedsystemicinflammation(plasmaTNF-/MCP-1;cardiorenalmRNAs),plasmaNOlevels,andazotemiawereassessed.BecauseKATPchannelopeninghasbeenreportedtomediatehypox...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第6期LowCirculatingEndogenousSecretoryReceptorforAGEsPredictsCardiovascularMortalityinPatientsWithEnd-StageRenalDisease
...hodsandResults-Thecohortwasfollowedforamedianof111months,and74deathsincluding34cardiovasculardeathswererecorded.PlasmaesRAGEwasmeasuredatbaseline.CumulativeincidenceofcardiovasculardeathbyKaplan-MeierestimationwassignificantlyhigherinsubjectsinthelowesttertileofplasmaesRAGEthanthoseinthemiddleortheh...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第1期Unbalancedserumleptinandghrelindynamicsprolongpostprandialsatietyandinhibithungerinhealthyelderly:anotherreasonforthe“anorexiaofaging“
...RACTBackground:Inhealthyelderly,areductionfromtheappetiteandfoodintakeofyoungeryearshasbeendefinedasthe“anorexiaofaging,“whichmaycausemalnutrition.Leptinandghrelinmayalterthecontrolofhungerandsatietyandthusleadtoanorexia.Objective:Theaimofthisstudywastoinvestigatehowagingaffectsserumleptinandghr...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2006年83卷第5期SpecificandSensitiveDetectionofNeisseriagonorrhoeaeinClinicalSpecimensbyReal-TimePCR
...icalMicrobiologyandInfectiousDiseases,GelreHospitals,LocationLukas,ApeldoornGGGD,MunicipalHealthService,AmsterdamLaboratoryforPathologyandMicrobiology,PAMM,Veldhoven,TheNetherlandsABSTRACTEarlydiagnosisofNeisseriagonorrhoeaeinfectionsisimportantwithregardtopatients‘healthandinfectivity.Wereportthe...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第11期Serumleptinconcentrationsandbodyadiposemeasuresinolderblackandwhiteadults
ConstanceERuhl,JamesEEverhart,JingzhongDing,BretHGoodpaster,AlkaMKanaya,EleanorMSimonsick,FrancesATylavskyandTamaraBHarrisfortheHealth,Aging,andBodyCompositionStudy1FromSocialandScientificSystems,Inc,SilverSpring,MD(CER);theNationalInstituteofDiabetesandDigestiveandKidneyDiseases,NationalInstituteso...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年80卷第3期ExpressionofCOX-2inplatelet-monocyteinteractionsoccursviacombinatorialregulationinvolvingadhesionandcytokinesignaling
...ity,Utah,USA.AbstractTightregulationofCOX-2expressionisakeyfeaturecontrollingeicosanoidproductioninatherosclerosisandotherinflammatorysyndromes.Adhesiveinteractionsbetweenplateletsandmonocytesoccurintheseconditionsanddeliverspecificsignalsthattriggerinflammatorygeneexpression.Usingacellularmodelofmo...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第10期