Differentialexoproteaseactivitiesconfertumor-specificserumpeptidomepatterns
...anceofthesesignaturesasvalidbiomarkersfordiseasemayfollowsequencecharacterizationofthecomponentsandelucidationofthemechanismsbywhichtheyaregenerated.Usingahighlyoptimizedpeptideextractionandmatrix-assistedlaserdesorption/ionization–time-of-flight(MALDI-TOF)MS–basedapproach,wenowshowthatalimiteds...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第1期三維超聲對胎兒脣裂的診斷價值分析
...色多普勒超聲診斷儀。三維容積探頭,探頭頻率3.3~5.8MHz,採集圖像時,首先用二維超聲檢查胎兒顏面部,觀察胎兒脣部形態,然後再切換三維容積採集框,爲使三維成像清晰,儘量避免探頭移動和囑咐孕婦不要動,爲了增加感...
醫源資料庫;在線期刊;中華醫學研究雜誌;2006年第6卷第8期AntiviralTcellresponses:phalanxormultiprongedattack
...,andgroupIIIwerepatientswithactivehCMVinfection.ThenumbersofepitopesrecognizedbyCD8+TcellsinElispotassays,usingdifferentpoolsoftestepitopes,weregreaterinthosepatientsthatcontrolledhCMVinfection:groupsIandII.Thisobservationheldtrueforbothpp65andIE-1CD8+Tcellresponses.GroupIIAhadgreaterIE-1–specific...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第12期Nonhumanprimatemodelsofasthma
...hmaNearly40yearsagoresearchersbegantouserhesusmonkeys(Macacamulatta)sensitizedtotheintestinalhelminthparasiteAscarissuumtostudyallergen-inducedimmediateasthmaticresponsesintheairways(6).AmajorityofprimatescaughtinthewilddemonstrateskintestsensitivitytosolubleextractsofAscaris(12),presumablyfromprior...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第12期C-ReactiveProteinasaPredictorofIncidentIschemicStrokeAmongPatientsWithPreexistingCardiovascularDisease
...rchInstitute(M.B.,U.G.,S.B.),andCardiacRehabilitationInstitute(A.T.,Y.A.,E.Z.F.),ShebaMedicalCenter,TelHashomerCardiologyDepartment,RabinMedicalCenter,PetachTikva(M.H.)ChemistryLaboratory,WolsfonMedicalCenter,Holon(Z.M.,R.Z.)SacklerFacultyofMedicine,TelAvivUniversity,TelAviv(D.T.,M.B.,U.G.,M.H.,Z.M....
醫源資料庫;在線期刊;中風學雜誌;2006年第37卷第7期手術治療胰外瘻3例
...。 1臨牀資料 例1,患者男,36歲,主因重症急性胰腺炎術後胰瘻一年餘入院,患者一年餘前因重症急性胰腺炎在外院行剖腹探查:胰腺壞死組織清除並胰周引流術,術後抗炎、抑酸、抑酶、補液等對症治療,術後患者恢...
醫源資料庫;在線期刊;中華現代外科學雜誌;2010年第7卷第1期ReductionofCaspase-8and-9CleavageIsAssociatedWithIncreasedc-FLIPandIncreasedBindingofApaf-1andHsp70AfterNeonatalHypoxic/IschemicInjuryin
...pkinsUniversity,SchoolofMedicine,Baltimore,MdDepartmentsofNeurology(R.A.S.,Z.S.V.,D.M.F.)andPediatrics(R.A.S.,Z.S.V.,D.M.F.),UniversityofCaliforniaatSanFrancisco.AbstractBackgroundandPurpose—Caspase-8andcaspase-9areessentialproteasesoftheextrinsicandintrinsicapoptoticpathways,respectively.Weinvest...
醫源資料庫;在線期刊;中風學雜誌;2006年第37卷第2期SynergybetweenaplasminogencascadeandMMP-9inautoimmunedisease
...juryinautoimmuneandinflammatorydiseases.WedemonstratethataPlgcascadesynergizeswithMMP-9/gelatinaseBinvivoduringdermal-epidermalseparationinanexperimentalmodelofbullouspemphigoid(BP),anautoimmunedisease.BPwasinducedinmicebyantibodiestothehemidesmosomalantigenBP180.MicedeficientinMMP-9wereresistanttoe...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第4期Low-doseirradiationpromotestissuerevascularizationthroughVEGFreleasefrommastcellsandMMP-9–mediatedprogenitorcellmobilization
...cansecreteangiogenicfactorssuchasvascularendothelialgrowthfactor(VEGF).Ionizingirradiationhasalsobeenshowntohaveangiogenicpotentialinmalignantandnonmalignantdiseases.Weobservedthatlow-doseirradiationfostersmastcell–dependentvascularregenerationinalimbischemiamodel.IrradiationpromotedVEGFproduction...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第6期EvaluationofanUltrasensitivep24AntigenAssayasaPotentialAlternativetoHumanImmunodeficiencyVirusType1RNAViralLoadAssayinResource-LimitedS
...hapelHill,NorthCarolinaUniversityofGenoa,Genoa,ItalyABSTRACTAninexpensiveenzyme-linkedimmunosorbentassaymethodforhumanimmunodeficiencyvirustype1quantitation,ultrasensitivep24antigenassay(Up24),wascomparedwithRNAviralloadassay(VL).Up24had100%sensitivityofdetectionataviralloadof30,000,withsensitivityo...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第1期