骨髓基質幹細胞與受損PC12細胞的共育體系減少PC12的凋亡
...(瀋陽)爲了建立體外骨髓基質幹細胞(MSCs)與Aβ1-40損傷PC12的共育體系,探討共育體系抑制Aβ1-40致PC12凋亡的效應與可能機制。研究者分別培養MSCs與PC12,以Aβ1-40刺激PC12後,用轉移篩網轉移PC12。實驗分A組:正常培養的PC12+MSCs共育...
行業資訊;臨牀快報;神經科哮證分期治療
... 治宜溫肺散寒、祛痰平喘,方用射干麻黃湯加減:射干12克,麻黃6克,款冬花12克,紫菀12克,細辛6克,五味子9克,半夏12克(打碎),大棗4枚,生薑3片。痰多者再加白芥子和橘紅溫肺化痰;痰少喘甚者加白芥子、萊菔子和...
中醫中藥;中醫臨牀;臨牀討論DivergentrolesofIL-23andIL-12inhostdefenseagainstKlebsiellapneumoniae
...lCareMedicine,LouisianaStateUniversityHealthSciencesCenter,NewOrleans,LA701122AlcoholResearchCenter,LouisianaStateUniversityHealthSciencesCenter,NewOrleans,LA701123DepartmentofPhysiology,LouisianaStateUniversityHealthSciencesCenter,NewOrleans,LA701124UniversityofPittsburgh,Children‘sHospitalofPitt...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第6期IL-12基因轉染的人樹突狀細胞加強細胞免疫反應的體外研究
IL-12基因轉染的人樹突狀細胞加強細胞免疫反應的體外研究中國免疫學雜誌2000年第12期第16卷分子與細胞免疫學作者:曲春楓 顧培娣 鞠吉雨 孫宗棠單位:曲春楓鞠吉雨(山東濰坊醫學院免疫學教研室,濰坊261042);顧培娣...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學MethylationofestrogenreceptorandmutLhomolog1innormalcolonicmucosa:associationwithfolateandvitaminB-12statusinsubjectswithandwithoutco
...nthecolon.Objective:WetestedthehypothesisthatbiomarkersoffolateandvitaminB-12statusareassociatedwithestrogenreceptor(ER)andmutLhomolog1(MLH1)promotermethylationinsubjectswithandwithoutneoplasia.Design:Biopsiesofnormal-appearingcolorectalmucosafrom156subjectswithandwithoutcolorectalneoplasia(diseasef...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年86卷第4期急性腦梗死患者血清葉酸、VitB12水平及其臨牀意義
【摘要】目的探討急性腦梗死患者血清葉酸、VitB12水平及其臨牀意義。方法對88例首次發病的急性缺血性腦中風患者分爲兩個亞組,動脈硬化性腦梗死組32例,腔隙性腦梗死組56例,並設對照組35例,入院後用羅氏公司Elecsys2010型...
資料庫;在線期刊;中華現代內科學雜誌;2005年第2卷第7期AtypeIinterferonautocrine–paracrineloopisinvolvedinToll-likereceptor-inducedinterleukin-12p70secretionbydendriticcells
...niversity,Montreal,QuebecH3T1E2,CanadaDendriticcells(DC)produceinterleukin-12(IL-12)inresponsetoToll-likereceptor(TLR)activation.TwomajorTLRsignalingpathwaysparticipateintheresponsetopathogens:thenuclearfactor-B(NF-B)–dependentpathwayleadingtoinflammatorycytokinesecretionincludingIL-12andtheinterf...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第9期Folicacidfortification:thegood,thebad,andthepuzzleofvitaminB-
...rproductsintheUnitedStatesbefortifiedwithfolicacid(pteroylglutamicacid)R12;asubstanceformingonlyaveryminorcomponentofthefolatesinunfortifiedfood(2).Theargumentthenwasthatrandomizedclinicaltrialshadproventhatfolicacidtakeninveryearlypregnancycanmarkedlyreducetheriskthataninfantwillbebornwithaneura...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2007年85卷第1期DifferentialRegulationandRelocalizationofthePlateletP2YReceptorsafterActivation:AWaytoAvoidLossofHemostaticProperties
...epresentstudy,weinvestigatedthedesensitizationandtraffickingoftheP2Y1andP2Y12receptorsafteragonist-inducedstimulationofplateletsorastrocytomacellstransfectedwiththeP2Y1orP2Y12receptorsfusedtogreenfluorescentprotein.Inplateletsandintransfectedcells,exposureto10eADPcauseddesensitizationoftheP2Y1recept...
醫源資料庫;在線期刊;分子藥理學雜誌;2005年第67卷第3期MethylmalonicacidandcognitivefunctionintheMedicalResearchCouncilCognitiveFunctionandAgeingStudy
...142EN.E-mail:andrew{at}mccaddon.demon.co.uk.Seecorrespondingeditorialonpage1259.ABSTRACTBackground:Anelevatedbloodconcentrationofhomocysteineisanestablishedriskfactorforcognitiveimpairmentanddementia,butassociationsbetweencognitionandmethylmalonicacid(MMA),arelatedmetabolicmarkerofvitaminB-12deficie...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2006年84卷第6期