HypoxiaIncreasesLDLOxidationandExpressionof15-Lipoxygenase-2inHumanMacrophages

...lyhigherextentthannormoxiccells.Interestingly,themRNAandproteinexpressionof15-lipoxygenase-2(15-LOX-2)aswellastheactivityofthisenzymeareelevatedinmacrophagesincubatedathypoxia.Boththeunspliced15-LOX-2andthesplicedvariant15-LOX-2sv-aarefoundinmacrophages.Inaddition,15-LOX-2wasidentifiedincarotidplaqu...

TheEffectsofLeukocyte-Type12/15-LipoxygenaseonId3-MediatedVascularSmoothMuscleCellGrowth

...394,Charlottesville,VA22908.E-mailcam8c@virginia.eduAbstractObjective—12/15-Lipoxygenase(12/15-LO)hasbeenimplicatedinthepathogenesisofvasculardisease.Vascularsmoothmusclecell(VSMC)proliferationisakeycomponentoftheresponsetoinjuryinvasculardisease.Theroleof12/15-LOinregulatingVSMCproliferationispoo...

感　冒

...10g　正北辛5g　蘇子12g　陳皮10g　枳殼10g　前胡10g　葛根15g　法夏10g　木香10g　雲苓10g　桔梗10g　白蔻5g　竹茹15g　甘草6g　生薑5片桔梗15g　枳殼10g　紫蘇10g　荊芥10g　木通15g　紫菀10g　黃芩15g　麻絨5g　川貝10g　寸冬10g　白蔻10g...

驗方五則

...症方：熟地25克，肉蓯蓉25克，骨碎補(制)40克，狗脊(制)15克，焦杜仲15克，菟絲子(鹽制)15克，萊菔子(炒)15克，川斷20克，制首烏(可用至20克)15克，桑寄生(炒)15克，懷牛膝15克，金櫻子(蜜炙)10～15克，雞血藤50克，淫羊藿(油炙)20克...

孔少華治療風溫感冒醫案

...弦滑而數，宜以清解。生石膏30g（先煎）杏仁泥10g板藍根15g生知柏各10g大青葉10g全蟬衣10g雙花10g青連翹10g霜桑葉10g杭菊花10g滑石塊15g橘絡20g條黃芩10g全瓜蔞30g葦根15g叄劑[按]內熱外感，孔老常以桑菊銀翹白虎和方加減，咽痛者，...

TheTransformingGrowthFactor-SuperfamilyMemberGrowth-DifferentiationFactor-15ProtectstheHeartFromIschemia/ReperfusionInjury

...omtheWomen’sHealthStudyshowthatserumlevelsofgrowth-differentiationfactor-15(GDF-15),adistantmemberofthetransforminggrowthfactor-superfamily,areanindependentriskindicatorforadversecardiovascularevents.However,thecellularsources,upstreamregulators,andfunctionaleffectsofGDF-15inthecardiovascularsyste...

GDF15/MIC-1FunctionsAsaProtectiveandAntihypertrophicFactorReleasedFromtheMyocardiuminAssociationWithSMADProteinActivation

...Wales,Sydney,Australia.AbstractHereweidentifiedgrowth-differentiationfactor15(GDF15)(alsoknownasMIC-1),asecretedmemberofthetransforminggrowthfactor(TGF)-superfamily,asanovelantihypertrophicregulatoryfactorintheheart.GDF15isnotexpressedinthenormaladultheartbutisinducedinresponsetoconditionsthatpromot...

四物湯加減治痛經的臨牀體會

...。如疼痛不移，氣滯血瘀痛經、加理氣化痰止痛藥．桃紅15g、紅花lOg，枳殼15g、元胡15g、五靈脂15g、丹皮15g、烏藥15g、香附子15g、虎枝15g、甘草1g，如經期數日小腹冷痛得熱痛減，按之痛甚經量少、經色黯黑有塊，寒溼凝滯痛經...

中藥治療痹症

...佐以補血活血。　　方藥：防風湯加減。防風20克，麻黃15克，葛根15克，肉桂15克，當歸15克，秦艽15克，甘草10克，生薑5片，大棗10克。上肢疼痛爲主加羌活15克，威靈仙15克，薑黃15克，川芎15克，桑枝15克，海風藤30克；下肢疼...

IL-15inducesCD4+effectormemoryTcellproductionandtissueemigrationinnonhumanprimates

...plicationiscontrolledbyantiretroviraltherapy(ART).Here,wedemonstratethatIL-15dramaticallyincreasesinvivoproliferationofrhesusmacaque(RM)CD4+andCD8+TEMcellswithlittleeffectonthenaiveorcentralmemoryT(TCM)cellsubsets,aresponsepatternthatisquitedistinctfromthatofeitherIL-2orIL-7.TEMcellsproducedinrespon...