心理所揭示神經軟體徵在區分精神分裂症譜系上具有敏感性和特異性
...letin雜誌。Chan,R.C.K.*,Xie,W.Z.,Geng,F.L.,Wang,Y.,Lui,S.S.Y.,Wang,C.Y.,Yu,X.,Cheung,E.F.C.,Rosenthal,R.Clinicalutilityandlifespanprofilingofneurologicalsoftsignsinschizophreniaspectrumdisorders.SchizophreniaBulletin,2015,doi:10.1093/schbul/sbv196.作者:
醫藥經濟;生物技術;技術要聞ProspectiveEstimationofRecombinationSignalEfficiencyandIdentificationofFunctionalCrypticSignalsintheGenomebyStatisticalModeling
...endedthePCRprogram.PCRproductswereelectrophoresedover1%agarosegelstoidentifyunmodified(900-bpproduct)andrearranged(600-bpproduct)plasmids.FinalvaluesforR(nos.rearrangedplasmids÷[nos.rearrangedplasmids+nos.unmodifiedplasmids])wereaveragedfromfiveindependentelectroporations.All600-bpproductsfromrearr...
醫源資料庫;在線期刊;實驗醫學雜誌;2003年第197卷第2期ProspectiveEstimationofRecombinationSignalEfficiencyandIdentificationofFunctionalCrypticSignalsintheGenomebyStatisticalModeling
...endedthePCRprogram.PCRproductswereelectrophoresedover1%agarosegelstoidentifyunmodified(900-bpproduct)andrearranged(600-bpproduct)plasmids.FinalvaluesforR(nos.rearrangedplasmids÷[nos.rearrangedplasmids+nos.unmodifiedplasmids])wereaveragedfromfiveindependentelectroporations.All600-bpproductsfromrearr...
醫源資料庫;在線期刊;美國病理學雜誌;2003年第162卷第2期InternationalandMulticenterComparisonofEUCASTandCLSIM27-A2BrothMicrodilutionMethodsforTestingSusceptibilitiesofCandidaspp.toFluconazole,It
...tisolateswereobtainedfromeachcenter(92to100%)atthisincubationtime.NguyenandYu(7)havereportedsimilarresults.Amongthespecies,thelongerincubationtimemayberequiredforisolatesofC.dubliniensis,because35%oftheno-growthreportswereforthisspecies;otherthanthat,MICswerereadilydeterminedat24hbybothmethods.Ashor...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第8期DepartmentofMicrobiologyandImmunology,UniversityofMichiganMedicalSchool,AnnArbor,MI48109
...edbyactivation-inducedcytidinedeaminase(AID)upondeaminationofcytidinetodeoxyuracil.Patch-excisionrepairoftheselesionsinvolvingerrorproneDNApolymerasessuchaspolcausesmutationsatallbasepositions.Ifnotrepaired,thedeaminatednucleotidesonthecodingandnoncodingstrandsresultinC-to-TandG-to-Aexchanges,respec...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第201卷第9期一年11個三期研究!羅氏自信強力打造PD-L1藥物
一直以來,在生物醫藥產業中都有兵貴神速的說法。許多生物製藥巨頭都希望能夠儘快縮短藥物的研發和審批週期以儘快將藥物推上市場。爲了達到這一目標,有時一些生物醫藥巨頭還會以限制一種新藥的臨牀三期項目數量以達...
藥品天地;專業藥學;藥學研究DetectionofHumanImmunodeficiencyVirusType1DNAinDriedBloodSpotsbyaDuplexReal-TimePCRAssay
...positivemothersinremoteareasoftheworld.INTRODUCTIONFilterpaperswereinitiallyusedforbloodcollection,transportation,storage,andscreeningfornewbornmetabolicdisorders(9,10).WiththeavailabilityofPCR-basednucleicacidamplificationtechnology,theirusehasbeenextendedtothedetectionandidentificationofavarietyof...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第4期Treatmentofadvancedtumorswithagonisticanti-GITRmAbanditseffectsontumor-infiltratingFoxp3+CD25+CD4+regulatoryTcells
...echanismsandmanipulationintumorimmunotherapy.Annu.Rev.Immunol.19:565–594.Yu,P.,Y.Lee,W.Liu,T.Krausz,A.Chong,H.Schreiber,andY.X.Fu.2005.IntratumordepletionofCD4+cellsunmaskstumorimmunogenicityleadingtotherejectionoflate-stagetumors.J.Exp.Med.201:779–791.Phan,G.Q.,J.C.Yang,R.M.Sherry,P.Hwu,S.L.Top...
醫源資料庫;在線期刊;實驗醫學雜誌;2005年第202卷第7期MultilocusSequenceTypingSchemeThatProvidesBothSpeciesandStrainDifferentiationfortheBurkholderiacepaciaComplex
...ulnerablemembersofthecommunity(30).VariousmoleculartypingmethodsarecurrentlyutilizedforthediscriminationoftheBCC.TechniquesusingthesinglelocusoftherecAgene,suchasrestrictionfragmentlengthpolymorphisms(RFLP),aretransferablebutofferlimitedresolutionandareprimarilyappliedasameansofidentificationattheBC...
醫源資料庫;在線期刊;微生物臨牀雜誌;2005年第43卷第9期LossofSOCS3inThelpercellsresultedinreducedimmuneresponsesandhyperproductionofinterleukin10andtransforminggrowthfactor–1
...choolofMedicalSciences,3DepartmentofParasitology,FacultyofMedicalSciences,KyushuUniversity,Higashi-ku,Fukuoka812-8582,JapanSuppressorofcytokinesignaling(SOCS)3isamajornegativefeedbackregulatorofsignaltransducerandactivatoroftranscription(STAT)3-activatingcytokines.Transgenicmousestudiesindicatethath...
醫源資料庫;在線期刊;實驗醫學雜誌;2006年第203卷第4期