PossibleinvolvementofpregnaneXreceptor–enhancedCYP24expressionindrug-inducedosteomalacia
...unknown.Hereweshowthatthesedrugsleadtotheupregulationof25-hydroxyvitaminD3-24-hydroxylase(CYP24)geneexpressionthroughtheactivationofthenuclearreceptorpregnaneXreceptor(PXR;NR1I2).CYP24isamitochondrialenzymeresponsibleforinactivatingvitaminDmetabolites.CYP24mRNAisupregulatedinvivoinmicebypregnenolone...
醫源資料庫;在線期刊;臨牀研究雜誌;2005年第115卷第1期HIV-1p24抗原檢測的應用研究
HIV-1p24抗原檢測的應用研究中國免疫學雜誌2000年第3期第16卷免疫學技術與方法作者:尹紅章 李秀華 孟淑芳 宋愛京 李德富單位:尹紅章(中國藥品生物製品檢定所衛生部生物技術產品檢定及標準化研究重點實驗室,北京100...
合作平臺;醫學論文;臨牀醫學與專科論文;檢驗醫學關於部分醫療器械產品生產企業更名和增加產品規格後予以更換生產許可證的通知
...───┤│1│玉環縣華康醫療器械有│一次性輸液器│xk24-ll60096│更名爲:浙江台州注射器廠│││限公司││││├──┼──────────┼──────┼──────────┼───────────────...
醫源資料庫;醫藥衛生法規大全;藥政類(藥品、食品、器械);醫療器械法規關於部分醫療器械產品生產企業更名和增加產品規格後予以更換生產許可證的通知”的通知
...│1│玉環縣民生醫療器械廠│一次性使用無菌注射器│XK24-1380049│更名爲:浙江玉升醫療││││││器械有限公司│├──┼──────────┼──────────┼───────┼──────────┤│2│玉...
醫源資料庫;醫藥衛生法規大全;藥政類(藥品、食品、器械);醫療器械法規EvaluationofanUltrasensitivep24AntigenAssayasaPotentialAlternativetoHumanImmunodeficiencyVirusType1RNAViralLoadAssayinResource-LimitedS
...ntassaymethodforhumanimmunodeficiencyvirustype1quantitation,ultrasensitivep24antigenassay(Up24),wascomparedwithRNAviralloadassay(VL).Up24had100%sensitivityofdetectionataviralloadof30,000,withsensitivityof46.4%ataviralloadof30,000(232specimensfrom65seropositivesubjects).Theassaywashighlyreproducible,...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第1期Anthropometry-basedreferencevaluesfor24-hurinarycreatinineexcretionduringgrowthandtheiruseinendocrineandnutritionalresearch
...children.Objective:Wesoughttoestablishanthropometry-basedreferencevaluesfor24-hurinarycreatinineexcretioninhealthywhitechildrenaged318y.Design:Anthropometricvariablesand24-hurinarycreatinineexcretionratesweredeterminedcross-sectionally(225boysand229girls).Ageandsexdependencyof24-hcreatinineexc...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2002年75卷第3期Effectoffat-reduceddietson24-henergyexpenditure:comparisonsbetweenanimalprotein,vegetableprotein,andcarbohydrate
...evantforthepreventionandtreatmentofobesityiftheseeffectscanbemaintainedover24h.Objective:Theeffectsofpork-meatprotein,soyprotein,andcarbohydrateon24-henergyexpenditurewerecompared.Design:Twelveyoung,healthy,overweightandmildlyobese[bodymassindex(inkg/m2):2632]nonsmokingmenparticipatedinarandom...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2000年72卷第5期PrelaminAandlaminAappeartobedispensableinthenuclearlamina
...syl–prelaminA(asoccurswithadeficiencyintheprelaminAprocessingenzymeZmpste24)causeddramaticallymisshapennucleiandprogeria-likediseasephenotypes.TheapparentdispensabilityofprelaminAsuggestedthatlaminA–relatedprogeroidsyndromesmightbetreatedwithimpunitybyreducingprelaminAsynthesis.Remarkably,thepre...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第3期RapidGrowthofInvasiveMetastaticMelanomainCarcinogen-TreatedHepatocyteGrowthFactor/ScatterFactor-TransgenicMiceCarryinganOncogenicCDKMutation
...nducedmelanomasintheskinofmicecarryingamutatedcyclin-dependentkinase4(CDK4R24C).Deregulatedreceptortyrosinekinasesignaling,whichisanotherimportantfeatureofhumanmelanoma,leadstospontaneousdevelopmentofmetastaticmelanomaafteralonglatencyperiodinmiceoverexpressinghepatocytegrowthfactor/scatterfactor(HG...
醫源資料庫;在線期刊;美國病理學雜誌;2006年第168卷第8期ComparisonofTwoHumanImmunodeficiencyVirus(HIV)RNASurrogateAssaystotheStandardHIVRNAAssay
...preaduseoftheassayinresource-limitedsettings.ThePerkin-ElmerUltrasensitivep24assayandtheCavidiExavirLoadassaybothofferpotentiallysimpler,lesscostlytechnologiesformonitoringviralload.TheseassayswerecomparedtotheRocheAmplicorHIV-1MonitorTest,v1.5,usingpanelsofclinicalsamples(subtypeB)fromHIV-positives...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第12期