Postprandialmetabolicutilizationofwheatproteininhumans
...itutetheprimaryproteinandenergysupplyinmostdevelopingcountries.Cerealsalsomakeasignificantcontribution(ofnearly20%)tothedailyproteinintakeindevelopedcountries,mainlyintheformofbread,pasta,rice,andbreakfastcereals(1).Wheatcontainsmoderateamountsofprotein(812%onaweightbasis)mainlycomposedofstora...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2005年81卷第1期NK細胞研究的幾個熱點問題
...化,細胞免疫治療的基礎與臨牀研究掀起新高潮,其中LAK細胞,ATL細胞,CIK細胞,CD3-AK細胞等各種經生物因子活化並擴增的效應細胞走上學術舞臺。NK細胞的研究者們不但從中獲得了更多的技術上的儲備(NK細胞純化,擴增,鑑定)...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學InvolvementofRhoKinaseinEndothelialBarrierMaintenance
【摘要】Objective—Rhokinasemediatesvascularleakagecausedbymanyvasoactiveagentsincludingthrombin.EnhancedRhokinaseactivityinducesendothelialbarrierdysfunctionbyacontractilemechanismviainactivationofMyosinPhosphatase(MP).Here,weinvestigatedthecontributionofbasalRhokinaseactivitytotheregulati...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2007年第27卷第11期SimultaneousDetectionofHepatitisCVirus(HCV)CoreAntigenandAnti-HCVAntibodiesImprovestheEarlyDetectionofHCVInfection
...inedusingthetwoavailableassaysforHCVAg(HCVcoreAgEIAbloodscreeningassayandtrak-Cassay)andHCVRNA.TheoverallobjectivewastodetermineifthisnewtestcouldconstituteanalternativetoNATforthediagnosisofHCVinfectionduringthewindowperiodandwhetherthesensitivityforantibodydetectionispreserved.MATERIALSANDMETHODSP...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第8期IL-1receptor–associatedkinaseMisacentralregulatorofosteoclastdifferentiationandactivation
...mple,toosteoporosis.Interleukin(IL)-1receptor(IL-1R)–associatedkinaseM(IRAK-M)isonlyexpressedincellsofthemyeloidlineageanditinhibitssignalingdownstreamofIL-1RandToll-likereceptors(TLRs).However,itlacksafunctionalcatalyticsiteand,thus,cannotfunctionasakinase.IRAK-Massociateswith,andpreventsthedisso...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第7期VascularNeointimalFormationandSignalingPathwayActivationinResponsetoStentInjuryinInsulin-ResistantandDiabeticAnimals
...erstenting,withuptoa98%increaseinp-ERK(anti-phosphoERK)anda54%reductioninp-Akt(anti-phosphoAkt)stainedcells.WesternblottingconfirmedaprofoundeffectofinsulinresistanceanddiabetesonAktandERKsignalinginstentedsegments.p-ERK/p-Aktratioinstentedsegmentsuniquelycorrelatedwithneointimalresponse(R2=0.888,P=...
醫源資料庫;在線期刊;循環研究雜誌;2005年第95卷第9期CD38isrequiredforprimingbyTNF-:amechanismforextracellularcoordinationofcellfate
...dtwice.CellularHDACassay.HDACactivitywasmeasuredbyusingtheFlurdeLysHDACkit(AK-500fromBiomol,PlymouthMeeting,PA).Briefly,equalnumbersofwild-typeandCD38-/-cellsweregrowninquadruplicate,andcellsweretreatedwith40ng/mlTNF-orcontrolfor12hbeforetheadditionoftheHDACsubstrate.At0,2,and4hafteradditionofthesub...
醫源資料庫;在線期刊;美國生理學雜誌;2007年第290卷第4期Enzyme-linkedImmunospotandTuberculinSkinTestingtoDetectLatentTuberculosisInfection
...G-vaccinatedindividualswithalowlikelihoodofLTBI.Inaschooltuberculosisoutbreak,ELISPOTresultscorrelatedsignificantlybetterthantuberculinskintestresultswiththedegreeofexposuretotheindexcase(12),suggestingthattheELISPOTisabettermarkerofLTBIthanthetuberculinskintest.However,thesensitivityofthetuberculin...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第11期StatusofplasmafolateafterfolicacidfortificationofthefoodsupplyinpregnantAfricanAmericanwomenandtheinfluencesofdiet,smoking,andalcohol
...enatalclinicwereassessed.At24wkofgestation,bloodsamplesandfood-frequencyintakedatawerecollected.Plasma5-MTHFAconcentrationsweredeterminedbyliquidchromatographymassspectrometryfor116subjectsandexaminedinacorrelationalstudydesign.Results:Dietaryfolateandmarkersofalcoholconsumptionwerepositivelya...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2005年81卷第3期DiscriminationwithinPhenotypicallyCloselyRelatedDefinitiveTypesofSalmonellaentericaSerovarTyphimuriumbytheMultipleAmplificationofPhageLocus
...noobservedreactionwithphageA21.Furthermore,therearecaseswherethereareveryweakreactionswithphagesA27andA35.Perceivedproblemswithphagetypingarefurthercompounded,asasignificantnumberofisolatescanbeuntypablebythismethod.Often,onephagetypemaypredominateinageographicalarea,makingdiscriminationbetweenoutbr...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第4期