Mappingquantitativetraitlociinhumans:achievementsandlimitations
HumanGeneticsUnit,IndianStatisticalInstitute,Kolkata,IndiaAbstractRecentadvancesinstatisticalmethodsandgenomictechnologieshaveusheredinanewerainmappingclinicallyimportantquantitativetraits.However,manyrefinementsandnovelstatisticalapproachesarerequiredtoenablegreatersuccessesinthismapping.Thepossibl...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第6期NOmediatesmuralcellrecruitmentandvesselmorphogenesisinmurinemelanomasandtissue-engineeredbloodvessels
1EdwinL.SteeleLaboratory,DepartmentofRadiationOncology,and2CardiovascularResearchCenter,DepartmentofMedicine,MassachusettsGeneralHospitalandHarvardMedicalSchool,Boston,Massachusetts,USA.3DepartmentsofPhysiologyandBioengineering,UniversityofPennsylvaniaSchoolofMedicine,Philadelphia,Pennsylvania,USA.A...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第7期後磨牙樁核修復技術的實驗研究
...n,WANGWei,DONGE-liang,etal. NationalLaboratoryofMEMSMicroelectronicsCenter,SoutheastUniversity,Nanjing210096,China 【Abstract】ObjectiveInthestomatologyregions,theclinicalapplicationofpost-corerestoringteethisincreasing.Yet,surprisingly,thecorrelativetheorya...
醫源資料庫;在線期刊;中華醫學研究雜誌;2005年第5卷第12期代謝性酸中毒
...是代償是有限度的,如果超過了機體所能代償的程度,酸中毒將進一步加劇。代謝性酸中毒是最常見的一種酸鹼平衡紊亂,以原發性HCO3-降低(<21mmol/L)和PH值降低(<7.35)爲特徵。【診斷】根據病人有嚴重腹瀉、腸瘻或輸尿...
求醫問藥;疾病手冊;普通外科急性冠脈綜合徵評估及危險分層
...及研究進展、不穩定型心絞痛和非ST段抬高心肌梗死的TIMI風險評分、使用多重生物標誌的風險分層(troponin,BNP,HbA1c,CRP,andCD40L等)。AcuteCoronarySyndromesEvaluationandRiskStratificationNewTerminologyinACSACS,acutecoronarysyndrome;MI,myocardialinfarction;UA,uns...
醫源資料庫;醫學文檔庫;心血管相關LowPlasmaRANTESLevelsAreanIndependentPredictorofCardiacMortalityinPatientsReferredforCoronaryAngiography
...】Objective-OurobjectivewastoevaluatetheprognosticvalueofbaselineplasmaRANTESlevelsinpatientswithknownorsuspectedcoronaryarterydisease.RANTESisachemokineproducedbyavarietyofcelltypesincludingplateletsthathasbeenimplicatedinatherosclerosis.MethodsandResults-BaselineplasmaRANTESlevelsweremeasuredin38...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第4期Carotenoidsandcardiovascularhealth
SariVoutilainen,TarjaNurmi,JaakkoMursuandTiinaHRissanen1FromtheResearchInstituteofPublicHealthandDepartmentofPublicHealthandGeneralPractice,UniversityofKuopio,Kuopio,Finland2SupportedbytheAcademyofFinland(grants201688and80185toSV),theJuhoVainioFoundation(grantstoSVandJM),andtheFinnishHeartResearchFo...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2006年83卷第6期ConstitutiveHedgehogSignalinginChondrosarcomaUp-RegulatesTumorCellProliferation
【摘要】Chondrosarcomaisamalignantcartilagetumorthatmayarisefrombenignprecursorlesions,suchasenchondromas.SomecasesofmultipleenchondromasarecausedbyamutationthatresultsinconstitutiveactivationofHedgehog-mediatedsignaling.WefoundthatchondrosarcomasexpressedhighlevelsoftheHedgehogtargetgenesPTCH1a...
醫源資料庫;在線期刊;美國病理學雜誌;2006年第168卷第1期RegulationofrenalNaPi-2expressionandtubularphosphatereabsorptionbygrowthhormoneinthejuvenilerat
【摘要】Growthhormone(GH)isanimportantfactorinthedevelopmentaladaptationtoenhancePireabsorption;however,thenephronsitesandmechanismsbywhichGHregulatesrenalPiuptakeremainunclearandarethefocusofthepresentstudy.Micropunctureexperimentswereperformedafteracutethyroparathyroidectomyinthepresenceandabs...
醫源資料庫;在線期刊;美國生理學雜誌;2004年第287卷第7期第三節 近親婚配
...(averageinbreedingcoefficient,a)。a值可按下列公式求出:a=Σ(Mi/N)(Ⅰi) Mi=某一類型近親婚配數;N=總婚配數,Ⅰi=某一類型近親婚配的近交係數。知道a值就可比較不同羣體中近親婚配的嚴重程度。一般來說,a值達1%左右已相...
醫源資料庫;醫源圖書館;教材類;醫學遺傳學基礎