肺大細胞神經內分泌癌1例報告
...(NSE)、CEA、角蛋白均表達陽性,嗜鉻粒蛋白(CHG-A)、Leu-7、突觸素、蛙皮素部分表達陽性,電鏡下見神經內分泌顆粒特徵[3]。LCNEC還須和分化差的腺癌、鱗癌、肉瘤、淋巴瘤和惡性黑色素瘤相鑑別。LCNEC是一種侵襲性強的惡...
合作平臺;在線期刊;中華現代臨牀醫學雜誌;2004年第2卷第7B期乳製品中L-羥脯氨酸的檢測
...纈氨酸;12.Met蛋氨酸;13.Cys半胱氨酸;14.Ile異亮氨酸;15.Leu亮氨酸;16.Trp色酸;17.Phe苯丙氨酸;18.His組氨酸;19.DNFB2,4-二硝基苯;20.Lys賴氨酸;21.Tyr酪氨酸圖220μg/mLL-羥脯氨酸標準品色譜圖圖3奶粉樣品色譜圖圖4奶粉中添加20μg/mLL...
藥品天地;專業藥學;實驗技術;色譜技術;色譜分析實例TheThree-SubstitutedIndolinoneCyclin-DependentKinase2Inhibitor3-[1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one(SU9516)Kill
...h-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one(SU9516)wereexaminedinhumanleukemiacells.ExposureofU937andotherleukemiacellstoSU9516concentrations5µMrapidly(i.e.,within4h)inducedcytochromecrelease,Baxmitochondrialtranslocation,andapoptosisinassociationwithpronounceddown-regulationoftheantiapop...
醫源資料庫;在線期刊;分子藥理學雜誌;2006年第68卷第8期TheTwoIsoformsoftheNa+/Ca2+Exchanger,NCX1andNCX3,ConstituteNovelAdditionalTargetsfortheProsurvivalActionofAkt/ProteinKinaseBPathway
...3transcriptdidnotincreaseand2)theproteasomeinhibitorN-benzyloxycarbonyl(Z)-Leu-Leu-leucinal(MG-132)didnotfurtherenhanceNCX3proteinlevelsinAkt1activemutantsasitwouldbeexpectediftheubiquitin-proteasomecomplexwasnotalreadyblockedbyAkt1pathway.Asexpected,inPC-12Tet-Offwild-typecellsMG-132enhancedNCX3pro...
醫源資料庫;在線期刊;分子藥理學雜誌;2008年第70卷第3期VariationinITGB3IsAssociatedwithAsthmaandSensitizationtoMoldAllergeninFourPopulations
...cantassociationbetweenanaminoacidpolymorphismintheP-selectingene(SELPVal640Leu)andatopyintheHutterites(5).P-selectinisanintegrinstoredinplateletandendothelialcellgranules.P-selectinisreleasedbyactivatedcellstomediateinteractionwithleukocytesandmaythusinfluencetheinflammatoryresponseinasthma.Severalg...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2005年第171卷第7期PharmacologicalCharacterizationofaNovelNonpeptideAntagonistforFormylPeptideReceptor-Like1
...]Trp-Lys-Tyr-Met-Val-D-Met-NH2(WKYMVm)bindingtoFPRL1butnot[3H]N-formyl-Met-Leu-Phetoformylpeptidereceptor.InfunctionalassaysusingFPRL1-expressingRBL-2H3cells,C7inhibitedcalciummobilizationandchemotaxisinducedbyWKYMVmandC1anddegranulationelicitedbyC1.C7alsosuppressedC1-inducedextracellularsignal-regu...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第10期接種卡介苗導致死亡1例
...血WBC20.6×109/L,NEUT82.3%,LYMPH14.1%,RBC3.06×1012/L,HGB69g/L;尿LEU++,PRO+,ERY++,SRC+,肝功ALT43.2IU/L,ALB31.8g/L,AST98U/L,ALP188.2U/L,GGT83.6IU/L;血離子:K+4.33mmol/L,Na+120.96mmol/L,Cl-103.25mmol/L,TcA2.84mmol/L;腰穿腦脊液無色透明,潘氏反應弱陽...
醫源資料庫;在線期刊;中華醫學研究雜誌;2005年第5卷第7期Doxycycline—aroleinocularsurfacerepair
...attheocularsurfaceandprobablyrelatestoitschelatingproperties.Keywords:interleukin-1;cornealepithelialcells;cornealkeratocytes;doxycycline;matrixmetalloproteinasesAbbreviations:FCS,fetalcalfserum;HRP,horseradishperoxidase;LPS,lipopolysaccharide;MMP,matrixmetalloproteinase;PBS,phosphatebufferedsaline;...
醫源資料庫;在線期刊;英國眼科學雜誌;2004年第88卷第5期5-AndrostenediolPromotesSurvivalof-IrradiatedHumanHematopoieticProgenitorsthroughInductionofNuclearFactor-BActivationandGranulocyteColony-Stim
...ndinducedNFBgeneexpressionandNFBactivation(DNAbinding).5-AEDstimulatedinterleukin-6andgranulocytecolony-stimulatingfactor(G-CSF)secretion.Thesurvival-enhancingeffectsof5-AEDonclonogeniccellswereabrogatedbysmallinterferingRNAinhibitionofNFBgeneexpressionandbyneutralizationofG-CSFwithantibody.Theeffec...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第8期Caspase-dependentand-independentpathwaysforcadmium-inducedapoptosisinculturedkidneyproximaltubulecells
...essinapoptoticcellsisthecondensationandfragmentationofchromatinwithinthenucleus,whereastheplasmamembraneremainsintact,preventingleakageofthecytosoliccontentsintotheextracellularspace.Incontrast,necroticcellsswellandburst,spillingtheircontentsintotheextracellularspacecausinganinflammatoryresponse.Inp...
醫源資料庫;在線期刊;美國生理學雜誌;2006年第289卷第10期