RelationshipsamongCD14andCC16Genotypes,PlasmaLevels,andSeverity
...tswithstablediseaseandhavenotdefinedmechanismsimportantduringacuteasthma.CD14andCC16eachplayakeyroleinbiologicallyimportantinflammatorypathwaysandthegeneofeachhasafunctionalpromoter-regionpolymorphism.Objectives:Thisstudywasdesignedtodeterminetheinfluenceofthesepolymorphismsonplasmalevelsoftheirprod...
醫源資料庫;在線期刊;美國呼吸和危急護理醫學;2006年第173卷第6期IdentificationandCharacterizationofaNewTubulin-BindingTetrasubstitutedBrominatedPyrrole
...ibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylicacidethylester(JG-03-14)andfoundthatitisapotentmicrotubuledepolymerizer.JG-03-14causedadose-dependentlossofcellularmicrotubules,formationofaberrantmitoticspindles,accumulationofcellsintheG2/Mphaseofthecellcycle,andBcl-2phosphorylation.Theseevents...
醫源資料庫;在線期刊;分子藥理學雜誌;2007年第69卷第7期InhibitionofTNFreceptor1internalizationbyadenovirus14.7Kasanovelimmuneescapemechanism
...Cologne,UniversityofCologne,Cologne,Germany.AbstractTheadenoviralproteinE3-14.7K(14.7K)isaninhibitorofTNF-inducedapoptosis,butthemolecularmechanismunderlyingthisprotectiveeffecthasnotyetbeenexplainedexhaustively.TNF-mediatedapoptosisisinitiatedbyligand-inducedrecruitmentofTNFreceptor–associateddea...
醫源資料庫;在線期刊;臨牀研究雜誌;2006年第116卷第11期DifferentialHealingActivitiesofCD34+andCD14+EndothelialCellProgenitors
...atetheirinvivoeffects.MethodsandResults-HumanCD34+primitiveprogenitorsandCD14+monocyticprogenitorswereinjectedlocallyintotheischemiclimbsofdiabeticmice.CD14+celltherapyimprovedhealingandvesselgrowth,althoughnotasrapidlyoreffectivelyasCD34+celltreatment.Westernblotanalysisrevealedthatcelltherapymodul...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第4期TowardtheDevelopmentofanAntidisease,Transmission-BlockingIntranasalVaccineforGroupAStreptococcus
...ventGASinfection,aconformationallyconstrainedandminimallyconservedpeptide,J14,fromtheMproteinofGAShasbeendefined.Inthepresentstudy,J14wasformulatedwithbacterialoutermembraneproteins(proteosomes)andthenintranasallyadministeredtooutbredmicewithoutadditionaladjuvant.SuchimmunizationledtohightitersofJ14...
醫源資料庫;在線期刊;傳染病學雜誌;2005年第191卷第20期碳-14-呼氣試驗對胃幽門螺旋桿菌的療效分析
【摘要】目的探討碳-14-呼氣試驗(簡稱14C-UBT)指導藥物治療Hp具有臨牀應用價值。方法經胃鏡和首次14C-UBT檢查均爲陽性的胃潰瘍(26例)、淺表性胃炎(69例)、萎縮性胃炎(33例)患者共計128例,將這些患者分爲3組:A組爲患...
醫源資料庫;在線期刊;中華醫學實踐雜誌;2006年第5卷第5期ProtectionofEndothelialSurvivalbyPeroxisomeProliferator-ActivatedReceptor-Mediated14-3-3Upregulation
...ticactionofcPGI2andL-165041.OurresultsshowforthefirsttimethatPGI2stimulated14-3-3expressionviaPPARactivation.cPGI2andL-165041inducedbindingoafPPARtoPPARresponseelementslocatedbetween-1426and-1477of14-3-3promoterregion,therebyactivating14-3-3promoteractivityandproteinexpression.Upregulationof14-3-3pr...
醫源資料庫;在線期刊;動脈硬化血栓血管生物學雜誌;2006年第26卷第7期可溶性CD14和HCMV感染與冠心病病情變化關係
【摘要】 目的探討可溶性CD14(sCD14)和人鉅細胞病毒(HCMV)感染與冠心病(CHD)病情變化的關係。方法應用ELISA法測定120例CHD病人血清sCD14和HCMVIgG的濃度,其中急性心肌梗死(AMI)、不穩定型心絞痛(UAP)和穩定型心絞痛...
醫源資料庫;在線期刊;齊魯醫學雜誌;2010年第25卷第1期Afeasibilitystudyquantifyinginvivohuman-tocopherolmetabolism
...epartmentofAgriculture,ARS,BHNRC,Beltsville,MD(JAN)2Supportedbygrantno.DKRO148307,NationalCenterforResearchResourcesgrantno.RR13461fromtheNationalInstitutesofHealth,Contractno.W-7405-Eng-48fromtheUSDepartmentofEnergy(toLawrenceLivermoreNationalLaboratory),andHoffmannLaRoche.Hoffmann-LaRochedonatedth...
醫源資料庫;在線期刊;美國臨牀營養學雜誌;2006年84卷第6期OppositelydirectedH+gradientfunctionsasadrivingforceofratH+/organiccationantiporterMATE
...edtoexistinHEK-rMATE1cells,andthetransportofvariousorganiccationsincluding[14C]tetraethylammoniumwasstimulatedinintracellularacidifiedHEK-rMATE1cellsbutnotmockcells.Thetransportof[14C]tetraethylammoniuminmembranevesiclesfromHEK-rMATE1cellsexhibitedtheovershootphenomenononlywhentherewasanoutwardlydir...
醫源資料庫;在線期刊;美國生理學雜誌;2007年第290卷第2期