InfectionwithHIV-1InducesaDecreaseinmtDNA
...s-sectionalstudieshavesuggestedthatinfectionwithhumanimmunodeficiencyvirus(HIV)type1couldreducethemitochondrialDNA(mtDNA)contentofbloodcells.WeinvestigatedmtDNAcontentinperipheralbloodmononuclearcells(PBMCs)obtainedfrom36antiretroviraltherapynaivedocumentedHIV-1seroconverters,beforeandafterseroconve...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第9期GeorgeChurch專訪:CRISPR是如何引領基因編輯革命的?
...動物模型來治療人類癌症,或者是創造了血紅細胞來抵抗HIV病毒。CRISPR從發現到應用的歷程CRISPR基因組編程技術是近兩年興起的一種新技術,2013年兩篇Science新聞開創了CRISPR基因組編輯技術的新時代,隨後生命科學界颳起了CRISPR...
醫藥經濟;生物技術;技術要聞EffectofHIVInfectionandAntiretroviralTherapyonHepatitisBVirus(HBV)SpecificTCellResponsesinPatientsWhoHaveResolvedHBVInfection
CentreforSexualHealthandHIVResearch,InstituteofHepatologyDivisionofInfectionandImmunity,RoyalFreeandUniversityCollegeMedicalSchool,London,UnitedKingdomCoinfectionwithhepatitisBvirus(HBV)isacommonoccurrenceinhumanimmunodeficiencyvirus(HIV)positivepatientsandanincreasingcauseofmorbidityandmortality.Th...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第7期Useofserumretinol-bindingproteinforpredictionofvitaminAdeficiency:effectsofHIV-1infection,proteinmalnutrition,andtheacutephaseresponse
...raimwastodeterminewhetherRBPisagoodsurrogatemeasureforretinolinthecontextofHIV-1infection,proteinmalnutrition,andtheacutephaseresponse.Design:TherelationbetweenRBPandretinolwasexaminedinacross-sectionalstudyof600Kenyanwomen.Results:TherewasahighcorrelationbetweenconcentrationsofRBPandthoseofretinol(...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2004年79卷第2期Affordable,AbbreviatedRocheMonitorAssayforQuantificationofHumanImmunodeficiencyVirusType1RNAinPlasma
...itcanbereduced50%byusingonlythe1:1,1:25,and1:625humanimmunodeficiencyvirus(HIV)andthe1:1quantitationstandarddilutions.Thisabbreviatedtestappliedto1,774mostlyAfricansampleshadresultsnearlyidenticaltothoseobtainedfollowingthepackageinsertinstructions.Tomakethisapproachfeasible,Rochewouldhavetoprovidea...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第8期UpdateinTuberculosis2005
...95%CI,0.35–6.13).OnedrawbackofthestudywasthelackofinformationregardingtheHIVstatusforabouthalfofthepatients,buthavingunknownHIVstatuswasnotfoundtobeassociatedwithextrathoracictuberculosisinmultivariateanalysis.Thus,thefindingsofYangandcoworkerssuggestthattheplcDgeneofM.tuberculosismightbepotential...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2006年第173卷第5期DetectionandIdentificationofEnterocytozoonbieneusiandEncephalitozoonSpeciesinStoolandUrineSpecimensbyPCRandDifferentialHybridization
...iculihavebeendescribedasopportunisticpathogensinhumanimmunodeficiencyvirus(HIV)-infectedpatientsandotherimmunocompromisedpatientssuchastransplantrecipients(11,18,24,29,34,36).Infectionswithmicrosporidiainimmunocompetentindividualssuchastravelershavealsobeendescribed(31,35).InHIV-infectedpatients,E.b...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第2期傳染性軟疣
...而像小的皮角,稱爲角化性軟疣。一般無自覺症狀。感染HIV的病例,傳染性軟疣的發病率增加,而且軟疣廣泛播散和出現大的損害,有報道AIDS病人面部有巨大的軟疣,易與基底細胞上皮瘤混淆。此外,曾報道兩例廣泛的、急性...
求醫問藥;疾病手冊;皮膚性病科DeterminantsoflowbirthweightamongHIV-infectedpregnantwomeninTanzania
...eight(LBW)increasestheriskofinfantdeath,butlittleisknownaboutitscausesamongHIV-infectedpopulationsinsub-SaharanAfrica.Objective:Weassessedsociodemographic,nutritional,immunologic,parasitic,andinfantriskfactorsforbirthweight,LBW,andsmall-for-gestational-age(SGA)statusinacohortof822HIV-positivewomenen...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2001年74卷第6期PersistentNF-BactivationinrenalepithelialcellsinamousemodelofHIV-associatednephropathy
...niversitySchoolofMedicine,Cleveland,OhioABSTRACTHumanimmunodeficiencyvirus(HIV)-associatednephropathy(HIVAN)iscaused,inpart,bydirectinfectionofkidneyepithelialcellsbyHIV-1.Inthespectrumofpathogenichost-virusinteractions,abnormalactivationorsuppressionofhosttranscriptionfactorsiscommon.NF-Bisanecessa...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第2期